Biological activity

Aza-bicyclic amino acid sulfonamides as α4β1/α4β7 integrin antagonists

Organic Chemistry / Amino Acid Profile / Conformational Analysis / Biological activity

Obtención de derivados 1-NSustituidosde Melatonina

Sleep / Biological activity / Receiver

[Synthetic analogues of antimicrobial peptides from the venom of the Central Asian spider Lachesana tarabaevi]

Spiders / Escherichia coli / Animals / Antimicrobial Peptide / Anti-Bacterial Agents / Antimicrobial Cationic Peptides / Bacillus subtilis / Amino Acid Profile / Mechanism of action / Biological activity / Amino Acid Sequence / Structure activity Relationship / Erythrocytes / Hemolysis / Bilayer Lipid Membrane / Disulfide bond / Molecular Sequence Data / Antimicrobial Cationic Peptides / Bacillus subtilis / Amino Acid Profile / Mechanism of action / Biological activity / Amino Acid Sequence / Structure activity Relationship / Erythrocytes / Hemolysis / Bilayer Lipid Membrane / Disulfide bond / Molecular Sequence Data

HIV-1 integrase inhibitory substances fromColeus parvifolius

Traditional Medicine / Thailand / Pharmacognosy / HIV / Biological Sciences / Phytotherapy / In Vitro / Humans / Virus / Flowers / Fruit / Plant Roots / CHEMICAL SCIENCES / Plant extracts / Seeds / Microbial Sensitivity Tests / Integrase / Biological activity / Mixture / HIV Integrase / Plant Leaves / Phytotherapy / In Vitro / Humans / Virus / Flowers / Fruit / Plant Roots / CHEMICAL SCIENCES / Plant extracts / Seeds / Microbial Sensitivity Tests / Integrase / Biological activity / Mixture / HIV Integrase / Plant Leaves

Essential oil components and biological activities of Coleus parvifolius leaves

Mass Spectrometry / Essential Oil / Escherichia coli / Gram Positive / Antimicrobial activity / Staphylococcus aureus / Candida albicans / Gas Chromatography / Gram Positive Bacteria / Antioxidant Activity / Gram-negative bacteria / MDR Salmonella typhi / Bacillus subtilis / Biological activity / Staphylococcus aureus / Candida albicans / Gas Chromatography / Gram Positive Bacteria / Antioxidant Activity / Gram-negative bacteria / MDR Salmonella typhi / Bacillus subtilis / Biological activity

HIV-1 integrase inhibitory substances fromColeus parvifolius

Traditional Medicine / Thailand / Pharmacognosy / HIV / Biological Sciences / Phytotherapy / In Vitro / Humans / Virus / Flowers / Fruit / Plant Roots / CHEMICAL SCIENCES / Plant extracts / Seeds / Microbial Sensitivity Tests / Integrase / Biological activity / Mixture / HIV Integrase / Plant Leaves / Phytotherapy / In Vitro / Humans / Virus / Flowers / Fruit / Plant Roots / CHEMICAL SCIENCES / Plant extracts / Seeds / Microbial Sensitivity Tests / Integrase / Biological activity / Mixture / HIV Integrase / Plant Leaves

Gamma Interferon Loaded onto Albumin Nanoparticles: In Vitro and In Vivo Activities against Brucella abortus

Microbiology / Medical Microbiology / Nanoparticle / Macrophages / Pharmaceutical Chemistry / In Vitro / Humans / Albumin / Mice / Nitric oxide / Animals / Bacteria / Nanostructures / Brucellosis / In Vivo / Delivery System / Charge / Antimicrobial agents / Biological activity / Drug Carriers / Brucella abortus / Interferon gamma / In Vitro / Humans / Albumin / Mice / Nitric oxide / Animals / Bacteria / Nanostructures / Brucellosis / In Vivo / Delivery System / Charge / Antimicrobial agents / Biological activity / Drug Carriers / Brucella abortus / Interferon gamma

Studies on quinones. Part 47. Synthesis of novel phenylaminophenanthridinequinones as potential antitumor agents

Organic Chemistry / Cytotoxicity / Cell line / In Vitro / Humans / Quinones / Nitrogen / European / Biological activity / Antitumor Activity / Human Fibroblasts / Structure activity Relationship / Chemical Synthesis / Cell Survival / Antineoplastic Agents / Regioselectivity / Molecular Structure / aniline Compounds / Quinones / Nitrogen / European / Biological activity / Antitumor Activity / Human Fibroblasts / Structure activity Relationship / Chemical Synthesis / Cell Survival / Antineoplastic Agents / Regioselectivity / Molecular Structure / aniline Compounds

An in vitro comparative study with furyl-1,4-quinones endowed with anticancer activities

Comparative Study / Protein synthesis / Software / Liver / Cancer Therapy / Mice / Animals / Male / Hepatocellular Carcinoma / Cell Death / Glutathione / Quinones / Cell Transplantation / Caspase / Rats / Wistar Rats / Biological activity / Physico chemical Properties / Cell Survival / Antineoplastic Agents / Protein Biosynthesis / Anticancer Drug / Adenosine Triphosphate / Safety Factor / Liver Tumor / Mice / Animals / Male / Hepatocellular Carcinoma / Cell Death / Glutathione / Quinones / Cell Transplantation / Caspase / Rats / Wistar Rats / Biological activity / Physico chemical Properties / Cell Survival / Antineoplastic Agents / Protein Biosynthesis / Anticancer Drug / Adenosine Triphosphate / Safety Factor / Liver Tumor

Studies on quinones. Part 47. Synthesis of novel phenylaminophenanthridinequinones as potential antitumor agents

