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Protozoan Proteins

Conservation and developmental control of alternative splicing in maebl among malaria parasites

Molecular Biology / Gene expression / Molecular / Humans / Sequence alignment / Animals / Alternative splicing / Life Cycle / Gene Structure / EBP / Plasmodium falciparum / Western blot / Alternative Splicing / Codon / Protein isoforms / Protozoan Proteins / Amino Acid Sequence / Base Sequence / Plasmodium yoelii / Protein Binding / Ligand / Plasmodium Vivax / Biochemistry and cell biology / Molecular Sequence Data / Animals / Alternative splicing / Life Cycle / Gene Structure / EBP / Plasmodium falciparum / Western blot / Alternative Splicing / Codon / Protein isoforms / Protozoan Proteins / Amino Acid Sequence / Base Sequence / Plasmodium yoelii / Protein Binding / Ligand / Plasmodium Vivax / Biochemistry and cell biology / Molecular Sequence Data

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Recombinant Plasmepsin 1 from the Human Malaria Parasite Plasmodium falciparum : Enzymatic Characterization, Active Site Inhibitor Design, and Structural Analysis

Biochemistry / Catalysis / Kinetics / Enzyme Inhibitors / Humans / Animals / Structure Analysis / Solubility / Active site / Substrate Specificity / Plasmodium falciparum / Protozoan Proteins / Amino Acid Sequence / Amino Acid Substitution Rates / Structure activity Relationship / Recombinant Proteins / Hydrogen-Ion Concentration / Biochemistry and cell biology / Molecular Structure / Molecular Sequence Data / Animals / Structure Analysis / Solubility / Active site / Substrate Specificity / Plasmodium falciparum / Protozoan Proteins / Amino Acid Sequence / Amino Acid Substitution Rates / Structure activity Relationship / Recombinant Proteins / Hydrogen-Ion Concentration / Biochemistry and cell biology / Molecular Structure / Molecular Sequence Data

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In Vitro Sensitivities of Plasmodium falciparum to Different Antimalarial Drugs in Uganda

Microbiology / Medical Microbiology / Uganda / Treatment Outcome / Humans / Child / Mutation / Drug Resistance / Membrane transport proteins / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Protozoan Proteins / Quinolines / Chloroquine / Cohort Studies / Child / Mutation / Drug Resistance / Membrane transport proteins / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Protozoan Proteins / Quinolines / Chloroquine / Cohort Studies

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Cutting Edge: A New Tool to Evaluate Human Pre-Erythrocytic Malaria Vaccines: Rodent Parasites Bearing a Hybrid Plasmodium falciparum Circumsporozoite Protein

Immunology / Immunology of the Gut / Humans / Mice / Anopheles / Animals / The / Plasmodium falciparum / Protozoan Proteins / Amino Acid Sequence / Erythrocytes / Malaria Vaccines / Salivary Glands / Molecular Sequence Data / Animals / The / Plasmodium falciparum / Protozoan Proteins / Amino Acid Sequence / Erythrocytes / Malaria Vaccines / Salivary Glands / Molecular Sequence Data

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New insights into parasite rhomboid proteases

Membrane Proteins / Mitochondria / Signal Transduction / Biological Sciences / Phylogeny / Animals / Rom / Signalling / TRAP / Replication / Phagocytosis / Substrate Specificity / TMD / Protozoan Proteins / RIP / Mitochondrial Proteins / Cell Membrane / Animals / Rom / Signalling / TRAP / Replication / Phagocytosis / Substrate Specificity / TMD / Protozoan Proteins / RIP / Mitochondrial Proteins / Cell Membrane

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Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression

Cell Cycle / Gene expression / Multidisciplinary / Drug Resistance / Membrane transport proteins / PLoS one / Plasmodium falciparum / Antimalarials / Combination drug therapy / Protozoan Proteins / Erythrocytes / Non linear regression / Mefloquine / Gene Expression Regulation / PLoS one / Plasmodium falciparum / Antimalarials / Combination drug therapy / Protozoan Proteins / Erythrocytes / Non linear regression / Mefloquine / Gene Expression Regulation

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Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase

