Quinolines - Page 3

Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison

Survival Analysis / Treatment Outcome / Adolescent / Myanmar / Humans / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk

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Effi cacy and eff ectiveness of dihydroartemisinin-piperaquine versus artesunate-mefl oquine in falciparum malaria: an open-label randomised comparison

Survival Analysis / Treatment Outcome / Adolescent / Myanmar / Humans / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk

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Biological evaluation of omega-(dialkylamino)alkyl derivatives of 6H-indolo[2,3-b]quinoline--novel cytotoxic DNA topoisomerase II inhibitors

DNA / Humans / Alkaloids / Anticancer / KB cells / Microbial Sensitivity Tests / Quinolines / Microbial Sensitivity Tests / Quinolines

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FR-190997, a nonpeptide bradykinin B2-receptor partial agonist, is a potent and efficacious intraocular pressure lowering agent in ocular hypertensive cynomolgus monkeys

Drug development / Humans / Animals / Benzophenones / Eye / Swine / Macaca fascicularis / Quinolines / Gene Expression Regulation / Ocular Hypertension / Swine / Macaca fascicularis / Quinolines / Gene Expression Regulation / Ocular Hypertension

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Multidrug Resistance (MDR1) P-glycoprotein Enhances Esterification of Plasma Membrane Cholesterol

Biological Chemistry / Biological Sciences / Progesterone / Humans / Mice / Cholesterol / Multidrug Resistance / Animals / P-glycoprotein / T cells / Esterification / CHEMICAL SCIENCES / Dehydroepiandrosterone / Quinolines / Verapamil / 4-Tetrahydroisoquinolines / Cholesterol / Multidrug Resistance / Animals / P-glycoprotein / T cells / Esterification / CHEMICAL SCIENCES / Dehydroepiandrosterone / Quinolines / Verapamil / 4-Tetrahydroisoquinolines

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Conversion of biomembrane-produced energy into electric form. I. Submitochondrial particles

Electron Microscopy / Metabolism / Membranes / Kinetics / Calcium / Mitochondria / Fluorescent Dyes and Reagents / Vibration / Biological Sciences / Permeability / Mercury / Animals / Physical sciences / Light / Plants / Potassium / Absorption / Electron Transport / Cattle / Anti-Bacterial Agents / Ascorbic Acid / Rats / Oxygen / Myocardium / Oxidative phosphorylation / Spectrum analysis / Phosphates / Energy Transfer / Cytochromes / Rabbits / Quinolines / NAD / Cyanides / Quaternary Ammonium Compounds / Organometallic Compounds / Hydrogen-Ion Concentration / Oxygen Consumption / Boron Compounds / Ions / Micrococcus luteus / Photophosphorylation / Biochemistry and cell biology / aniline Compounds / Adenosine Triphosphate / Chloroplasts / Mitochondria / Fluorescent Dyes and Reagents / Vibration / Biological Sciences / Permeability / Mercury / Animals / Physical sciences / Light / Plants / Potassium / Absorption / Electron Transport / Cattle / Anti-Bacterial Agents / Ascorbic Acid / Rats / Oxygen / Myocardium / Oxidative phosphorylation / Spectrum analysis / Phosphates / Energy Transfer / Cytochromes / Rabbits / Quinolines / NAD / Cyanides / Quaternary Ammonium Compounds / Organometallic Compounds / Hydrogen-Ion Concentration / Oxygen Consumption / Boron Compounds / Ions / Micrococcus luteus / Photophosphorylation / Biochemistry and cell biology / aniline Compounds / Adenosine Triphosphate / Chloroplasts

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Ciprofloxacin penetration into extravascular spaces in a rabbit model

Microbiology / Medical Microbiology / Female / Animals / Ciprofloxacin / Rabbits / Quinolines / Protein Binding / Extracellular Space / Blood Proteins / Rabbits / Quinolines / Protein Binding / Extracellular Space / Blood Proteins

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Experimental pneumococcal pleural empyema model: the effect of moxifloxacin

Microbiology / Medical Microbiology / Streptococcus pneumoniae / Animals / Male / Sterilization / Antimicrobial chemotherapy / Rabbits / Pasteurella Multocida / Quinolines / Turpentine / Pleura / Fluoroquinolones / Sterilization / Antimicrobial chemotherapy / Rabbits / Pasteurella Multocida / Quinolines / Turpentine / Pleura / Fluoroquinolones

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Experimental pneumococcal pleural empyema model: the effect of moxifloxacin