Organic Chemistry / Cytotoxicity / Cell line / In Vitro / Humans / Quinones / Nitrogen / European / Biological activity / Antitumor Activity / Human Fibroblasts / Structure activity Relationship / Chemical Synthesis / Cell Survival / Antineoplastic Agents / Regioselectivity / Molecular Structure / aniline Compounds / Quinones / Nitrogen / European / Biological activity / Antitumor Activity / Human Fibroblasts / Structure activity Relationship / Chemical Synthesis / Cell Survival / Antineoplastic Agents / Regioselectivity / Molecular Structure / aniline Compounds

An antimicrobial peptide Ar-AMP from amaranth (Amaranthus retroflexus L.) seeds

Phytochemistry / Fungi / Biological Sciences / Peptides / Antimicrobial Peptide / CHEMICAL SCIENCES / Molecular cloning / Protein Sequence Analysis / Amaranthus / Seeds / Botrytis cinerea / Microbial Sensitivity Tests / Amino Acid Profile / Cysteine / Biological activity / Amino Acid Sequence / Chitin / Rhizoctonia solani / Molecular Sequence Data / CHEMICAL SCIENCES / Molecular cloning / Protein Sequence Analysis / Amaranthus / Seeds / Botrytis cinerea / Microbial Sensitivity Tests / Amino Acid Profile / Cysteine / Biological activity / Amino Acid Sequence / Chitin / Rhizoctonia solani / Molecular Sequence Data

Statistical Model To Evaluate In Vivo Activities of Antimalarial Drugs in a Plasmodium cynomolgi-Macaque Model for Plasmodium vivax Malaria

Microbiology / Medical Microbiology / Drug development / Prodrugs / Mixed Effects Models / Female / Animals / Drug Resistance / Male / Animal Model / South America / Animal Experimentation / In Vivo / Antimalarials / Rhesus macaques / Antimicrobial agents / Macaca Mulatta / Sub Saharan Africa / Statistical Model / Mechanism of action / Host Range / Biological activity / Plasmodium Vivax / Treatment Effect / Female / Animals / Drug Resistance / Male / Animal Model / South America / Animal Experimentation / In Vivo / Antimalarials / Rhesus macaques / Antimicrobial agents / Macaca Mulatta / Sub Saharan Africa / Statistical Model / Mechanism of action / Host Range / Biological activity / Plasmodium Vivax / Treatment Effect

Medicinal plants from the “Sierra de Comechingones”, Argentina

Ethnobotany / Complementary and Alternative Medicine / Traditional Medicine / Health Care / Plant Biology / Argentina / Ethnopharmacology / Pharmacognosy / Medicinal Plants / Cultural Diversity / Herbal Medicine / Insecticides / Humans / Animals / Endemic species / Native Plants / Plant extracts / Antifungal Agents / Biological activity / Medicinal Plant / Biological Activities / Argentina / Ethnopharmacology / Pharmacognosy / Medicinal Plants / Cultural Diversity / Herbal Medicine / Insecticides / Humans / Animals / Endemic species / Native Plants / Plant extracts / Antifungal Agents / Biological activity / Medicinal Plant / Biological Activities

LTA4 hydrolase in human skin: decreased activity, but normal concentration in lesional psoriatic skin

Pathology / Immunohistochemistry / Humans / Animals / Skin / Psoriasis / Epidermis / Clinical Sciences / Biological activity / Rabbits / Lymphocytes / Mediator / Psoriasis / Epidermis / Clinical Sciences / Biological activity / Rabbits / Lymphocytes / Mediator

A novel sesquiterpene lactone from Centaurea pullata: Structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties

Organic Chemistry / Prediction / Pharmacokinetics / Pharmacognosy / Magnetic Resonance Spectroscopy / Structural Analysis / Cell line / In Vitro / Antimicrobial activity / Antifungal Activity / Sesquiterpenes / Antibacterial activity / Isolation / Structure Elucidation / Anti-Bacterial Agents / Water Solubility / ADME / Bioorganic and medicinal Chemistry / Biological activity / Structure activity Relationship / Microbial Viability / Centaurea / Lactones / Computational Method / Molecular Structure / Terpenoid / Structural Analysis / Cell line / In Vitro / Antimicrobial activity / Antifungal Activity / Sesquiterpenes / Antibacterial activity / Isolation / Structure Elucidation / Anti-Bacterial Agents / Water Solubility / ADME / Bioorganic and medicinal Chemistry / Biological activity / Structure activity Relationship / Microbial Viability / Centaurea / Lactones / Computational Method / Molecular Structure / Terpenoid

A novel sesquiterpene lactone from Centaurea pullata : Structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties

Organic Chemistry / Prediction / Pharmacokinetics / Pharmacognosy / Magnetic Resonance Spectroscopy / Structural Analysis / Cell line / In Vitro / Antimicrobial activity / Antifungal Activity / Sesquiterpenes / Antibacterial activity / Isolation / Structure Elucidation / Anti-Bacterial Agents / Water Solubility / ADME / Bioorganic and medicinal Chemistry / Biological activity / Structure activity Relationship / Microbial Viability / Centaurea / Lactones / Computational Method / Molecular Structure / Terpenoid / Structural Analysis / Cell line / In Vitro / Antimicrobial activity / Antifungal Activity / Sesquiterpenes / Antibacterial activity / Isolation / Structure Elucidation / Anti-Bacterial Agents / Water Solubility / ADME / Bioorganic and medicinal Chemistry / Biological activity / Structure activity Relationship / Microbial Viability / Centaurea / Lactones / Computational Method / Molecular Structure / Terpenoid
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