Biological activity

Viral Preprotoxin Signal Sequence Allows Efficient Secretion of Green Fluorescent Protein by Candida glabrata, Pichia pastoris, Saccharomyces cerevisiae, and Schizosaccharomyces pombe

Fluorescence Microscopy / Cell Biology / Multidisciplinary / Saccharomyces cerevisiae / Secretory Pathway / Mycotoxins / Protein Secretion / Applied Environmental Microbiology / Pichia pastoris / Green Fluorescent Protein / Schizosaccharomyces Pombe / Candida Glabrata / Yeasts / Gel electrophoresis / Biological activity / Culture Media / Recombinant Protein / Polyacrylamide Gel Electrophoresis / Recombinant Proteins / Full Length Movies / Mycotoxins / Protein Secretion / Applied Environmental Microbiology / Pichia pastoris / Green Fluorescent Protein / Schizosaccharomyces Pombe / Candida Glabrata / Yeasts / Gel electrophoresis / Biological activity / Culture Media / Recombinant Protein / Polyacrylamide Gel Electrophoresis / Recombinant Proteins / Full Length Movies

In Vitro and in Vivo Killing of Acute Lymphoblastic Leukemia Cells by L-Asparaginase1

Cancer / Flow Cytometry / Prediction / Treatment / Cytotoxicity / Cell Culture / In Vitro / Bone marrow / Enzyme / In Vivo / Biological activity / Cell Surface Markers / Propidium Iodide / Acute Lymphoblastic Leukemia / Cell Culture / In Vitro / Bone marrow / Enzyme / In Vivo / Biological activity / Cell Surface Markers / Propidium Iodide / Acute Lymphoblastic Leukemia

Identification of progastrin derived peptides in colorectal carcinoma extracts

Humans / Peptides / Clinical Sciences / Gut / Biological activity / Amino Acid Sequence / Radioimmunoassay / Amino Acid Sequence / Radioimmunoassay

Peptide Design Aided by Neural Networks:  Biological Activity of Artificial Signal Peptidase I Cleavage Sites †

Biochemistry / Membrane Proteins / Neural Network / Sequence Analysis / Protein Engineering / Biological activity / Amino Acid Sequence / Base Sequence / Hydrolysis / Biochemistry and cell biology / Biological activity / Amino Acid Sequence / Base Sequence / Hydrolysis / Biochemistry and cell biology

Novel type I interferon IL-28A suppresses hepatitis C viral RNA replication

Microbiology / Medical Microbiology / Virology / Hepatitis C / Cell Culture / Signal Transduction / Cell line / Humans / Animals / Human Genome / Viral Infection / Interleukins / Side Effect / Biological activity / Base Sequence / Antiviral Activity / chronic hepatitis C / Antiviral Agents / Interleukin / Interferon Alpha / Synergistic effect / Signal Transduction / Cell line / Humans / Animals / Human Genome / Viral Infection / Interleukins / Side Effect / Biological activity / Base Sequence / Antiviral Activity / chronic hepatitis C / Antiviral Agents / Interleukin / Interferon Alpha / Synergistic effect

Aza-bicyclic amino acid sulfonamides as α4β1/α4β7 integrin antagonists

Organic Chemistry / Amino Acid Profile / Conformational Analysis / Biological activity

New vasorelaxant indole alkaloids, villocarines A–D from Uncaria villosa

Organic Chemistry / Calcium / Pharmacognosy / Magnetic Resonance Spectroscopy / Structural Analysis / In Vitro / Endothelial Cells / Nitric oxide / Animals / Calcium channels / Potassium / Isolation / Rats / Endothelial cell / Rat / Voltage-Gated Potassium Channels / Molecular Conformation / Bioorganic and medicinal Chemistry / Biological activity / Uncaria / Aorta / Indole Alkaloids / Plant Leaves / In Vitro / Endothelial Cells / Nitric oxide / Animals / Calcium channels / Potassium / Isolation / Rats / Endothelial cell / Rat / Voltage-Gated Potassium Channels / Molecular Conformation / Bioorganic and medicinal Chemistry / Biological activity / Uncaria / Aorta / Indole Alkaloids / Plant Leaves

