Amino Acid Substitution Rates - Page 5

Familial hypercholesterolaemia in Portugal

Genetics / Quality of life / Atherosclerosis / Adolescent / Portugal / Humans / Child / Mutation / Haplotypes / Cholesterol / Female / Blood sampling / Male / Life Expectancy / Pedigree / LDL-cholesterol / Clinical Sciences / Middle Aged / Adult / Coronary heart disease / Chromosome segregation / Indexation / Amino Acid Substitution Rates / Humans / Child / Mutation / Haplotypes / Cholesterol / Female / Blood sampling / Male / Life Expectancy / Pedigree / LDL-cholesterol / Clinical Sciences / Middle Aged / Adult / Coronary heart disease / Chromosome segregation / Indexation / Amino Acid Substitution Rates

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Mutant Cu/Zn-Superoxide Dismutase Associated with Amyotrophic Lateral Sclerosis Destabilizes Vascular Endothelial Growth Factor mRNA and Downregulates Its Expression

Neuroscience / Amyotrophic Lateral Sclerosis / Mice / Animals / Superoxide Dismutase / RNA-binding proteins / Amino Acid Substitution Rates / Vascular Endothelial Growth Factor / Down-Regulation / RNA-binding proteins / Amino Acid Substitution Rates / Vascular Endothelial Growth Factor / Down-Regulation

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Mutant Cu/Zn-Superoxide Dismutase Associated with Amyotrophic Lateral Sclerosis Destabilizes Vascular Endothelial Growth Factor mRNA and Downregulates Its Expression

Neuroscience / Amyotrophic Lateral Sclerosis / Mice / Animals / Superoxide Dismutase / RNA-binding proteins / Amino Acid Substitution Rates / Vascular Endothelial Growth Factor / Down-Regulation / RNA-binding proteins / Amino Acid Substitution Rates / Vascular Endothelial Growth Factor / Down-Regulation

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Bacterial persistence increases as environmental fitness decreases

Microbiology / Microbial biotechnology / Microbial Biotechnology / Escherichia coli / Microbial / Microarray Analysis / Amino Acid Substitution Rates / Microbial Viability / Acids / Oxidants / Gene expression profiling / Microarray Analysis / Amino Acid Substitution Rates / Microbial Viability / Acids / Oxidants / Gene expression profiling

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Systematic amino acid substitutions improved efficiency of GD2-peptide mimotope vaccination against neuroblastoma

Cancer Vaccines / Humans / Mice / Female / Animals / Neuroblastoma / Molecular Mimicry / Amino Acid Substitution Rates / Gangliosides / immunoglobulin G / Neuroblastoma / Molecular Mimicry / Amino Acid Substitution Rates / Gangliosides / immunoglobulin G

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Ultrastructural protein zero expression in Charcot-Marie-Tooth type 1B Disease

Electrophysiology / Immunohistochemistry / Biopsy / Humans / Female / Middle Aged / CHarcot Marie Tooth / Amino Acid Substitution Rates / Charcot Marie Tooth Disease / Myelin Sheath / Middle Aged / CHarcot Marie Tooth / Amino Acid Substitution Rates / Charcot Marie Tooth Disease / Myelin Sheath

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ABO(H) Blood Group A and B Glycosyltransferases Recognize Substrate via Specific Conformational Changes

Catalysis / Biological Chemistry / Biological Sciences / Humans / Blood groups / Biological / CHEMICAL SCIENCES / Hydrogen Bonding / Protein Secondary Structure Prediction / Substrate Specificity / Amino Acid Substitution Rates / Conformational Change / Biological / CHEMICAL SCIENCES / Hydrogen Bonding / Protein Secondary Structure Prediction / Substrate Specificity / Amino Acid Substitution Rates / Conformational Change

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Sequence comparison and environmental adaptation of a bacterial endonuclease

Computational Biology / Molecular Evolution / Statistical Analysis / Brackish Water / Sequence Analysis / Biological Sciences / Sequence alignment / Bacteria / Temperature / Sample Size / Enzyme / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Model System / Surface Properties / Low Temperature / Protein Conformation / Amino Acid Sequence / Amino Acid Substitution Rates / Salts / Biology Chemistry / Protein Data Bank / Isoelectric point / Biological Sciences / Sequence alignment / Bacteria / Temperature / Sample Size / Enzyme / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Model System / Surface Properties / Low Temperature / Protein Conformation / Amino Acid Sequence / Amino Acid Substitution Rates / Salts / Biology Chemistry / Protein Data Bank / Isoelectric point

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ABO(H) Blood Group A and B Glycosyltransferases Recognize Substrate via Specific Conformational Changes

