PLoS one

Periadventitial Application of Rapamycin-Loaded Nanoparticles Produces Sustained Inhibition of Vascular Restenosis

Nanoparticles / Multidisciplinary / Animals / Male / Drug Delivery Systems / Phosphorylation / Hyperplasia / PLoS one / Rats / Cell Proliferation / Sirolimus / Cell Survival / Phosphorylation / Hyperplasia / PLoS one / Rats / Cell Proliferation / Sirolimus / Cell Survival

Aspartoacylase-LacZ Knockin Mice: An Engineered Model of Canavan Disease

Multidisciplinary / Corpus Callosum / Optic Nerve / Mutation / Mice / Female / Animals / Male / Astrocyte / PLoS one / Enzyme / White matter / Degeneration / Schwann Cell / Myo-inositol / Canavan Disease / Female / Animals / Male / Astrocyte / PLoS one / Enzyme / White matter / Degeneration / Schwann Cell / Myo-inositol / Canavan Disease

MicroRNA Expression Characterizes Oligometastasis(es)

Multidisciplinary / Humans / Mice / Female / Animals / Cluster Analysis / Lung / PLoS one / microRNAs / Reproducibility of Results / Disease Progression / Gene expression profiling / Cluster Analysis / Lung / PLoS one / microRNAs / Reproducibility of Results / Disease Progression / Gene expression profiling

Catechol-O-Methyltransferase Expression and 2-Methoxyestradiol Affect Microtubule Dynamics and Modify Steroid Receptor Signaling in Leiomyoma Cells

Apoptosis / Multidisciplinary / Molecular Mechanics / Signal Transduction / Estrogen Receptor / Humans / Female / Microtubules / PLoS one / Subcellular Localization / Tumor necrosis factor-alpha / Cell Proliferation / Estradiol / Leiomyoma / Estrogen receptor alpha / Humans / Female / Microtubules / PLoS one / Subcellular Localization / Tumor necrosis factor-alpha / Cell Proliferation / Estradiol / Leiomyoma / Estrogen receptor alpha

Deep RNA Sequencing Reveals Hidden Features and Dynamics of Early Gene Transcription in Paramecium bursaria Chlorella Virus 1

Polyadenylation / Multidisciplinary / Transcriptome / Gene Dosage / PLoS one / Chlorella / Time Factors / Host Pathogen Interactions / Gene expression profiling / Chlorella / Time Factors / Host Pathogen Interactions / Gene expression profiling

Ancient DNA Suggests Dwarf and ‘Giant’ Emu Are Conspecific

Geography / Multidisciplinary / DNA / Phylogeny / Brain / Sequence alignment / Haplotypes / Fossils / Animals / Ancient DNA / Tasmania / Body Size / PLoS one / Time Factors / Species Specificity / Base Sequence / Sequence alignment / Haplotypes / Fossils / Animals / Ancient DNA / Tasmania / Body Size / PLoS one / Time Factors / Species Specificity / Base Sequence

Evaluation of an Antimicrobial L-Amino Acid Oxidase and Peptide Derivatives from Bothropoides mattogrosensis Pitviper Venom

Multidisciplinary / Humans / Bacterial resistance / Gram Positive / Animals / Viperidae / Antimicrobial activity / PLoS one / Enzyme / Gram Positive Bacteria / Antibacterial activity / Gram-negative bacteria / Antimicrobial Cationic Peptides / Cytotoxic Activity / Microbial Sensitivity Tests / Amino Acid Profile / Protein Conformation / Amino Acid Sequence / Theoretical Model / Static Electricity / Viperidae / Antimicrobial activity / PLoS one / Enzyme / Gram Positive Bacteria / Antibacterial activity / Gram-negative bacteria / Antimicrobial Cationic Peptides / Cytotoxic Activity / Microbial Sensitivity Tests / Amino Acid Profile / Protein Conformation / Amino Acid Sequence / Theoretical Model / Static Electricity

Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression

Cell Cycle / Gene expression / Multidisciplinary / Drug Resistance / Membrane transport proteins / PLoS one / Plasmodium falciparum / Antimalarials / Combination drug therapy / Protozoan Proteins / Erythrocytes / Non linear regression / Mefloquine / Gene Expression Regulation / PLoS one / Plasmodium falciparum / Antimalarials / Combination drug therapy / Protozoan Proteins / Erythrocytes / Non linear regression / Mefloquine / Gene Expression Regulation