Microbiology / Medical Microbiology / Streptococcus pneumoniae / Animals / Male / Sterilization / Rabbits / Pasteurella Multocida / Quinolines / Turpentine / Pleura / Fluoroquinolones / Sterilization / Rabbits / Pasteurella Multocida / Quinolines / Turpentine / Pleura / Fluoroquinolones

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Poly(ADP-Ribose) Polymerase Inhibition Alleviates Experimental Diabetic Sensory Neuropathy

Diabetes / Immunohistochemistry / Oxidative Stress / Apoptosis / Blood Glucose / Animals / Male / Neurons / Rats / Body Weight / Wistar Rats / Quinolines / Hyperalgesia / Tyrosine / Animals / Male / Neurons / Rats / Body Weight / Wistar Rats / Quinolines / Hyperalgesia / Tyrosine

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Randomized, Open-Label Trial of Primaquine against Vivax Malaria Relapse in Indonesia

Microbiology / Medical Microbiology / Malaria / Indonesia / Humans / Drug Resistance / Male / Adult / Antimalarials / Combination drug therapy / Quinolines / Quinine / SECONDARY PREVENTION / Military Personnel / Plasmodium Vivax / Primaquine / Drug Resistance / Male / Adult / Antimalarials / Combination drug therapy / Quinolines / Quinine / SECONDARY PREVENTION / Military Personnel / Plasmodium Vivax / Primaquine

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Dual human epidermal growth factor receptor 2 blockade

Signal Transduction / Humans / Female / Quinolines / Molecular Targeted Therapy / Quinazolines / Clinical Trials as Topic / Quinazolines / Clinical Trials as Topic

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Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam

Tropical Medicine / Treatment / Treatment Outcome / Vietnam / Adolescent / Comparative Study / Tropical medicine (Health Sciences) / Humans / Child / Female / Therapy / Drug Resistance / Classification / Male / Young Adult / Middle Aged / Adult / Public health systems and services research / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Pilot Projects / Genotypes / Amodiaquine / Age Groups / Multiple Drug Resistance / Child preschool / Comparative Study / Tropical medicine (Health Sciences) / Humans / Child / Female / Therapy / Drug Resistance / Classification / Male / Young Adult / Middle Aged / Adult / Public health systems and services research / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Pilot Projects / Genotypes / Amodiaquine / Age Groups / Multiple Drug Resistance / Child preschool

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Resistance to a Protein Farnesyltransferase Inhibitor in Plasmodium falciparum

Malaria / Biological Chemistry / Biological Sciences / Protein-Protein Interaction / Humans / Sequence alignment / Animals / Drug Resistance / Biological / Chemical Analysis / CHEMICAL SCIENCES / Plasmodium falciparum / Enzyme activity / Protozoan Proteins / Imidazoles / Amino Acid Sequence / Quinolines / Binding Site / Molecular Structure / Molecular Sequence Data / Sequence alignment / Animals / Drug Resistance / Biological / Chemical Analysis / CHEMICAL SCIENCES / Plasmodium falciparum / Enzyme activity / Protozoan Proteins / Imidazoles / Amino Acid Sequence / Quinolines / Binding Site / Molecular Structure / Molecular Sequence Data

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Powerful Bactericidal Activity of Moxifloxacin in Human Leprosy

Microbiology / Clinical Trial / Medical Microbiology / Treatment Outcome / Humans / Leprosy / Mice / Animals / Male / Skin / Middle Aged / Anti-Bacterial Agents / Adult / Foot / Antimicrobial agents / Side Effect / Quinolines / Mycobacterium leprae / Fluoroquinolones / Bactericidal Activity / Leprosy / Mice / Animals / Male / Skin / Middle Aged / Anti-Bacterial Agents / Adult / Foot / Antimicrobial agents / Side Effect / Quinolines / Mycobacterium leprae / Fluoroquinolones / Bactericidal Activity

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Proarrhythmia as a Class Effect of Quinolones: Increased Dispersion of Repolarization and Triangulation of Action Potential Predict Torsades de Pointes

Electrocardiography / Animals / Male / Quinolones / Action potential / Ciprofloxacin / Rabbits / Quinolines / Ofloxacin / Action Potentials / Fluoroquinolones / Levofloxacin / Torsades de pointes / Torsade de Pointes / Ciprofloxacin / Rabbits / Quinolines / Ofloxacin / Action Potentials / Fluoroquinolones / Levofloxacin / Torsades de pointes / Torsade de Pointes

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