In Vitro and in Vivo Killing of Acute Lymphoblastic Leukemia Cells by L-Asparaginase1

Cancer / Flow Cytometry / Prediction / Treatment / Cytotoxicity / Cell Culture / In Vitro / Bone marrow / Enzyme / In Vivo / Biological activity / Cell Surface Markers / Propidium Iodide / Acute Lymphoblastic Leukemia / Cell Culture / In Vitro / Bone marrow / Enzyme / In Vivo / Biological activity / Cell Surface Markers / Propidium Iodide / Acute Lymphoblastic Leukemia

Biological activities of extracts from endophytic fungi isolated from Garcinia plants

Immunology / Medical Microbiology / Fungi / Antioxidants / Cercopithecus aethiops / Cell line / Humans / Animals / Endophytic Fungi / Antimalarials / Biological activity / Antineoplastic Agents / Antiviral Agents / Cell line / Humans / Animals / Endophytic Fungi / Antimalarials / Biological activity / Antineoplastic Agents / Antiviral Agents

Polysaccharide labelling: impact on structural and biological properties

Organic Chemistry / Nuclear Magnetic Resonance / Structural Properties / Food Sciences / Molecular weight / Chemical Composition / Biological activity / Chemical Treatment / Carbohydrate / Carbohydrate Polymers / Chemical Composition / Biological activity / Chemical Treatment / Carbohydrate / Carbohydrate Polymers

Novel fungicidal benzylsulfanyl-phenylguanidines

Organic Chemistry / Caenorhabditis elegans / Biofilm / Animals / Sulfides / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure

Biological characterization of a novel mammalian antimicrobial peptide

Kinetics / Biological Sciences / Spleen / Sequence alignment / Circular Dichroism / Escherichia coli / Gram Positive / Animals / Antimicrobial activity / Male / Physical sciences / Proteins / tESTIS / Antimicrobial Peptide / Cattle / Neutrophils / Spectrum / Gram-negative bacteria / Anti-Bacterial Agents / Secondary Structure / Western blot / Microbial Sensitivity Tests / Biological activity / Amino Acid Sequence / Biochemistry and cell biology / Escherichia coli / Gram Positive / Animals / Antimicrobial activity / Male / Physical sciences / Proteins / tESTIS / Antimicrobial Peptide / Cattle / Neutrophils / Spectrum / Gram-negative bacteria / Anti-Bacterial Agents / Secondary Structure / Western blot / Microbial Sensitivity Tests / Biological activity / Amino Acid Sequence / Biochemistry and cell biology

Leishmanicidal activity of benzophenones and extracts from Garcinia brasiliensis Mart. fruits

Complementary and Alternative Medicine / Plant Biology / Leishmania / Phytomedicine / Phytotherapy / Leishmaniasis / Developing Country / Mice / Animals / Fruit / Benzophenones / Silica Gel / Ethyl Acetate / Plant extracts / Health Problems / Biological activity / Structure activity Relationship / Leishmaniasis / Developing Country / Mice / Animals / Fruit / Benzophenones / Silica Gel / Ethyl Acetate / Plant extracts / Health Problems / Biological activity / Structure activity Relationship

An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity

Tourism Studies / Enzyme Inhibitors / Cannabinoids / Spleen / Cell line / Hypothermia / Mice / Female / Animals / European / Fatty Acid / Gas Chromatography/mass Spectrometry / Biological activity / Endocannabinoids / Hydrolysis / Ligands / Pain Measurement / Motor Behavior / Analgesics / Adenylyl Cyclase / Cannabinoid Receptor / Motor activity / Hypothermia / Mice / Female / Animals / European / Fatty Acid / Gas Chromatography/mass Spectrometry / Biological activity / Endocannabinoids / Hydrolysis / Ligands / Pain Measurement / Motor Behavior / Analgesics / Adenylyl Cyclase / Cannabinoid Receptor / Motor activity
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