RNAi

Nucleic acid polymerases use a general acid for nucleotidyl transfer

Biochemistry / Genetics / Biophysics / Molecular Biology / RNA / M Rna Processing / Protein Folding / Catalysis / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Manganese / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / RNAi / Viruses / Chromatin remodeling / Proton Transfer / Mechanism / Macromolecules / Nucleic Acids / Proteins / Enzyme / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Amino Acids / Active site / Amino Acid Profile / Metal ion / Protons / DNA recombination / Nucleic Acid / M Rna Processing / Protein Folding / Catalysis / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Manganese / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / RNAi / Viruses / Chromatin remodeling / Proton Transfer / Mechanism / Macromolecules / Nucleic Acids / Proteins / Enzyme / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Amino Acids / Active site / Amino Acid Profile / Metal ion / Protons / DNA recombination / Nucleic Acid

Nucleic acid polymerases use a general acid for nucleotidyl transfer

Biochemistry / Genetics / Biophysics / Molecular Biology / RNA / M Rna Processing / Protein Folding / Catalysis / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Manganese / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / RNAi / Viruses / Chromatin remodeling / Proton Transfer / Mechanism / Macromolecules / Nucleic Acids / Proteins / Enzyme / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Amino Acids / Active site / Amino Acid Profile / Metal ion / Protons / DNA recombination / Nucleic Acid / M Rna Processing / Protein Folding / Catalysis / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Manganese / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / RNAi / Viruses / Chromatin remodeling / Proton Transfer / Mechanism / Macromolecules / Nucleic Acids / Proteins / Enzyme / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Amino Acids / Active site / Amino Acid Profile / Metal ion / Protons / DNA recombination / Nucleic Acid

Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis

Thermodynamics / Molecular Biology / Computational Biology / Gene Silencing / Global Analysis / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus

Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis

Thermodynamics / Molecular Biology / Computational Biology / Gene Silencing / Global Analysis / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus

A splicing regulator promotes transcriptional elongation

Biochemistry / Genetics / Biophysics / Molecular Biology / RNA / M Rna Processing / Protein Folding / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / Humans / RNAi / Animals / Chromatin remodeling / Mechanism / Macromolecules / Nucleic Acids / Proteins / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Introns / RNA-binding proteins / Ribonucleoproteins / DNA recombination / M Rna Processing / Protein Folding / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / Humans / RNAi / Animals / Chromatin remodeling / Mechanism / Macromolecules / Nucleic Acids / Proteins / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Introns / RNA-binding proteins / Ribonucleoproteins / DNA recombination

Nucleic acid polymerases use a general acid for nucleotidyl transfer

Biochemistry / Genetics / Biophysics / Molecular Biology / RNA / M Rna Processing / Protein Folding / Catalysis / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Manganese / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / RNAi / Viruses / Chromatin remodeling / Proton Transfer / Mechanism / Macromolecules / Nucleic Acids / Proteins / Enzyme / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Amino Acids / Active site / Amino Acid Profile / Metal ion / Protons / DNA recombination / Nucleic Acid / M Rna Processing / Protein Folding / Catalysis / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Manganese / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / RNAi / Viruses / Chromatin remodeling / Proton Transfer / Mechanism / Macromolecules / Nucleic Acids / Proteins / Enzyme / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Amino Acids / Active site / Amino Acid Profile / Metal ion / Protons / DNA recombination / Nucleic Acid

Nuclear transport comes full circle

Biochemistry / Genetics / Biophysics / Molecular Biology / RNA / M Rna Processing / Protein Folding / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / Humans / RNAi / Chromatin remodeling / Mechanism / Macromolecules / Nucleic Acids / Proteins / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Cell nucleus / DNA recombination / Nuclear Transport / M Rna Processing / Protein Folding / Cell Cycle / DNA replication / Cell Biology / DNA repair / Apoptosis / Gene expression / Translation / Signal Transduction / Transcription / Biological Sciences / Molecular / Humans / RNAi / Chromatin remodeling / Mechanism / Macromolecules / Nucleic Acids / Proteins / Chromatin / Chromatin structure / CHEMICAL SCIENCES / Cell nucleus / DNA recombination / Nuclear Transport

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

Gene regulation / Cancer / Gene expression / Biological Sciences / Humans / Mice / RNAi / Animals / Hepatocellular Carcinoma / Genes / Behavioral Animal Models / Mice / RNAi / Animals / Hepatocellular Carcinoma / Genes / Behavioral Animal Models
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