Organocatalytic synthesis of spiro compounds via a cascade Michael–Michael-aldol reaction

View this journal online at wileyonlinelibrary.com Spirocyclic compounds R 0015 DOI: 10.1002/chin.201105089 Synthesis of Spiro Compounds via a Cascade Michael— 05- 089 Organocatalytic -Michael-Aldol Reaction. — The title reaction affords spirooxindole derivatives in good yields and with high diastereo- and enantioselectivity. Moreover, the reaction sequence also works with heterocycles such as oxindoles, benzofuranones, pyrazolones, and azlactones. — (COMPANYO, X.; ZEA, A.; ALBA, A.-N. R.; MAZZANTI, A.; MOYANO, A.; RIOS*, R.; Chem. Commun. (Cambridge) 46 (2010) 37, 6953-6955, http://dx.doi.org/10.1039/c0cc01522a ; Dep. Quim. Org., Fac. Quim., Univ. Barcelona, E-08028 Barcelona, Spain; Eng.) — D. Singer

ChemInform 2011, 42, issue 01

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