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Nucleosides
Nucleosides
Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H + cotransporter (NupC) produced in Xenopus laevis oocytes
Kinetics / Molecular / Humans / Sequence alignment / Escherichia coli / Female / Animals / Membrane transport proteins / Protein Sequence Analysis / Substrate Specificity / Xenopus laevis / Oocytes / Nucleosides / Recombinant Proteins / Antineoplastic Agents / Antiviral Agents / Biochemistry and cell biology / Molecular Sequence Data / Female / Animals / Membrane transport proteins / Protein Sequence Analysis / Substrate Specificity / Xenopus laevis / Oocytes / Nucleosides / Recombinant Proteins / Antineoplastic Agents / Antiviral Agents / Biochemistry and cell biology / Molecular Sequence Data
Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H + cotransporter (NupC) produced in Xenopus laevis oocytes
Kinetics / Molecular / Humans / Sequence alignment / Escherichia coli / Female / Animals / Membrane transport proteins / Protein Sequence Analysis / Substrate Specificity / Xenopus laevis / Oocytes / Nucleosides / Recombinant Proteins / Antineoplastic Agents / Antiviral Agents / Biochemistry and cell biology / Female / Animals / Membrane transport proteins / Protein Sequence Analysis / Substrate Specificity / Xenopus laevis / Oocytes / Nucleosides / Recombinant Proteins / Antineoplastic Agents / Antiviral Agents / Biochemistry and cell biology
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy
Kinetics / Biological Sciences / Phylogeny / Xenopus / Animals / Biochemical / CHEMICAL SCIENCES / Molecular cloning / Protein Secondary Structure Prediction / Time Factors / Substrate Specificity / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Nucleosides / Cations / Hydrogen-Ion Concentration / Adenine / Biochemical / CHEMICAL SCIENCES / Molecular cloning / Protein Secondary Structure Prediction / Time Factors / Substrate Specificity / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Nucleosides / Cations / Hydrogen-Ion Concentration / Adenine
A sensitive LC–MS/MS method for quantification of a nucleoside analog in plasma: Application to in vivo rat pharmacokinetic studies
Analytical Chemistry / Mass Spectrometry / Quality Control / Quantitative analysis / Humans / Stable Isotope / Animals / Tandem Mass Spectrometry / Anti-inflammatory agents / High Performance Liquid Chromatography / High Pressure Liquid Chromatography / Rats / Reproducibility of Results / Wistar Rats / Quantitative Analysis / Acetic Acid / Sensitivity and Specificity / Nucleosides / Freezing / Antiviral Agents / Biochemistry and cell biology / Mass Spectrometer / Stable Isotope / Animals / Tandem Mass Spectrometry / Anti-inflammatory agents / High Performance Liquid Chromatography / High Pressure Liquid Chromatography / Rats / Reproducibility of Results / Wistar Rats / Quantitative Analysis / Acetic Acid / Sensitivity and Specificity / Nucleosides / Freezing / Antiviral Agents / Biochemistry and cell biology / Mass Spectrometer
Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity
Kinetics / Enzyme Inhibitors / Gene expression / Manganese / Biological Sciences / Humans / Magnesium / Mathematical Sciences / Nucleic Acids / Proteins / HeLa cells / Substrate Specificity / Sensitivity and Specificity / Nucleosides / Recombinant Proteins / Hydrolysis / Humans / Magnesium / Mathematical Sciences / Nucleic Acids / Proteins / HeLa cells / Substrate Specificity / Sensitivity and Specificity / Nucleosides / Recombinant Proteins / Hydrolysis
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy
