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Quinolines
Quinolines
Proarrhythmia as a Class Effect of Quinolones: Increased Dispersion of Repolarization and Triangulation of Action Potential Predict Torsades de Pointes
Electrocardiography / Animals / Male / Quinolones / Action potential / Ciprofloxacin / Rabbits / Quinolines / Ofloxacin / Action Potentials / Fluoroquinolones / Levofloxacin / Ciprofloxacin / Rabbits / Quinolines / Ofloxacin / Action Potentials / Fluoroquinolones / Levofloxacin
Biological evaluation of omega-(dialkylamino)alkyl derivatives of 6H-indolo[2,3-b]quinoline--novel cytotoxic DNA topoisomerase II inhibitors
DNA / Humans / Alkaloids / Anticancer / KB cells / Microbial Sensitivity Tests / Quinolines / Microbial Sensitivity Tests / Quinolines
Intracameral Moxifloxacin: In Vitro Safety on Human Ocular Cells
Cornea / Retinal Pigment Epithelium / Humans / Clinical Sciences / Eye / Optometry and Ophthalmology / Cell Proliferation / Quinolines / Trabecular Meshwork / Cell Survival / Fluoroquinolones / Optometry and Ophthalmology / Cell Proliferation / Quinolines / Trabecular Meshwork / Cell Survival / Fluoroquinolones
[Intracameral moxifloxacin: a safe option for endophthalmitis prophylaxis? In vitro safety profile for intraocular application]
Oxidative Stress / Endophthalmitis / Humans / Endothelial Cells / Clinical Sciences / Lipopolysaccharides / Optometry and Ophthalmology / Quinolines / Somatic Cell Count / Trabecular Meshwork / Cell Survival / Neurosciences / Fluoroquinolones / Lipopolysaccharides / Optometry and Ophthalmology / Quinolines / Somatic Cell Count / Trabecular Meshwork / Cell Survival / Neurosciences / Fluoroquinolones
Design, synthesis and melatoninergic potency of new N-acyl 8,9-dihydro-4-methoxy-7H-2-benzo[de]quinolinalkanamines
Organic Chemistry / Magnetic Resonance Spectroscopy / Melatonin / Bioorganic Chemistry / Humans / Mice / Animals / Drug Design / Xenopus laevis / Biotransformation / Quinolines / Melanophores / Binding Site / Bioorganic / Mice / Animals / Drug Design / Xenopus laevis / Biotransformation / Quinolines / Melanophores / Binding Site / Bioorganic
5-Benzylidene 1,2-Dihydrochromeno[3,4- f ]quinolines, A Novel Class of Nonsteroidal Human Progesterone Receptor Agonists
Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Progesterone / Humans / Female / Animals / Rats / Medicinal / Quinolines / Structure activity Relationship / Uterus / Ovariectomy / Female / Animals / Rats / Medicinal / Quinolines / Structure activity Relationship / Uterus / Ovariectomy
5-Aryl-1,2-dihydrochromeno[3,4- f ]quinolines: A Novel Class of Nonsteroidal Human Progesterone Receptor Agonists
Organic Chemistry / Medicinal Chemistry / Magnetic Resonance Spectroscopy / Humans / Female / Animals / Rats / Medicinal / Quinolines / Structure activity Relationship / Uterus / Animals / Rats / Medicinal / Quinolines / Structure activity Relationship / Uterus
Efficacy of Ciprofloxacin and Moxifloxacin against Nocardia brasiliensis In Vitro and in an Experimental Model of Actinomycetoma in BALB/c Mice
Microbiology / Medical Microbiology / Mice / Female / Animals / Antimicrobial agents / Microbial Sensitivity Tests / Mycetoma / Ciprofloxacin / Quinolines / Nocardia / Fluoroquinolones / Experimental Model / Antimicrobial agents / Microbial Sensitivity Tests / Mycetoma / Ciprofloxacin / Quinolines / Nocardia / Fluoroquinolones / Experimental Model
In vitro and in vivo comparison of two non-peptide tachykinin NK3 receptor antagonists: Improvements in efficacy achieved through enhanced brain penetration or altered pharmacological characteristics
