OSTEOARTHIRITS:COMPARISON BETWEEN INTRAARTICULAR AND ORAL TREAMENT

OSTEOARTHIRITS:COMPARISON BETWEEN INTRAARTICULAR AND ORAL TREAMENT Osteoarthritis is the end result of a variety of disorders leading to the structural or functional failure of 1 or more joint, including the nearby muscles, underlying bone, ligaments, joint lining (synovium), and the joint cover capsule. It also involves an advancing loss of cartilage. Joint cartilage is a layer of tissue present at the joint surfaces that sustains joint loading and allows motion. It is gel-like, porous, and elastic. Normal cartilage provides a durable, low-friction, load-bearing surface for joints. Stationary phase of disease progression in osteoarthritis involves the formation of osteophytes or joint space narrow, later with obliteration of the joint space. The appearance of sub-chondral cysts (cysts in the bone underneath the cartilage) indicates the erosive phase of disease progression in osteoarthritis. The last phase in the disease progression involves bone repair and remodeling.