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Cell Death
Cell Death
PARP1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
Skeletal muscle biology / Oxidative Stress / Mitochondria / DNA damage / Energy Metabolism / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology
Src Kinase Inhibition Improves Acute Outcomes After Experimental Intracerebral Hemorrhage
Behavior / Treatment Outcome / Enzyme Inhibitors / Apoptosis / Stroke / Glucose Metabolism / Animals / Male / Cell Death / Kinase inhibitor / Clinical Sciences / Apoptose / Src kinase / Rats / Blood Flow / Intracerebral Hemorrhage / Pyrazoles / Cerebral Hemorrhage / Neurosciences / Direct Injection / Matrix Metalloproteinase / Glucose Metabolism / Animals / Male / Cell Death / Kinase inhibitor / Clinical Sciences / Apoptose / Src kinase / Rats / Blood Flow / Intracerebral Hemorrhage / Pyrazoles / Cerebral Hemorrhage / Neurosciences / Direct Injection / Matrix Metalloproteinase
Antimicrobial activities of commercial nanoparticles against an environmental soil microbe, Pseudomonas putida KT2440
Biological Engineering / Antimicrobial activity / Heavy Metal / Cell Death / Plant growth / Pseudomonas putida / Particle Size / Microbial Activity / Pathogenic Bacteria / Pseudomonas putida / Particle Size / Microbial Activity / Pathogenic Bacteria
Arsenic Trioxide Inhibits Neuroblastoma Growth in Vivo and Promotes Apoptotic Cell Death in Vitro
Apoptosis / Cell Division / Caspases / Cell line / Cell Differentiation / Humans / Cell Death / Biochemical / Differentiation / Arsenic trioxide / Caspase / Neuroblastoma / Retinoic Acid / Clinical Study / Tretinoin / Oxides / Thiazoles / Cell Survival / Tumor Growth / Antineoplastic Agents / Arsenicals / Acute Promyelocytic Leukemia / Nude mice / Biochemistry and cell biology / Humans / Cell Death / Biochemical / Differentiation / Arsenic trioxide / Caspase / Neuroblastoma / Retinoic Acid / Clinical Study / Tretinoin / Oxides / Thiazoles / Cell Survival / Tumor Growth / Antineoplastic Agents / Arsenicals / Acute Promyelocytic Leukemia / Nude mice / Biochemistry and cell biology
Arsenic trioxide and neuroblastoma cytotoxicity
Clinical Trial / Bioenergetics / Cell Differentiation / Humans / Cancer Therapy / Multidrug Resistance / Drug Resistance / Cell Death / Arsenic trioxide / Neuroblastoma / Oxides / Antineoplastic Agents / Arsenicals / Brain Neoplasms / Biochemistry and cell biology / Multidrug Resistance / Drug Resistance / Cell Death / Arsenic trioxide / Neuroblastoma / Oxides / Antineoplastic Agents / Arsenicals / Brain Neoplasms / Biochemistry and cell biology
Misincorporation of free m-tyrosine into cellular proteins: a potential cytotoxic mechanism for oxidized amino acids
Protein synthesis / Biological Sciences / Animals / Cell Death / Biochemical / Proteins / CHEMICAL SCIENCES / Phenylalanine / Oxidative Damage / Spectrum analysis / Amino Acid Profile / In Vitro Studies / Oxidation-Reduction / Protein Biosynthesis / Tyrosine / COL / Cycloheximide / Proteins / CHEMICAL SCIENCES / Phenylalanine / Oxidative Damage / Spectrum analysis / Amino Acid Profile / In Vitro Studies / Oxidation-Reduction / Protein Biosynthesis / Tyrosine / COL / Cycloheximide
UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells
Leukemia / Apoptosis / Molecular Mechanics / Cell line / Humans / Congestive Heart Failure / Cell Death / Biochemical / BIOCHEMICAL PHARMACOLOGY / Molecular Structure / Congestive Heart Failure / Cell Death / Biochemical / BIOCHEMICAL PHARMACOLOGY / Molecular Structure
A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo
Psychology / Neuropharmacology / Mitochondria / Neuroprotection / Brain / Glucose / Animals / Plant tissue Culture Techniques / Male / Cell Death / Benzodiazepines / Brain Ischemia / Wistar Rats / Neurosciences / Excitatory Amino Acids / Neuroprotective Agents / Glucose / Animals / Plant tissue Culture Techniques / Male / Cell Death / Benzodiazepines / Brain Ischemia / Wistar Rats / Neurosciences / Excitatory Amino Acids / Neuroprotective Agents
Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides
RNA interference / Humans / Cell Death / Peptides / Clinical Sciences / microRNAs / Cell nucleus / HeLa cells / Molecular weight / Oxidation-Reduction / microRNAs / Cell nucleus / HeLa cells / Molecular weight / Oxidation-Reduction
