Amino Acid Substitution Rates

A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan

Medical Microbiology / Pakistan / Malaria / Adolescent / Humans / Child / Female / Drug Resistance / Male / Polymerase Chain Reaction / Young Adult / Infant / Gene Dosage / Aged / Middle Aged / Genotype / Adult / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Substitution Rates / Child / Female / Drug Resistance / Male / Polymerase Chain Reaction / Young Adult / Infant / Gene Dosage / Aged / Middle Aged / Genotype / Adult / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Substitution Rates

Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo

Molecular endocrinology / Molecular / Enzymes / Insulin / Glucagon / Mice / cyclic AMP / Animals / Enzyme / Clinical Sciences / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Veterinary Sciences / Mechanism of action / Biological activity / Amino Acid Substitution Rates / Type 2 Diabetes Mellitus / Mice / cyclic AMP / Animals / Enzyme / Clinical Sciences / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Veterinary Sciences / Mechanism of action / Biological activity / Amino Acid Substitution Rates / Type 2 Diabetes Mellitus

Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease

Cognitive Science / Neurology / Humans / Haplotypes / Female / Male / Clinical Sciences / Aged / Middle Aged / Adult / Internationality / Arginine / Cysteine / Glycine / Amino Acid Substitution Rates / Neurosciences / Parkinson Disease / Male / Clinical Sciences / Aged / Middle Aged / Adult / Internationality / Arginine / Cysteine / Glycine / Amino Acid Substitution Rates / Neurosciences / Parkinson Disease

A new case of ALG8 deficiency (CDG Ih)

Humans / Optic Nerve / Female / Infant / Clinical Sciences / Newborn Infant / Fatty Liver / Liver Disease / Amino Acid Substitution Rates / Newborn Infant / Fatty Liver / Liver Disease / Amino Acid Substitution Rates

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Mitochondria / Gene expression / Biological Sciences / Phylogeny / Environmental Sciences / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport

A Picomolar Inhibitor of Resistant Strains of Human Immunodeficiency Virus Protease Identified by a Combinatorial Approach

Kinetics / Mutation / HIV protease / Drug Resistance / Drug Design / Enzyme / Human immunodeficiency virus / Protease Inhibitors / Substrate Specificity / Amino Acid Profile / Amino Acid Substitution Rates / Biochemistry and cell biology / Enzyme / Human immunodeficiency virus / Protease Inhibitors / Substrate Specificity / Amino Acid Profile / Amino Acid Substitution Rates / Biochemistry and cell biology

WNT4 deficiency--a clinical phenotype distinct from the classic Mayer-Rokitansky-Kuster-Hauser syndrome: A Case Report

Adolescent / Case Report / Humans / Child / Sequence alignment / Kidney / Female / Infant / Sex Determination / Phenotype / Human reproduction / Adult / Amino Acid Sequence / Ovary / Amino Acid Substitution Rates / Sexual Differentiation / Uterus / Syndrome / Kidney / Female / Infant / Sex Determination / Phenotype / Human reproduction / Adult / Amino Acid Sequence / Ovary / Amino Acid Substitution Rates / Sexual Differentiation / Uterus / Syndrome

L-Ilf3 and L-NF90 Traffic to the Nucleolus Granular Component: Alternatively-Spliced Exon 3 Encodes a Nucleolar Localization Motif

Multidisciplinary / Humans / Alternative splicing / PLoS one / HeLa cells / Alternative Splicing / Protein isoforms / Amino Acid Sequence / Amino Acid Substitution Rates / fluorescence recovery after photobleaching (FRAP) / Subcellular Fractions / Protein Transport / Alternative Splicing / Protein isoforms / Amino Acid Sequence / Amino Acid Substitution Rates / fluorescence recovery after photobleaching (FRAP) / Subcellular Fractions / Protein Transport

Differences in Fcgamma receptor IIa genotypes and IgG subclass pattern of anti-malarial antibodies between sympatric ethnic groups in Mali