Nuclear Legumain Activity in Colorectal Cancer

Engineering / Physics / Chemistry / Biology / Immunohistochemistry / Confocal Microscopy / Medicine / Multidisciplinary / RNA interference / Humans / Mutation / Mice / Female / Animals / PLoS one / Cell nucleus / Peer reviewed / Cysteine endopeptidases / Amino Acid Sequence / Lysosomes / Immunoblotting / Confocal Microscopy / Medicine / Multidisciplinary / RNA interference / Humans / Mutation / Mice / Female / Animals / PLoS one / Cell nucleus / Peer reviewed / Cysteine endopeptidases / Amino Acid Sequence / Lysosomes / Immunoblotting

Species Identification and Profiling of Complex Microbial Communities Using Shotgun Illumina Sequencing of 16S rRNA Amplicon Sequences

Computational Biology / Multidisciplinary / Phylogeny / Humans / Bacteria / PLoS one / Adult / Gastrointestinal Tract / Metagenome / PLoS one / Adult / Gastrointestinal Tract / Metagenome

Periadventitial Application of Rapamycin-Loaded Nanoparticles Produces Sustained Inhibition of Vascular Restenosis

Nanoparticles / Multidisciplinary / Animals / Male / Drug Delivery Systems / Phosphorylation / Hyperplasia / PLoS one / Rats / Cell Proliferation / Sirolimus / Cell Survival / Phosphorylation / Hyperplasia / PLoS one / Rats / Cell Proliferation / Sirolimus / Cell Survival

Protein-Losing Enteropathy in Systemic Lupus erythematosus

Treatment Outcome / Adolescent / Multidisciplinary / Biopsy / Humans / Child / Systemic Lupus Erythematosus / Intestinal Mucosa / Cholesterol / Female / Digestion / Male / Prednisolone / Jejunum / Risk factors / Diagnostic Imaging / PLoS one / Colonoscopy / Clinical Sciences / Aged / Middle Aged / Neutrophils / Adult / Edema / Feces / Retrospective Studies / Tumor necrosis factor-alpha / Prognosis / Risk Factors / Human Pathology / Proteinuria / Lupus / Cyclophosphamide / Ascites / Glucocorticoids / Synovial-fluid / Glomerulonephritis / Alpha-1 Antitrypsin / Nephrotic syndrome / Case Control Studies / Autoantigens / Interleukin / Duodenum / Serum albumin / Child / Systemic Lupus Erythematosus / Intestinal Mucosa / Cholesterol / Female / Digestion / Male / Prednisolone / Jejunum / Risk factors / Diagnostic Imaging / PLoS one / Colonoscopy / Clinical Sciences / Aged / Middle Aged / Neutrophils / Adult / Edema / Feces / Retrospective Studies / Tumor necrosis factor-alpha / Prognosis / Risk Factors / Human Pathology / Proteinuria / Lupus / Cyclophosphamide / Ascites / Glucocorticoids / Synovial-fluid / Glomerulonephritis / Alpha-1 Antitrypsin / Nephrotic syndrome / Case Control Studies / Autoantigens / Interleukin / Duodenum / Serum albumin

A Novel Artificial MicroRNA Expressing AAV Vector for Phospholamban Silencing in Cardiomyocytes Improves Ca2+ Uptake into the Sarcoplasmic Reticulum

Inflammation / Calcium / Proteomics / Multidisciplinary / Gene Silencing / Western blotting / Humans / Animals / PLoS one / microRNAs / Myocardium / Reproducibility of Results / Wistar Rats / Calcium Binding Proteins / Sarcoplasmic reticulum / Western blotting / Humans / Animals / PLoS one / microRNAs / Myocardium / Reproducibility of Results / Wistar Rats / Calcium Binding Proteins / Sarcoplasmic reticulum

Brazilian Road Traffic Fatalities: A Spatial and Environmental Analysis

Brazil / Public Health / Multidisciplinary / Safety / Humans / Risk factors / PLoS one / Risk Factors / Environment / Risk factors / PLoS one / Risk Factors / Environment
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