Human postnatal dental pulp cells co-differentiate into osteoblasts and endotheliocytes: a pivotal synergy leading to adult bone tissue formation
Immunology / Stem Cells / Cancer / Flow Cytometry / Transmission Electron Microscopy / Stem Cell / Apoptosis / Stem Cell Transplantation / Biological Sciences / Cell Differentiation / Humans / Animals / Cell Death / Cdd / Neurons / Differentiation / Chip / Rats / Adult / Endothelial cell / Time Factors / Adipocytes / Stromal Cells / Three Dimensional / Wistar Rats / Osteogenesis / Angiotensin Converting Enzyme / Osteoblasts / Gene expression profiling / Cell Growth / Stem Cell / Apoptosis / Stem Cell Transplantation / Biological Sciences / Cell Differentiation / Humans / Animals / Cell Death / Cdd / Neurons / Differentiation / Chip / Rats / Adult / Endothelial cell / Time Factors / Adipocytes / Stromal Cells / Three Dimensional / Wistar Rats / Osteogenesis / Angiotensin Converting Enzyme / Osteoblasts / Gene expression profiling / Cell Growth
Protective effect of melatonin in a chronic experimental model of Parkinson’s disease
Cognitive Science / Electron Microscopy / Immunohistochemistry / Oxidative Stress / Free Radical / Organelles / Melatonin / Brain / Low Dose / Mice / Chronic Disease / Blood brain barrier / Animals / Male / Cell Death / Substantia nigra / Neurons / Tyrosine Hydroxylase / Degeneration / Side Effect / Axons / Neurosciences / Neuroprotective Agents / Experimental Model / DNA fragmentation / Organelles / Melatonin / Brain / Low Dose / Mice / Chronic Disease / Blood brain barrier / Animals / Male / Cell Death / Substantia nigra / Neurons / Tyrosine Hydroxylase / Degeneration / Side Effect / Axons / Neurosciences / Neuroprotective Agents / Experimental Model / DNA fragmentation
Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis
Oxidative Stress / Amyotrophic Lateral Sclerosis / Humans / Mice / Female / Animals / Male / Cell Death / Substantia nigra / Superoxide Dismutase / Phenotype / Clinical Sciences / Transgenic Mouse Technology / Neurosciences / Animals / Male / Cell Death / Substantia nigra / Superoxide Dismutase / Phenotype / Clinical Sciences / Transgenic Mouse Technology / Neurosciences
Cellular prion protein regulates intracellular hydrogen peroxide level and prevents copper-induced apoptosis
Flow Cytometry / Apoptosis / Cerebellum / Copper / Mice / Animals / Cell Death / Neurons / Hydrogen Peroxide / Cell nucleus / Prions / Time Factors / Protein Binding / Cell Survival / Biochemistry and cell biology / Prion Protein / Animals / Cell Death / Neurons / Hydrogen Peroxide / Cell nucleus / Prions / Time Factors / Protein Binding / Cell Survival / Biochemistry and cell biology / Prion Protein
Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death
Cardiovascular / Toll like receptor signaling / Humans / Endothelial Cells / Reactive Oxygen Species / Cell Death / Lipopolysaccharides / Sodium / Cell Size / Cell Death / Lipopolysaccharides / Sodium / Cell Size
A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma
Computational Biology / Membrane Proteins / Signal Transduction / RNA interference / Humans / Medulloblastoma / Cell Death / microRNAs / Neoplasm Invasiveness / Prognosis / Transfection / Cell Proliferation / Antineoplastic Agents / Molecular Targeted Therapy / RNAi Therapeutics / Gene expression profiling / Medulloblastoma / Cell Death / microRNAs / Neoplasm Invasiveness / Prognosis / Transfection / Cell Proliferation / Antineoplastic Agents / Molecular Targeted Therapy / RNAi Therapeutics / Gene expression profiling
In vitro and in vivo leishmanicidal activity of Astronium fraxinifolium (Schott) and Plectranthus amboinicus (Lour.) Spreng against Leishmania (Viannia) braziliensis
Complementary and Alternative Medicine / Plant Biology / Medicinal Plants / Phytomedicine / Biological Sciences / Phytotherapy / Leishmaniasis / Cell line / Humans / Mice / Female / Animals / Male / Cell Death / Visceral Leishmaniasis / Naphthoquinones / Meliaceae / Anacardiaceae / Biomed / CHEMICAL SCIENCES / Plant extracts / Cutaneous Leishmaniasis / Phytotherapy / Leishmaniasis / Cell line / Humans / Mice / Female / Animals / Male / Cell Death / Visceral Leishmaniasis / Naphthoquinones / Meliaceae / Anacardiaceae / Biomed / CHEMICAL SCIENCES / Plant extracts / Cutaneous Leishmaniasis
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