Mutagenesis

Biomonitoring human exposure to environmental carcinogenic chemicals

Petroleum / Environmental Monitoring / DNA damage / Humans / Mutagenesis / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies

High-density mutagenesis by combined DNA shuffling and phage display to assign essential amino acid residues in protein-protein interactions: application to study structure-function of plasminogen activation inhibitor 1 (PAI-I)

Molecular Biology / Recombinant DNA Technology / Protein-Protein Interaction / Humans / Mutagenesis / Sequence alignment / Mice / Animals / Epitope mapping / Phage display / Surface plasmon resonance / Monoclonal Antibodies / Shell Half-Life / Molecular cloning / Surface Area / Amino Acid Profile / High Density Concrete / Monoclonal Antibody / Tissue Plasminogen Activator / Amino Acid Substitution Rates / Structure activity Relationship / Protein Binding / D structure / Structure Function / Epitopes / Plasminogen Activator Inhibitor / Biochemistry and cell biology / Sequence alignment / Mice / Animals / Epitope mapping / Phage display / Surface plasmon resonance / Monoclonal Antibodies / Shell Half-Life / Molecular cloning / Surface Area / Amino Acid Profile / High Density Concrete / Monoclonal Antibody / Tissue Plasminogen Activator / Amino Acid Substitution Rates / Structure activity Relationship / Protein Binding / D structure / Structure Function / Epitopes / Plasminogen Activator Inhibitor / Biochemistry and cell biology

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

Genetics / Caenorhabditis elegans / Enzyme Inhibitors / Apoptosis / Gene expression / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences

Gos1p, a Saccharomyces cerevisiae SNARE protein involved in Golgi transport

Membrane Proteins / Sequence Analysis / Cell Division / Saccharomyces cerevisiae / Humans / Mutagenesis / HeLa cells / SNARE proteins / Carboxypeptidases / Membrane Protein / Recombinant Protein / Golgi Apparatus / Biochemistry and cell biology / Mutagenesis / HeLa cells / SNARE proteins / Carboxypeptidases / Membrane Protein / Recombinant Protein / Golgi Apparatus / Biochemistry and cell biology

Rel transcription factors contribute to elevated urokinase expression in human ovarian carcinoma cells

Transcription Factors / Humans / Mutagenesis / Female / Transcription Factor / European / Cell nucleus / Carcinoma / Ovarian Carcinoma / Transfection / Protein Binding / Cytoplasm / DNA binding proteins / Biochemistry and cell biology / European / Cell nucleus / Carcinoma / Ovarian Carcinoma / Transfection / Protein Binding / Cytoplasm / DNA binding proteins / Biochemistry and cell biology

Plasmid-Encoded Degradation ofp-Nitrophenol byPseudomonas cepacia

Mutagenesis / Nitrogen / Zinc / Gas Chromatography / Plasmids / Biotransformation / Burkholderia Cepacia / Thin Layer Chromatography / Biochemistry and cell biology / Mitomycin / Parathion / Biotransformation / Burkholderia Cepacia / Thin Layer Chromatography / Biochemistry and cell biology / Mitomycin / Parathion

Fidelity Variants of RNA Dependent RNA Polymerases Uncover an Indirect, Mutagenic Activity of Amiloride Compounds

Microbiology / Immunology / RNA / Medical Microbiology / Cercopithecus aethiops / Humans / Mutagenesis / Animals / HeLa cells / Genetic variation / Base Sequence / RNA Dependent RNA Polymerase / Mutagens / Vero cells / Antiviral Agents / Enterovirus / Humans / Mutagenesis / Animals / HeLa cells / Genetic variation / Base Sequence / RNA Dependent RNA Polymerase / Mutagens / Vero cells / Antiviral Agents / Enterovirus

Parallel analysis of tagged deletion mutants efficiently identifies genes involved in endoplasmic reticulum biogenesis

Microbiology / Industrial Biotechnology / Saccharomyces cerevisiae / Mutagenesis / Endoplasmic Reticulum / Genetic transformation / Yeast / Genetic transformation / Yeast

Chloroplast lysates support directed mutagenesis via modified DNA and chimeric RNA/DNA oligonucleotides

Plant Biology / DNA repair / Mutagenesis / Nucleic acid hybridization / Plant / Arabidopsis / Gene Targeting / Base Sequence / Chloroplasts / Arabidopsis / Gene Targeting / Base Sequence / Chloroplasts

Cyclophilin A peptidyl-prolyl isomerase activity promotes ZPR1 nuclear export

Biological Sciences / Saccharomyces cerevisiae / Molecular and cellular biology / Mutagenesis / C2H2 zinc fingers / Plasmids / Phenotype / Cell nucleus / Zinc Finger / Plasmids / Phenotype / Cell nucleus / Zinc Finger

REV1 and DNA polymerase zeta in DNA interstrand crosslink repair

DNA damage / DNA repair / Biological Sciences / Environmental Sciences / Mutagenesis / Genetic Recombination

RNA mutagenesis and sporadic prion diseases

RNA / Theoretical biology / RNA Editing / Prion Diseases / Biological Sciences / Humans / Mutagenesis / Mathematical Sciences / Animals / Prions / Prion disease / Humans / Mutagenesis / Mathematical Sciences / Animals / Prions / Prion disease

Clonal Conditional Mutagenesis in Malaria Parasites

Microbiology / Molecular Biology / Medical Microbiology / Gene Silencing / Mutagenesis / Animals / Promoters / Genetic Recombination / Loci / Chromosomes / Plasmodium berghei / Animals / Promoters / Genetic Recombination / Loci / Chromosomes / Plasmodium berghei

Salmonella Typhimurium resides largely as an extracellular pathogen in porcine tonsils, independently of biofilm-associated genes csgA, csgD and adrA

Microbiology / Biofilms / Veterinary Microbiology / Immunohistochemistry / Veterinary / Mutagenesis / Animals / Salmonella Typhimurium / Single Cell / Human health / Swine / Feces / Veterinary Sciences / Swine Diseases / Base Sequence / Lymph Node / Ileum / Lymph nodes / Mutagenesis / Animals / Salmonella Typhimurium / Single Cell / Human health / Swine / Feces / Veterinary Sciences / Swine Diseases / Base Sequence / Lymph Node / Ileum / Lymph nodes

Defect of Dpb2p, a noncatalytic subunit of DNA polymerase ɛ, promotes error prone replication of undamaged chromosomal DNA in Saccharomyces cerevisiae

DNA replication / Saccharomyces cerevisiae / Mutagenesis / Mutation

Specific in vivo protein-protein interactions between Escherichia coli SOS mutagenesis proteins

Bacteriology / Biological Sciences / Saccharomyces cerevisiae / Mutagenesis / Escherichia coli / Base Sequence

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