La depleción de células CD34+/CD144+ en pacientes de revascularización miocárdica no está mediada por un aumento de la apoptosis inducida por el TGF-beta plasmático

June 5, 2017 | Autor: Enrique Rodriguez | Categoría: Apoptosis, Functional impairment, Transforming Growth Factor Beta, Coronary artery bypass surgery
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IntroductionCoronary atherosclerotic disease has been linked to endothelial progenitor cell (EPC) depletion and functional impairment. We assessed the number of CD34+/KDR+ and CD34+/CD144+ cells in coronary artery bypass grafting (CABG) patients, compared to valvular patients, and the apoptotic effect of the plasma from these two groups on early outgrowth cells (EOCs) from healthy donors.
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