Selenomethionine reduces visual deficits due to developmental methylmercury exposures

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Selenomethionine reduces visual deficits due to developmental methylmercury exposures ARTICLE in PHYSIOLOGY & BEHAVIOR · FEBRUARY 2008 Impact Factor: 2.98 · DOI: 10.1016/j.physbeh.2007.08.023 · Source: PubMed

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6 AUTHORS, INCLUDING: Daniel N Weber

Victoria P Connaughton

University of Wisconsin - Milwaukee

American University Washington D.C.

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Michael Carvan University of Wisconsin - Milwaukee 53 PUBLICATIONS 1,244 CITATIONS SEE PROFILE

Available from: Michael Carvan Retrieved on: 05 February 2016

NIH Public Access Author Manuscript Physiol Behav. Author manuscript; available in PMC 2009 January 28.

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Published in final edited form as: Physiol Behav. 2008 January 28; 93(1-2): 250–260.

Selenomethionine reduces visual deficits due to developmental methylmercury exposures Daniel N. Weber1, Victoria P. Connaughton2, John A. Dellinger3, David Klemer4, Ava Udvadia5,6, and Michael J. Carvan III6 1Marine and Freshwater Biomedical Sciences Center, University of Wisconsin-Milwaukee 2Department of Biology, American University, Washington, DC 3School of Health Sciences, University of Wisconsin-Milwaukee 4Department of Electrical Engineering, University of Wisconsin-Milwaukee 5Department of Biological Sciences, University of Wisconsin-Milwaukee

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6Great Lakes WATER Institute, University of Wisconsin-Milwaukee

Abstract

NIH-PA Author Manuscript

Developmental exposures to methylmercury (MeHg) have life-long behavioral effects. Many micronutrients, including selenium, are involved in cellular defenses against oxidative stress and may reduce the severity of MeHg-induced deficits. Zebrafish embryos (