Inmunolocalización de catepsina B en condrocitos y osteoclastos en discondroplasia (osteocondrosis) equina Immunolocalization of cathepsin B in chondrocytes and osteoclasts in equine dyschondroplasia (osteochondrosis)

The enzyme cathepsin B was immunolocalized by immunofluorescence in articular cartilage and subchon- dral bone in both normal and dyschondroplastic samples obtained from young horses aged 1-5 years old. Distribution of the enzyme was variable in dyschondropla stic cartilage due to a general lack of zonal organization. A strong intracellular immunoreaction was observed in abnormal chondrocytes arranged in clusters in