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Mutagenesis
Mutagenesis
Acacia salicina extracts protect against DNA damage and mutagenesis in bacteria and human lymphoblast cell K562 cultures
Nutrition and Dietetics / Nutrition / DNA damage / Antioxidants / Humans / Mutagenesis / Salmonella Typhimurium / Acacia / Hydrogen Peroxide / Comet Assay / Ames Test / Integrated Approach / Antioxidant Activity / Ethyl Acetate / Plant extracts / Superoxide Anion / Xanthine Oxidase / Plant Leaves / Mutagenesis / Salmonella Typhimurium / Acacia / Hydrogen Peroxide / Comet Assay / Ames Test / Integrated Approach / Antioxidant Activity / Ethyl Acetate / Plant extracts / Superoxide Anion / Xanthine Oxidase / Plant Leaves
A biotechnological method provides access to aggregation competent monomeric Alzheimer\'s 1-42 residue amyloid peptide
Physical Chemistry / Electron Microscopy / Mass Spectrometry / Gene expression / Multidisciplinary / Protein Engineering / Humans / Mutagenesis / Escherichia coli / Bio Technology / Animals / High Pressure Liquid Chromatography / Solutions / Plasmodium falciparum / Amino Acid Sequence / Protein Engineering / Humans / Mutagenesis / Escherichia coli / Bio Technology / Animals / High Pressure Liquid Chromatography / Solutions / Plasmodium falciparum / Amino Acid Sequence
loco encodes an RGS protein required for Drosophila glial differentiation
Transcription Factors / Development / Gene expression / Biological Sciences / Drosophila / Cell Differentiation / Humans / Mutagenesis / Animals / Peripheral Nervous System / Central Nervous System / Proteins / Phenotype / Rats / Amino Acid Sequence / Base Sequence / DNA binding proteins / Gtp Binding Proteins / Cell Differentiation / Humans / Mutagenesis / Animals / Peripheral Nervous System / Central Nervous System / Proteins / Phenotype / Rats / Amino Acid Sequence / Base Sequence / DNA binding proteins / Gtp Binding Proteins
Acacia salicina extracts protect against DNA damage and mutagenesis in bacteria and human lymphoblast cell K562 cultures
Nutrition and Dietetics / Nutrition / DNA damage / Antioxidants / Humans / Mutagenesis / Salmonella Typhimurium / Acacia / Hydrogen Peroxide / Comet Assay / Ames Test / Integrated Approach / Antioxidant Activity / Ethyl Acetate / Plant extracts / Superoxide Anion / Xanthine Oxidase / Plant Leaves / Mutagenesis / Salmonella Typhimurium / Acacia / Hydrogen Peroxide / Comet Assay / Ames Test / Integrated Approach / Antioxidant Activity / Ethyl Acetate / Plant extracts / Superoxide Anion / Xanthine Oxidase / Plant Leaves
Resveratrol acts as a natural profungicide and induces self-intoxication by a specific laccase
Functional Analysis / Molecular Microbiology / Molecular Genetics / Gene expression / Plant Secondary metabolite / Biological Sciences / Molecular / Virulence / Prodrugs / Mutagenesis / Botrytis / Oxidoreductases / Laccase / Secondary Metabolites / Plant Pathogen interaction / Phenols / Botrytis cinerea / Stilbenes / Antifungal Agents / Vitis / Amino Acid Sequence / Base Sequence / Arachis Hypogaea / Host Plant / Plant Leaves / Biological Sciences / Molecular / Virulence / Prodrugs / Mutagenesis / Botrytis / Oxidoreductases / Laccase / Secondary Metabolites / Plant Pathogen interaction / Phenols / Botrytis cinerea / Stilbenes / Antifungal Agents / Vitis / Amino Acid Sequence / Base Sequence / Arachis Hypogaea / Host Plant / Plant Leaves
Molecular evolution by staggered extension process (StEP) in vitro recombination
Molecular Evolution / Multidisciplinary / Protein Engineering / Nature / Mutagenesis / Mutation / Polymerase Chain Reaction / Bacillus subtilis / Genetic Recombination / Recombinant Proteins / Mutation / Polymerase Chain Reaction / Bacillus subtilis / Genetic Recombination / Recombinant Proteins
Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer
Genetics / Oxidative Stress / DNA damage / Colorectal cancer / Mitochondrial DNA / Humans / Mutagenesis / Glucose / Glucose Metabolism / Reactive Oxygen Species / Female / Male / Glycolysis / Mitochondrial Genome / Aged / Middle Aged / Oxidative Damage / Oxidative phosphorylation / Experimental Tests / Genomic instability / PLoS Genetics / Humans / Mutagenesis / Glucose / Glucose Metabolism / Reactive Oxygen Species / Female / Male / Glycolysis / Mitochondrial Genome / Aged / Middle Aged / Oxidative Damage / Oxidative phosphorylation / Experimental Tests / Genomic instability / PLoS Genetics
Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors
Genetics / Caenorhabditis elegans / Enzyme Inhibitors / Apoptosis / Gene expression / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences
Biomonitoring human exposure to environmental carcinogenic chemicals
Petroleum / Environmental Monitoring / DNA damage / Humans / Mutagenesis / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies
Ca2+-dependent PKC activation mediates menthol-induced desensitization of transient receptor potential M8
Psychology / Cognitive Science / Calcium / Drug interactions / Enzyme Inhibitors / Patch-clamp and imaging techniques / Cell line / Humans / Mutagenesis / Transient receptor potential channels / Animals / Rats / Time Factors / Transfection / Neurosciences / Fura / Menthol / Patch-clamp and imaging techniques / Cell line / Humans / Mutagenesis / Transient receptor potential channels / Animals / Rats / Time Factors / Transfection / Neurosciences / Fura / Menthol
Development of an Efficient In Vivo System (Pjunc-TpaseIS1223) for Random Transposon Mutagenesis of Lactobacillus casei
Multidisciplinary / Mutagenesis / Escherichia coli / Electroporation / Applied Environmental Microbiology / Plasmids / Lactobacillus Casei / Plasmids / Lactobacillus Casei
Fidelity Variants of RNA Dependent RNA Polymerases Uncover an Indirect, Mutagenic Activity of Amiloride Compounds
Microbiology / Immunology / RNA / Medical Microbiology / Cercopithecus aethiops / Humans / Mutagenesis / Animals / HeLa cells / Genetic variation / Base Sequence / RNA Dependent RNA Polymerase / Mutagens / Vero cells / Antiviral Agents / Enterovirus / Humans / Mutagenesis / Animals / HeLa cells / Genetic variation / Base Sequence / RNA Dependent RNA Polymerase / Mutagens / Vero cells / Antiviral Agents / Enterovirus
Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systems
DNA repair / Gene expression / Biological Sciences / Cell line / Environmental Sciences / Mutagenesis / Mutation / Mice / Animals / Polymerase Chain Reaction / T cells / Nucleic Acids / Genetic Recombination / Transfection / Base Sequence / DNA binding proteins / Gene Transfer / Mutagenesis / Mutation / Mice / Animals / Polymerase Chain Reaction / T cells / Nucleic Acids / Genetic Recombination / Transfection / Base Sequence / DNA binding proteins / Gene Transfer
Resveratrol acts as a natural profungicide and induces self-intoxication by a specific laccase
Functional Analysis / Molecular Microbiology / Molecular Genetics / Gene expression / Plant Secondary metabolite / Biological Sciences / Molecular / Virulence / Prodrugs / Mutagenesis / Botrytis / Oxidoreductases / Laccase / Secondary Metabolites / Plant Pathogen interaction / Phenols / Botrytis cinerea / Stilbenes / Antifungal Agents / Vitis / Amino Acid Sequence / Base Sequence / Arachis Hypogaea / Host Plant / Plant Leaves / Biological Sciences / Molecular / Virulence / Prodrugs / Mutagenesis / Botrytis / Oxidoreductases / Laccase / Secondary Metabolites / Plant Pathogen interaction / Phenols / Botrytis cinerea / Stilbenes / Antifungal Agents / Vitis / Amino Acid Sequence / Base Sequence / Arachis Hypogaea / Host Plant / Plant Leaves
Crystal Structure of the Pregnane X Receptor-Estradiol Complex Provides Insights into Endobiotic Recognition
Molecular endocrinology / Macromolecular X-Ray Crystallography / Estrogen Receptor / Nuclear Receptor / Biological Sciences / Molecular / Crystal structure / Humans / Mutagenesis / Animals / Amino Acids / Protein Conformation / Amino Acid Sequence / Estradiol / Pregnane X Receptor / Estrogen receptor alpha / Molecular / Crystal structure / Humans / Mutagenesis / Animals / Amino Acids / Protein Conformation / Amino Acid Sequence / Estradiol / Pregnane X Receptor / Estrogen receptor alpha
Biomonitoring human exposure to environmental carcinogenic chemicals
Petroleum / Environmental Monitoring / DNA damage / Humans / Mutagenesis / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies
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