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Movement disorders
RESEARCH PAPER
Clinicoradiological comparison between vascular parkinsonism and Parkinson’s disease Thiago Cardoso Vale,1 Paulo Caramelli,2 Francisco Cardoso3 ▸ Additional material is published online only. To view please visit the journal online (http://dx.doi.org/10.1136/ jnnp-2014-307867). 1
Department of Neurology Service and Internal Medicine, Faculty of Medicine, University Hospital, Federal University of Juiz de Fora (UFJF), Juiz de Fora, Minas Gerais, Brazil 2 Cognitive and Behavioral Neurology Unit, Department of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil 3 Movement Disorders Unit, Department of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil Correspondence to Professor Francisco Cardoso, Movement Disorders Unit, Department of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais (UFMG), Avenida Pasteur 89/1107, Belo Horizonte, MG CEP 30150290, Brazil;
[email protected] Received 12 February 2014 Revised 3 June 2014 Accepted 19 June 2014 Published Online First 8 July 2014
To cite: Vale TC, Caramelli P, Cardoso F. J Neurol Neurosurg Psychiatry 2015;86: 547–553.
ABSTRACT Objective To compare the clinical and radiological features of vascular parkinsonism (VP) and Parkinson’s disease (PD). Methods Cross-sectional study where 15 patients with VP (8 (53.3%) men; aged 75.7±10.4 years) and 30 patients with PD (17 (56.7%) men; aged 67.3 ±7.5 years) underwent motor and cognitive evaluation and brain MRI. Results Patients with VP were, on average, 8.4 years older ( p=0.004); all had arterial hypertension. They presented with a sudden onset of parkinsonism (80%) and a rapidly progressive clinical course (53.3%). Predominant lower body parkinsonism ( p
