Estudio comparativo de la capacidad inmunogénica y protectogénica en hámsters de variantes de vacuna adsorbida y no adsorbida contra la leptospirosis

Comparative study of the immunogenicity and protective capability in hamsters of adsorbed and non adsorbed vaccines against leptospirosis. Two experimental vaccines based on inactivated whole cells were formulated: non adsorbed (NAV) and adsorbed in aluminium hydroxide (AV), containing 50-80x10 6 cells of serovars L. canicola, L. copenhageni and L. mozdok per 0.5 mL dose. The immunogenicity and protection were evaluated