Polymorphism / Medical Microbiology / Malaria / Adolescent / Disease susceptibility / Mali / Humans / Child / Female / Male / Infant / Ethnic Groups / Middle Aged / Cellular Immunity / Adult / Ethnic Group / Amino Acid Profile / Amino Acid Substitution Rates / Enzyme Linked Immunosorbent Assay / Fc Receptor / immunoglobulin G / Mali / Humans / Child / Female / Male / Infant / Ethnic Groups / Middle Aged / Cellular Immunity / Adult / Ethnic Group / Amino Acid Profile / Amino Acid Substitution Rates / Enzyme Linked Immunosorbent Assay / Fc Receptor / immunoglobulin G

Identification of a Mouse Short-chain Dehydrogenase/Reductase Gene, Retinol Dehydrogenase-similar: FUNCTION OF NON-CATALYTIC AMINO ACID RESIDUES IN ENZYME ACTIVITY

Kinetics / Biological Chemistry / Biological Sciences / Kidney / Liver / Mice / Animals / CHEMICAL SCIENCES / Molecular cloning / Substrate Specificity / Protein Conformation / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Mice / Animals / CHEMICAL SCIENCES / Molecular cloning / Substrate Specificity / Protein Conformation / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates

Mutagenesis of Specific Amino Acids Converts Carnitine Acetyltransferase into Carnitine Palmitoyltransferase †

Biochemistry / Kinetics / Molecular modeling / Animals / Amino Acids / Radiometry / Rats / Substrate Specificity / Amino Acid Profile / Amino Acid Sequence / In Silico / Amino Acid Substitution Rates / Fluorometry / Biochemistry and cell biology / Radiometry / Rats / Substrate Specificity / Amino Acid Profile / Amino Acid Sequence / In Silico / Amino Acid Substitution Rates / Fluorometry / Biochemistry and cell biology

ACAP1 Promotes Endocytic Recycling by Recognizing Recycling Sorting Signals

Fluorescence Microscopy / Fluorescent Dyes and Reagents / Western blotting / Biological Sciences / Humans / Endocytosis / Animals / HeLa cells / Glutathione Transferase / Alanine / Amino Acid Sequence / Amino Acid Substitution Rates / Organic Chemicals / Endocytosis / Animals / HeLa cells / Glutathione Transferase / Alanine / Amino Acid Sequence / Amino Acid Substitution Rates / Organic Chemicals

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Mitochondria / Gene expression / Biological Sciences / Phylogeny / Environmental Sciences / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport

Differences in Fcgamma receptor IIa genotypes and IgG subclass pattern of anti-malarial antibodies between sympatric ethnic groups in Mali

Polymorphism / Medical Microbiology / Malaria / Adolescent / Disease susceptibility / Mali / Humans / Child / Female / Male / Infant / Ethnic Groups / Middle Aged / Cellular Immunity / Adult / Ethnic Group / Amino Acid Profile / Amino Acid Substitution Rates / Enzyme Linked Immunosorbent Assay / Fc Receptor / immunoglobulin G / Mali / Humans / Child / Female / Male / Infant / Ethnic Groups / Middle Aged / Cellular Immunity / Adult / Ethnic Group / Amino Acid Profile / Amino Acid Substitution Rates / Enzyme Linked Immunosorbent Assay / Fc Receptor / immunoglobulin G

Molecular Evolution in Large Genetic Networks: Does Connectivity Equal Constraint?

Evolutionary Biology / Genetics / Molecular Evolution / Cell Cycle / Energy Metabolism / Saccharomyces cerevisiae / Molecular / Escherichia coli / Power Law / Cellular Network / Evolutionary rate / Protein Interaction / Evolutionary Constraint / Amino Acid Substitution Rates / Likelihood Functions / Biochemistry and cell biology / Saccharomyces cerevisiae / Molecular / Escherichia coli / Power Law / Cellular Network / Evolutionary rate / Protein Interaction / Evolutionary Constraint / Amino Acid Substitution Rates / Likelihood Functions / Biochemistry and cell biology

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Mitochondria / Gene expression / Biological Sciences / Phylogeny / Environmental Sciences / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport
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