PP-278. Iron deficiency in late preterm infants

Abstracts

Conclusions Budin focused his interest on infant mortality rates and he was able to suggest the mothers the way how insuring adequate growth and nutrition to their infants.

doi:10.1016/j.earlhumdev.2010.09.331

PP-276. Management of congenital diaphragmatic hernia (CDH) during the last 10 years in a tertiary referral neonatal and surgical center Jakub Behrendta, Magdalena Kwiatkowska-Grucaa, Klaudia Dabrowskab, Dorota Kuhnya, Anna Krola, Wojciech Korlackib, Urszula Godula-Stuglika a NICU Zabrze, Department of Pediatrics, Silesian Medical University, Poland b Department of Pediatric Surgery Zabrze, Silesian Medical University, Poland Aim CDH is severe defect that occurs sporadically with incidence of 1:2500 live birth, unknown pathogenesis and high mortality (30–50%). Survival is dependent on availability of prenatal diagnosis, resuscitation, modes of respiratory assistance, NO, ECMO and definitive surgical intervention in referral centre. Aim. Assessment of results of treatment results of CDH in neonates according to the their gestational age, birth asphyxia and day of life in which diagnosis was stated. Materials and methods Within 10 years (2000–2009) 20 (13 males, 7 females) newborns with mean GA 38.6 weeks (13 full-term, 7 prematures), all with perinatal risk factors, 4 with severe birth asphyxia (Apgar ≤3) were born with CDH; 3: R-CDH, 11: typical L-CDH, 4 — defect of posterior part of diaphragm, 2 — absent of lip of posterior part of diaphragm. Results Prenatal diagnosis of CDH only in 1 case was stated; in others cases between 1st and 4th day of life: in 6 in first referral neonatal unit, in 7 in NICU without surgery, in 6 in NICU with surgical center. PPNH in 6 (3 died) were diagnosed. Surgical repair was made on first day of life in 1 neonate, in 3 — on second, in 12 — on third and in 4 — on 4–5th day of life. Mechanical ventilation (mean 24 days), dopamine and total parenteral nutrition (mean 21 days) were necessary in all babies. Hypoplastic lung in 4 (3 died) neonates was diagnosed. Five neonates died, among them 2 prematures and 2 SGA, all with birth asphyxia and vaginally born. Total survival of 55%, neurodevelopment disorders of 15% (hydrocephalus 1, BPD – 1), and postoperative relaxation of diaphragma of 1 baby were noted. Conclusions Birth asphyxia, LBW, lung hypoplasia connected with delayed diagnosis of CDH are factors of bad prognosis in the management of CDH in neonates. doi:10.1016/j.earlhumdev.2010.09.332

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PP-277. Determinants of perinatal mortality in Prilep General Hospital Gabriela Tavcioskaa, Blaga Kocoskaa, Anet Papazovska-Cherepnalkovskib a General Hospital Prilep, Department of Neonatology, Republic of Macedonia b University Children's Hospital, Department of Neonatology, Republic of Macedonia Aim Perinatal mortality which includes stillbirths and neonatal deaths in the first week of life is an important indicator for quality of health care. Perinatal mortality in low income countries such as Macedonia still remains a public health problem. Aims: to evaluate the perinatal mortality rate over a four years period (2004–2008) in Prilep General Hospital (secondary level of health care), to compare with national perinatal mortality rate in that period and to present data collected retrospectively about the risk factors for perinatal deaths. Materials and methods We analyzed data related to mother, child and obstetric care in the period from 2004 to 2008. Data were collected from medical histories of the mothers and their newborns who died in our hospital or at the University Children's Hospital after being transported according to medical indications. Results Perinatal mortality rate was 15.8/1000 births in 2004; 10.0/1000 births in 2005; 18.6/1000 births in 2006; 17.9/1000 births in 2007 and 13.1/1000 births in 2008.Out of the total infant deaths (64), 53.1% were stillborn and 46.9% died during the first week. There were 33 (51.5%) preterm and 31 (48.4%) low birth weight babies. 21 (32.8%) deliveries were carried out by some intervention (Caesarean Section, Vacuum Extractor, Bracht). Twenty two (34.3%) mothers had none or less than 3 ultrasound examinations during pregnancy, 35 (54.6%) mothers had some health problems (infections, anemia, and gestosis). 21 (32.8%) mothers had over 30 years. Conclusions Maternal health, maternal age, antenatal visits, gestational duration, delivery type and birth weight were contributing factors in the determination of the perinatal mortality rate. This study also represents a basis for further mother and child health care programming on the local secondary level of health care.

doi:10.1016/j.earlhumdev.2010.09.333

PP-278. Iron deficiency in late preterm infants Hulya Ozdemir, Ipek Akman, Utku Demirel, Senay Coskun, Hulya Bilgen, Eren Ozek Marmara University Medical School, Department of Neonatology, Turkey Aim Iron prophylaxis is recommended at the 4th month for healthy term infants and at the end of 1st postnatal month for preterm infants born