Comparative antimicrobial activity of Acacia nilotica L. leaves extracts against Pathogenic Bacteria and Fungi

The comparative in vitro antimicrobial activity of ethanol and chloroform leaves extracts from Acacia nilotica L. was studied. Leaves extracts exhibited considerable bacteriostatic activity against two Gram-positive and three Gram-negative strains. The antimicrobial action was compared with the effect of doxycycline antibiotic. The maximum zone of inhibition of 29 mm diameter was observed in Escherichia coli with ethanol extract while a minimum 8 mm zone of inhibition was found in Bacillus subtilis. Klebsiella pneumoniae showed marked resistance towards both ethanol and chloroform extracts. Among the fungal strains tested, Aspergillus flavus exhibited maximum sensitivity action of the extracts. This analysis revealed the high antimicrobial activity in the ethanol extract of A. nilotica L. than chloroform extract. It is recommended to isolate, identify and integrate the bioactive principle in these pathogens management.