Biological activity

Anticlastogenic activity exhibited by botryosphaeran, a new exopolysaccharide produced by Botryosphaeria rhodina MAMB-05

Mutation / Mice / Female / Animals / Male / Bone marrow / Glucans / Body Weight / Biological activity / Ascomycota / Biological Macromolecules / Mutagens / Biochemistry and cell biology / Bone marrow / Glucans / Body Weight / Biological activity / Ascomycota / Biological Macromolecules / Mutagens / Biochemistry and cell biology

Estrone derived steroidal diepoxide: Biologically active compound and precursor of a stable steroidal A,B-spiro system

STEROIDS / Cell line / Humans / Mice / Animals / Clinical Sciences / Ambient Temperature / Cell Proliferation / Biological activity / Antineoplastic Agents / estrone / Clinical Sciences / Ambient Temperature / Cell Proliferation / Biological activity / Antineoplastic Agents / estrone

An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity

Tourism Studies / Enzyme Inhibitors / Cannabinoids / Spleen / Cell line / Hypothermia / Mice / Female / Animals / European / Fatty Acid / Gas Chromatography/mass Spectrometry / Biological activity / Endocannabinoids / Hydrolysis / Ligands / Pain Measurement / Motor Behavior / Analgesics / Adenylyl Cyclase / Cannabinoid Receptor / Motor activity / Hypothermia / Mice / Female / Animals / European / Fatty Acid / Gas Chromatography/mass Spectrometry / Biological activity / Endocannabinoids / Hydrolysis / Ligands / Pain Measurement / Motor Behavior / Analgesics / Adenylyl Cyclase / Cannabinoid Receptor / Motor activity

7-[1H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors: Design, synthesis, and biological activity

Organic Chemistry / Mice / Animals / Drug Design / Kinase inhibitor / Bioorganic and medicinal Chemistry / Biological activity / Aurora kinases / Structure activity Relationship / Molecular Structure / Vascular endothelial growth factor receptor / Bioorganic and medicinal Chemistry / Biological activity / Aurora kinases / Structure activity Relationship / Molecular Structure / Vascular endothelial growth factor receptor

Leishmanicidal activity of benzophenones and extracts from Garcinia brasiliensis Mart. fruits

Complementary and Alternative Medicine / Plant Biology / Leishmania / Phytomedicine / Phytotherapy / Leishmaniasis / Developing Country / Mice / Animals / Fruit / Benzophenones / Silica Gel / Ethyl Acetate / Garcinia kola / Plant extracts / Health Problems / Biological activity / Structure activity Relationship / Leishmaniasis / Developing Country / Mice / Animals / Fruit / Benzophenones / Silica Gel / Ethyl Acetate / Garcinia kola / Plant extracts / Health Problems / Biological activity / Structure activity Relationship

In-vitro activity of essential oils, in particular Melaleuca alternifolia (tea tree) oil and tea tree oil products, against Candida spp

Microbiology / Medical Microbiology / Pharmacognosy / Essential Oil / Tea tree oil / In Vitro / Humans / Female / Candida / Antimicrobial chemotherapy / Antimicrobial / Antifungal Agents / Microbial Sensitivity Tests / Biological activity / Culture Media / Plant Oils / Minimum inhibitory concentration / Thallophyta / In Vitro / Humans / Female / Candida / Antimicrobial chemotherapy / Antimicrobial / Antifungal Agents / Microbial Sensitivity Tests / Biological activity / Culture Media / Plant Oils / Minimum inhibitory concentration / Thallophyta

Jatropha Diterpenes: a Review

Chemical Engineering / Cytotoxicity / Pharmaceutical industry / Antimicrobial activity / Spectrum / Cytotoxic Activity / Biological activity / Cytotoxic / Phorbol ester / Chemical Structure / Cytotoxic Activity / Biological activity / Cytotoxic / Phorbol ester / Chemical Structure

Jatropha Diterpenes: a Review

Chemical Engineering / Cytotoxicity / Pharmaceutical industry / Antimicrobial activity / Spectrum / Cytotoxic Activity / Biological activity / Cytotoxic / Phorbol ester / Chemical Structure / Cytotoxic Activity / Biological activity / Cytotoxic / Phorbol ester / Chemical Structure

Efficacies of KY62 against Leishmania amazonensis and Leishmania donovani in experimental murine cutaneous leishmaniasis and visceral leishmaniasis

Microbiology / Medical Microbiology / In Vitro / Toxicity / Mice / Female / Animals / Visceral Leishmaniasis / Success Rate / Antimicrobial agents / Antifungal Agents / Body Weight / Cutaneous Leishmaniasis / Water soluble polymers / Side Effect / Biological activity / Female / Animals / Visceral Leishmaniasis / Success Rate / Antimicrobial agents / Antifungal Agents / Body Weight / Cutaneous Leishmaniasis / Water soluble polymers / Side Effect / Biological activity

Crystal structure of staphylococcal enterotoxin B, a superantigen

Multidisciplinary / Nature / T cell receptor / Crystal structure / Enterotoxins / Animals / Staphylococcus aureus / Protein Secondary Structure Prediction / X ray diffraction / Protein Conformation / Biological activity / Binding Site / STAPHYLOCOCCAL-ENTEROTOXIN-B / Animals / Staphylococcus aureus / Protein Secondary Structure Prediction / X ray diffraction / Protein Conformation / Biological activity / Binding Site / STAPHYLOCOCCAL-ENTEROTOXIN-B

Péptidos bioactivos

Food Processing / Metabolic regulation / Functional Food / Mechanism of action / Biological activity / Functional Properties

Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

Organic Chemistry / Medicinal Chemistry / Pharmacokinetics / Macromolecular X-Ray Crystallography / Cell line / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor

Antimalarial Agents from Plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva

Complementary and Alternative Medicine / Plant Biology / Pharmacognosy / In Vitro / Animals / STEM / Araceae / Ficus / Bark / Isolation / Plant extracts / Plasmodium falciparum / Antimalarials / Biological activity / Extract / Active Ingredient / Planta / Molecular Structure / Plant Leaves / Terpenoid / STEM / Araceae / Ficus / Bark / Isolation / Plant extracts / Plasmodium falciparum / Antimalarials / Biological activity / Extract / Active Ingredient / Planta / Molecular Structure / Plant Leaves / Terpenoid
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