Animal Behavior / Prefrontal Cortex / Nucleus Accumbens / Dopamine / Brain / Humans / Cerebral Cortex / Animals / Male / Central Nervous System / Peptides / Habenula / Neurons / Haloperidol / European / Microdialysis / Molecular cloning / Rats / Neuronal Activity / Guinea Pig / Substance P / Quinolines / Extracellular Space / Medial Prefrontal Cortex / Clinical evaluation / Humans / Cerebral Cortex / Animals / Male / Central Nervous System / Peptides / Habenula / Neurons / Haloperidol / European / Microdialysis / Molecular cloning / Rats / Neuronal Activity / Guinea Pig / Substance P / Quinolines / Extracellular Space / Medial Prefrontal Cortex / Clinical evaluation
Poly(ADP-Ribose) Polymerase Inhibition Alleviates Experimental Diabetic Sensory Neuropathy
Diabetes / Immunohistochemistry / Oxidative Stress / Apoptosis / Blood Glucose / Animals / Male / Neurons / Rats / Body Weight / Wistar Rats / Quinolines / Hyperalgesia / Tyrosine / Animals / Male / Neurons / Rats / Body Weight / Wistar Rats / Quinolines / Hyperalgesia / Tyrosine
Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison
Survival Analysis / Treatment Outcome / Adolescent / Myanmar / Humans / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk
Costo-Efectividad del Tratamiento de Salmeterol/Fluticasona en Comparación con Leucotrieno Montelukast para el Control del Asma Infantil
Asthma / Treatment Outcome / Adolescent / Applied Economics / Mexico / Prospective studies / Humans / Child / Hospitalization / Cost effectiveness / Public health systems and services research / Time Factors / Economic Models / Cost Benefit Analysis / Drug Costs / Cost Savings / MEXICO / Quinolines / Prospective studies / Humans / Child / Hospitalization / Cost effectiveness / Public health systems and services research / Time Factors / Economic Models / Cost Benefit Analysis / Drug Costs / Cost Savings / MEXICO / Quinolines
Antiplasmodial activity of Aspidosperma indole alkaloids
Complementary and Alternative Medicine / Plant Biology / Phytomedicine / Cell line / Humans / Animals / Drug Resistance / Alkaloids / Plant extracts / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinolines / Chloroquine / Structure activity Relationship / Indole Alkaloids / Molecular Structure / Animals / Drug Resistance / Alkaloids / Plant extracts / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinolines / Chloroquine / Structure activity Relationship / Indole Alkaloids / Molecular Structure
Phase transfer catalyzed synthesis of bis-quinolines: Antileishmanial activity in experimental visceral leishmaniasis and in vitro antibacterial evaluation
Organic Chemistry / Catalysis / Treatment / Transmission Electron Microscopy / In Vitro / Mice / Animals / Visceral Leishmaniasis / Methane / European / Antibacterial activity / In Vivo / Anti-Bacterial Agents / Microbial Sensitivity Tests / Quinolines / Structure activity Relationship / Chemical Synthesis / Mice / Animals / Visceral Leishmaniasis / Methane / European / Antibacterial activity / In Vivo / Anti-Bacterial Agents / Microbial Sensitivity Tests / Quinolines / Structure activity Relationship / Chemical Synthesis
Photosensitized DNA cleavage promoted by amino acidsElectronic Supplementary Information (ESI) available: procedures for TO?peptide syntheses and experimental details for photochemical experiments. See http://www.rsc.org/suppdata/cc/b3/b306008j/
Chemical / Fluorescent Dyes and Reagents / DNA / Escherichia coli / Plasmids / CHEMICAL SCIENCES / Amino Acids / Time Factors / Thiazoles / Quinolines / Molecular Structure / CHEMICAL SCIENCES / Amino Acids / Time Factors / Thiazoles / Quinolines / Molecular Structure
Comparative Ex Vivo Activity of Novel Endoperoxides in Multidrug-Resistant Plasmodium falciparum and P. vivax
Microbiology / Medical Microbiology / Plasmodium falciparum / Antimalarials / Microbial Sensitivity Tests / Quinolines / Chloroquine / Adamantane / Amodiaquine / Plasmodium Vivax / Quinolines / Chloroquine / Adamantane / Amodiaquine / Plasmodium Vivax
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