PLoS one

Intense Synaptic Activity Enhances Temporal Resolution in Spinal Motoneurons

Electrophysiology / Temporal Resolution / Multidisciplinary / Stochastic processes / Computer Simulation / Animals / Spinal Cord / Turtles / Neurons / PLoS one / Motor System / Time Factors / SYNAPSES / Action potential / Membrane Potential / Action Potentials / Electric Conductivity / Motor activity / Animals / Spinal Cord / Turtles / Neurons / PLoS one / Motor System / Time Factors / SYNAPSES / Action potential / Membrane Potential / Action Potentials / Electric Conductivity / Motor activity

Impaired Proteostasis Contributes to Renal Tubular Dysgenesis

Engineering / Physics / Chemistry / Biology / Medicine / Multidisciplinary / Pregnancy / Humans / Female / Male / Endoplasmic Reticulum / Infant / PLoS one / Enzyme / Newborn Infant / Homeostasis / Protein Conformation / Angiotensin Converting Enzyme / Base Sequence / Cell Surface Markers / Plasma Membrane / Protein Transport / Multidisciplinary / Pregnancy / Humans / Female / Male / Endoplasmic Reticulum / Infant / PLoS one / Enzyme / Newborn Infant / Homeostasis / Protein Conformation / Angiotensin Converting Enzyme / Base Sequence / Cell Surface Markers / Plasma Membrane / Protein Transport

New Antimalarial Hits from Dacryodes edulis (Burseraceae) - Part I: Isolation, In Vitro Activity, In Silico “drug-likeness� and Pharmacokinetic Profiles

Drug interactions / Multidisciplinary / Cell line / Animals / PLoS one / Plant extracts / Epithelial cells / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinine / Plant extracts / Epithelial cells / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinine

HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model

Enzyme Inhibitors / Gene expression / Multidisciplinary / Cerebellum / Mice / Animals / Histone Modification / PLoS one / Chromatin / Introns / Histones / Mouse Model / Microarray Analysis / Myocardium / Chromatin Immunoprecipitation / Western blot / Acetylation / Neurodegenerative Disease / Histone deacetylase inhibitor / Nervous System / Autosomal Recessive / Acute Toxicity / Cardiac Disease / Friedreich Ataxia / Gene expression profiling / Histone deacetylase inhibitors / Iron binding proteins / Animals / Histone Modification / PLoS one / Chromatin / Introns / Histones / Mouse Model / Microarray Analysis / Myocardium / Chromatin Immunoprecipitation / Western blot / Acetylation / Neurodegenerative Disease / Histone deacetylase inhibitor / Nervous System / Autosomal Recessive / Acute Toxicity / Cardiac Disease / Friedreich Ataxia / Gene expression profiling / Histone deacetylase inhibitors / Iron binding proteins

Determination of Variation Parameters as a Crucial Step in Designing TMT-Based Clinical Proteomics Experiments

Proteomics / Multidisciplinary / Humans / Female / Male / Cluster Analysis / Peptides / Tandem Mass Spectrometry / PLoS one / Middle Aged / Pilot Projects / Proteome / Cluster Analysis / Peptides / Tandem Mass Spectrometry / PLoS one / Middle Aged / Pilot Projects / Proteome

Characterization of Membrane Potential Dependency of Mitochondrial Ca2+ Uptake by an Improved Biophysical Model of Mitochondrial Ca2+ Uniporter

Biophysics / Calcium / Mitochondria / Multidisciplinary / Humans / Mice / Animals / Calcium channels / Organophosphorus Compounds / Non small cell carcinoma / PLoS one / Clinical Sciences / Theoretical Models / Mice / Animals / Calcium channels / Organophosphorus Compounds / Non small cell carcinoma / PLoS one / Clinical Sciences / Theoretical Models

Residual endotoxin contaminations in recombinant proteins are sufficient to activate human CD1c+ dendritic cells

Multidisciplinary / Dendritic Cells / Humans / Escherichia coli / Glycoproteins / PLoS one / Lipopolysaccharides / Recombinant Proteins / Endotoxins / PLoS one / Lipopolysaccharides / Recombinant Proteins / Endotoxins

New mitochondrial and nuclear evidences support recent demographic expansion and an atypical phylogeographic pattern in the spittlebug Philaenus spumarius (Hemiptera, Aphrophoridae)