Catalysis / Biological Chemistry / Biological Sciences / Humans / Blood groups / Biological / CHEMICAL SCIENCES / Hydrogen Bonding / Protein Secondary Structure Prediction / Substrate Specificity / Amino Acid Substitution Rates / Conformational Change / Biological / CHEMICAL SCIENCES / Hydrogen Bonding / Protein Secondary Structure Prediction / Substrate Specificity / Amino Acid Substitution Rates / Conformational Change

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A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815

Immunopharmacology / Mice / Female / Animals / Male / Polymerase Chain Reaction / Molecular cloning / Model System / Major histocompatibility complex / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Sensitivity and Specificity / Antineoplastic Agents / MHC class I / Nucleotides / Cytotoxic T cells / Polymerase Chain Reaction / Molecular cloning / Model System / Major histocompatibility complex / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Sensitivity and Specificity / Antineoplastic Agents / MHC class I / Nucleotides / Cytotoxic T cells

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A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815

Immunopharmacology / Mice / Female / Animals / Male / Polymerase Chain Reaction / Molecular cloning / Model System / Major histocompatibility complex / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Sensitivity and Specificity / Antineoplastic Agents / MHC class I / Nucleotides / Cytotoxic T cells / Polymerase Chain Reaction / Molecular cloning / Model System / Major histocompatibility complex / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Sensitivity and Specificity / Antineoplastic Agents / MHC class I / Nucleotides / Cytotoxic T cells

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Identification of amino acid residues participating in the energy coupling and proton transport of Streptomyces coelicolor A3(2) H+-pyrophosphatase

Membrane Proteins / Energy Conversion / Energy Metabolism / Biological Sciences / Streptomyces coelicolor / Physical sciences / Amino Acids / Energy efficient / Amino Acid Sequence / Amino Acid Substitution Rates / Protons / Biochemistry and cell biology / Physical sciences / Amino Acids / Energy efficient / Amino Acid Sequence / Amino Acid Substitution Rates / Protons / Biochemistry and cell biology

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Functional Characterization of Candida albicans ABC Transporter Cdr1p

Fluorescent Dyes and Reagents / Confocal Microscopy / Biological Sciences / Saccharomyces cerevisiae / Drug Resistance / P-glycoprotein / Candida albicans / Monoclonal Antibodies / Green Fluorescent Protein / Substrate Specificity / Microbial Sensitivity Tests / Genetic variation / Amino Acid Sequence / Amino Acid Substitution Rates / Fusion Protein / Site-directed Mutagenesis / Plasma Membrane / Binding Site / Eukaryotic Cell / Cycloheximide / P-glycoprotein / Candida albicans / Monoclonal Antibodies / Green Fluorescent Protein / Substrate Specificity / Microbial Sensitivity Tests / Genetic variation / Amino Acid Sequence / Amino Acid Substitution Rates / Fusion Protein / Site-directed Mutagenesis / Plasma Membrane / Binding Site / Eukaryotic Cell / Cycloheximide

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Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux

Microbiology / Medical Microbiology / Multidrug Resistance / Candida albicans / Antimicrobial chemotherapy / Ketoconazole / Membrane transport proteins / Protein Secondary Structure Prediction / Substrate Specificity / Antifungal Agents / Amino Acid Profile / Efflux Pumps / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Site-directed Mutagenesis / Ketoconazole / Membrane transport proteins / Protein Secondary Structure Prediction / Substrate Specificity / Antifungal Agents / Amino Acid Profile / Efflux Pumps / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Site-directed Mutagenesis

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Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities

Catalysis / Kinetics / DNA replication / Biological Sciences / Environmental Sciences / Humans / Mutagenesis / Mutation / Nucleic Acids / Multienzyme complexes / Amino Acid Sequence / Amino Acid Substitution Rates / Structure activity Relationship / Humans / Mutagenesis / Mutation / Nucleic Acids / Multienzyme complexes / Amino Acid Sequence / Amino Acid Substitution Rates / Structure activity Relationship

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A Replication-Competent, Neutralization-Sensitive Variant of Simian Immunodeficiency Virus Lacking 100 Amino Acids of Envelope

Kinetics / Virology / Biological Sciences / Humans / Cell fusion / Animals / Membrane Fusion / P-glycoprotein / T lymphocytes / Complexity Analysis / Amino Acid Profile / Transfection / Simian Immunodeficiency Virus / Amino Acid Sequence / Amino Acid Substitution Rates / Animals / Membrane Fusion / P-glycoprotein / T lymphocytes / Complexity Analysis / Amino Acid Profile / Transfection / Simian Immunodeficiency Virus / Amino Acid Sequence / Amino Acid Substitution Rates

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