Kinetics / Biological Sciences / Phylogeny / Xenopus / Animals / Biochemical / CHEMICAL SCIENCES / Molecular cloning / Protein Secondary Structure Prediction / Time Factors / Substrate Specificity / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Nucleosides / Cations / Hydrogen-Ion Concentration / Adenine / Biochemical / CHEMICAL SCIENCES / Molecular cloning / Protein Secondary Structure Prediction / Time Factors / Substrate Specificity / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Nucleosides / Cations / Hydrogen-Ion Concentration / Adenine
Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H + cotransporter (NupC) produced in Xenopus laevis oocytes
Kinetics / Molecular / Humans / Sequence alignment / Escherichia coli / Female / Animals / Membrane transport proteins / Protein Sequence Analysis / Substrate Specificity / Xenopus laevis / Oocytes / Nucleosides / Recombinant Proteins / Antineoplastic Agents / Antiviral Agents / Biochemistry and cell biology / Female / Animals / Membrane transport proteins / Protein Sequence Analysis / Substrate Specificity / Xenopus laevis / Oocytes / Nucleosides / Recombinant Proteins / Antineoplastic Agents / Antiviral Agents / Biochemistry and cell biology
Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein
Membrane Proteins / Biological Chemistry / Gene expression / Biological Sciences / Xenopus / Humans / Animals / Biological / CHEMICAL SCIENCES / Molecular cloning / Rats / Rat / Protein Conformation / Amino Acid Sequence / Base Sequence / Oocytes / Nucleosides / Humans / Animals / Biological / CHEMICAL SCIENCES / Molecular cloning / Rats / Rat / Protein Conformation / Amino Acid Sequence / Base Sequence / Oocytes / Nucleosides
Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines
Flow Cytometry / Cell Division / Signal Transduction / DNA / Cell line / Adenosine / Neuro-Oncology / Humans / Glioma / Neuro / Nucleosides / Neurosciences / Extracellular Space / Brain Neoplasms / Nucleotides / Adenosine Triphosphate / Adenosine Diphosphate / Adenosine / Neuro-Oncology / Humans / Glioma / Neuro / Nucleosides / Neurosciences / Extracellular Space / Brain Neoplasms / Nucleotides / Adenosine Triphosphate / Adenosine Diphosphate
Amino acid phosphoramidate nucleosides: potential ADEPT/GDEPT substrates
Organic Chemistry / Leukemia / Cell Division / Enzymes / Cell line / Humans / Amides / Substrate Specificity / Amino Acid Profile / Water soluble polymers / Nucleosides / Protein Tyrosine Phosphatases / Humans / Amides / Substrate Specificity / Amino Acid Profile / Water soluble polymers / Nucleosides / Protein Tyrosine Phosphatases
Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity
Kinetics / Enzyme Inhibitors / Gene expression / Manganese / Biological Sciences / Humans / Magnesium / ATPase / Mathematical Sciences / Nucleic Acids / Proteins / RNA Helicase A / HeLa cells / Substrate Specificity / Sensitivity and Specificity / Nucleosides / Recombinant Proteins / Hydrolysis / Humans / Magnesium / ATPase / Mathematical Sciences / Nucleic Acids / Proteins / RNA Helicase A / HeLa cells / Substrate Specificity / Sensitivity and Specificity / Nucleosides / Recombinant Proteins / Hydrolysis
Competitive Inhibition of Human Poly(A)-Specific Ribonuclease (PARN) by Synthetic Fluoro-Pyranosyl Nucleosides
Biochemistry / Kinetics / Enzyme Inhibitors / Biocatalysis / Humans / Computer Simulation / Magnesium / Glucose / Hydrogen Bonding / Nucleosides / Recombinant Proteins / Biochemistry and cell biology / Computer Simulation / Magnesium / Glucose / Hydrogen Bonding / Nucleosides / Recombinant Proteins / Biochemistry and cell biology
Efficient synthesis of exomethylene- and keto-exomethylene-d-glucopyranosyl nucleoside analogs as potential cytotoxic agents
Organic Chemistry / Humans / Mice / Animals / Cell Proliferation / Nucleosides / Antineoplastic Agents / Carbohydrate / Cytotoxins / Biochemistry and cell biology / Nucleosides / Antineoplastic Agents / Carbohydrate / Cytotoxins / Biochemistry and cell biology
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