Demography / Phylogeography / Mitochondria / Multidisciplinary / Phylogeny / Mitochondrial DNA / Humans / Haplotypes / Animals / Population Growth / Hemiptera / PLoS one / Cell nucleus / Time Factors / Genetic variation / Likelihood Functions / Mitochondrial DNA / Humans / Haplotypes / Animals / Population Growth / Hemiptera / PLoS one / Cell nucleus / Time Factors / Genetic variation / Likelihood Functions

Perinatal Maternal Administration of Lactobacillus paracasei NCC 2461 Prevents Allergic Inflammation in a Mouse Model of Birch Pollen Allergy

Immune response / Probiotics / Lactation / Multidisciplinary / Cell Culture / Toll like receptor signaling / Pregnancy / Pollen / Mice / Female / Animals / Lactobacillus / Drinking Water / Immunoglobulin E / Lung / PLoS one / mRna expression levels / Mouse Model / Betula / Mechanism of action / Cell Proliferation / Maternal-fetal exchange / immunoglobulin G / Bronchoalveolar lavage / Airway Inflammation / Toll like receptor signaling / Pregnancy / Pollen / Mice / Female / Animals / Lactobacillus / Drinking Water / Immunoglobulin E / Lung / PLoS one / mRna expression levels / Mouse Model / Betula / Mechanism of action / Cell Proliferation / Maternal-fetal exchange / immunoglobulin G / Bronchoalveolar lavage / Airway Inflammation

No sustained attention differences in a longitudinal randomized trial comparing mindfulness based stress reduction versus active control

Health Promotion / Mindfulness / Attention / Multidisciplinary / Humans / Female / Male / Young Adult / PLoS one / Middle Aged / Arousal / Longitudinal Studies / Adult / Time Factors / Female / Male / Young Adult / PLoS one / Middle Aged / Arousal / Longitudinal Studies / Adult / Time Factors

Anodal Transcranial Direct Current Stimulation Enhances Procedural Consolidation

Engineering / Psychology / Cognitive Science / Music / Transcranial Magnetic Stimulation / Treatment Outcome / Cognitive Neuroscience / Neurophysiology / Multidisciplinary / Pain Management / Memory / Visual Cortex / Humans / Hemodynamics / Cerebral Cortex / Chronic Disease / Female / Male / Cortex / Young Adult / Analgesia / Cerebellar ataxia / Motor Cortex / PLoS one / Aged / Middle Aged / Brain Stimulation / Functional Neurology / Adult / Analysis of Variance / Sympathetic Nervous System / Upper Extremity / Electrodes / Cross-Over Studies / Neurosciences / Pain Measurement / Pain Threshold / Acoustic Stimulation / Psychomotor Performance / Treatment Outcome / Cognitive Neuroscience / Neurophysiology / Multidisciplinary / Pain Management / Memory / Visual Cortex / Humans / Hemodynamics / Cerebral Cortex / Chronic Disease / Female / Male / Cortex / Young Adult / Analgesia / Cerebellar ataxia / Motor Cortex / PLoS one / Aged / Middle Aged / Brain Stimulation / Functional Neurology / Adult / Analysis of Variance / Sympathetic Nervous System / Upper Extremity / Electrodes / Cross-Over Studies / Neurosciences / Pain Measurement / Pain Threshold / Acoustic Stimulation / Psychomotor Performance

Role of Proton Pump Inhibitor on Esophageal Carcinogenesis and Pancreatic Acinar Cell Metaplasia Development: An Experimental In Vivo Study

Multidisciplinary / Pancreas / Animals / Male / PLoS one / Rats / Proton Pump Inhibitors / Rats / Proton Pump Inhibitors

Combinatorial Engineering of Dextransucrase Specificity

Catalysis / Magnetic Resonance Spectroscopy / Multidisciplinary / Protein Engineering / Mutation / Glucans / PLoS one / Substrate Specificity / Glycosyltransferases / Amino Acid Sequence / Structure activity Relationship / Site-directed Mutagenesis / Leuconostoc / Glucans / PLoS one / Substrate Specificity / Glycosyltransferases / Amino Acid Sequence / Structure activity Relationship / Site-directed Mutagenesis / Leuconostoc

Egr-1 Activation by Cancer-Derived Extracellular Vesicles Promotes Endothelial Cell Migration via ERK1/2 and JNK Signaling Pathways

Multidisciplinary / RNA interference / Humans / Endothelial Cells / Mice / Animals / PLoS one / Neoplasms / Extracellular Vesicles / Animals / PLoS one / Neoplasms / Extracellular Vesicles
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