Physiology / Membrane Proteins / Enzyme Inhibitors / Humans / Animals / Cell Death / Hepatitis C Virus / Medical Physiology / Molecular cloning / Active site / Plasmodium falciparum / Protozoan Proteins / MHC class I / Biochemistry and cell biology / Proteolytic activity / Cell Death / Hepatitis C Virus / Medical Physiology / Molecular cloning / Active site / Plasmodium falciparum / Protozoan Proteins / MHC class I / Biochemistry and cell biology / Proteolytic activity

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Predominant clonal evolution leads to a close parity between gene expression profiles and subspecific phylogeny in Trypanosoma cruzi

Polymorphism / Molecular Evolution / Horizontal Gene Transfer / Gene expression / Natural Selection / Biological Sciences / Phylogeny / Animals / DNA fingerprinting / Chagas disease / Phylogenetic Diversity / Electrophoresis / Trypanosoma Cruzi / Genetic Recombination / Genetic variation / Protozoan Proteins / Gene expression profiling / DNA sequence / Differential expression / Biological Sciences / Phylogeny / Animals / DNA fingerprinting / Chagas disease / Phylogenetic Diversity / Electrophoresis / Trypanosoma Cruzi / Genetic Recombination / Genetic variation / Protozoan Proteins / Gene expression profiling / DNA sequence / Differential expression

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A transcriptional switch underlies commitment to sexual development in malaria parasites

Biology / Malaria / Medicine / Multidisciplinary / Gene Silencing / Nature / Germ Cells / Female / Animals / Parasites / Male / Plasmodium falciparum / Sex Differentiation / Sexual Development / Protozoan Proteins / DNA binding proteins / Gene Expression Regulation / Nature / Germ Cells / Female / Animals / Parasites / Male / Plasmodium falciparum / Sex Differentiation / Sexual Development / Protozoan Proteins / DNA binding proteins / Gene Expression Regulation

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Plasmodium falciparum TryThrA antigen synthetic peptides block in vitro merozoite invasion to erythrocytes

Membrane Proteins / Biophysical Chemistry / Humans / Animals / Peptides / Goats / Plasmodium falciparum / Protozoan Proteins / Erythrocytes / Biochemistry and cell biology / Merozoite surface protein 1 / Goats / Plasmodium falciparum / Protozoan Proteins / Erythrocytes / Biochemistry and cell biology / Merozoite surface protein 1

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Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

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Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

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From genomes to vaccines: Leishmania as a model

Leishmania / Biological Sciences / Humans / Animals / DNA vaccines / Protozoan Proteins / Proteome / Gene expression profiling / Protozoan Proteins / Proteome / Gene expression profiling

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Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif

Molecular Microbiology / Biological Sciences / Molecular / Animals / Endoplasmic Reticulum / Plasmodium falciparum / Protozoan Proteins / Protein Binding / Protein Transport / Plasmodium falciparum / Protozoan Proteins / Protein Binding / Protein Transport

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LeishCyc: a biochemical pathways database for Leishmania major

Data Mining / Metabolomics / Proteomics / Humans / System Analysis / Animals / Error Correction / Genome Annotation / Spectrum / Digestive Tract / Plasmodium falciparum / Yeast Metabolite Profiling / Genome sequence / Protozoan Proteins / Metabolic pathway / Literature Search / Drug Targeting / Leishmania Major / Web Interface / Animals / Error Correction / Genome Annotation / Spectrum / Digestive Tract / Plasmodium falciparum / Yeast Metabolite Profiling / Genome sequence / Protozoan Proteins / Metabolic pathway / Literature Search / Drug Targeting / Leishmania Major / Web Interface

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LeishCyc: a biochemical pathways database for Leishmania major

Data Mining / Metabolomics / Proteomics / Humans / System Analysis / Animals / Error Correction / Genome Annotation / Spectrum / Digestive Tract / Plasmodium falciparum / Yeast Metabolite Profiling / Genome sequence / Protozoan Proteins / Metabolic pathway / Literature Search / Drug Targeting / Leishmania Major / Web Interface / Animals / Error Correction / Genome Annotation / Spectrum / Digestive Tract / Plasmodium falciparum / Yeast Metabolite Profiling / Genome sequence / Protozoan Proteins / Metabolic pathway / Literature Search / Drug Targeting / Leishmania Major / Web Interface

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