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Molecular
Molecular
Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites
Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting
Myristoyl CoA: protein N-myristoyltransferase: an essential enzyme and potential drug target in kinetoplastid parasites
Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting
Short allele dominance as a source of heterozygote deficiency at microsatellite loci: experimental evidence at the dinucleotide locus Gv1CT in Gracilaria gracilis (Rhodophyta)
Molecular Ecology / Biological Sciences / Molecular / Red Algae
A Mathematical Model for Transcriptional Interference by RNA Polymerase Traffic in Escherichia coli
Molecular Biology / RNA polymerase / Molecular / Escherichia coli / Mathematical Model / Theoretical Models / Biochemistry and cell biology / Theoretical Models / Biochemistry and cell biology
The MTIP–Myosin A Complex in Blood Stage Malaria Parasites
Molecular Biology / Calcium / Membrane Proteins / Molecular / Motility / Animals / Blood / Myosin / Plasmodium falciparum / Protozoan Proteins / Protein Binding / Biochemistry and cell biology / Animals / Blood / Myosin / Plasmodium falciparum / Protozoan Proteins / Protein Binding / Biochemistry and cell biology
Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR
Immune response / Animal Studies / Magnetic Resonance Spectroscopy / Biological Sciences / Molecular / Protein-Protein Interaction / Crystal structure / Close relationships / Stable Isotope / Animals / Epitope mapping / Antibody / Plasmodium falciparum / Red blood cell / Chemical Shift / HSQC / Monoclonal Antibody / Epitopes / Binding Site / Merozoite surface protein 1 / Protein-Protein Interaction / Crystal structure / Close relationships / Stable Isotope / Animals / Epitope mapping / Antibody / Plasmodium falciparum / Red blood cell / Chemical Shift / HSQC / Monoclonal Antibody / Epitopes / Binding Site / Merozoite surface protein 1
Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-119 mapped by TROSY NMR
Immune response / Animal Studies / Magnetic Resonance Spectroscopy / Biological Sciences / Molecular / Protein-Protein Interaction / Crystal structure / Close relationships / Stable Isotope / Animals / Epitope mapping / Antibody / Plasmodium falciparum / Red blood cell / Chemical Shift / HSQC / Monoclonal Antibody / Epitopes / Binding Site / Merozoite surface protein 1 / Protein-Protein Interaction / Crystal structure / Close relationships / Stable Isotope / Animals / Epitope mapping / Antibody / Plasmodium falciparum / Red blood cell / Chemical Shift / HSQC / Monoclonal Antibody / Epitopes / Binding Site / Merozoite surface protein 1
Prolonged Biologically Active Transgene Expression Driven by HSV Latency Active Promoter 2 (LAP2) in Brain In Vivo
Pharmacology / Technology / Gene Therapy / Gene expression / Biological Sciences / Molecular / Brain / Low Dose / Mice / Chronic Disease / Female / Animals / Therapy / Substantia nigra / Rats / Biological activity / Transgene Expression / Molecular Targeted Therapy / Parkinson Disease / Herpes Simplex Virus / Molecular / Brain / Low Dose / Mice / Chronic Disease / Female / Animals / Therapy / Substantia nigra / Rats / Biological activity / Transgene Expression / Molecular Targeted Therapy / Parkinson Disease / Herpes Simplex Virus
When dispersal fails: unexpected genetic separation in Gibraltar macaques ( Macaca sylvanus )
Genetics / Geography / Population Genetics / Molecular Evolution / Gibraltar / Morocco / Molecular Ecology / Biological Sciences / Molecular / Macaca / Mitochondrial DNA / Algeria / Female / Animals / Male / Bayes Theorem / Genetic Markers / Morocco / Molecular Ecology / Biological Sciences / Molecular / Macaca / Mitochondrial DNA / Algeria / Female / Animals / Male / Bayes Theorem / Genetic Markers
An amplified DNA element in Leishmania encodes potential integral membrane and nucleotide-binding proteins
Membrane Proteins / Biological Sciences / Molecular / Animals / Guanosine Triphosphate / Protozoan Proteins / Leishmania infantum / Amino Acid Sequence / Base Sequence / Protein Binding / Nucleotides / Adenosine Triphosphate / Protozoan Proteins / Leishmania infantum / Amino Acid Sequence / Base Sequence / Protein Binding / Nucleotides / Adenosine Triphosphate
Massively parallel 454-sequencing of fungal communities in Quercus spp. ectomycorrhizas indicates seasonal dynamics in urban and rural sites
Computational Biology / Biodiversity / Urbanization / Molecular Ecology / Biological Sciences / Molecular / Cities / Phylogeny / Quercus / Pyrosequencing / Plant Roots / Soil Microbiology / Analysis of Variance / Mycorrhizae / Seasons / Seasonal Dynamics / Ectomycorrhiza / Molecular / Cities / Phylogeny / Quercus / Pyrosequencing / Plant Roots / Soil Microbiology / Analysis of Variance / Mycorrhizae / Seasons / Seasonal Dynamics / Ectomycorrhiza
Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity
Transgenic Mice / Signal Transduction / Molecular / Cardiac Hypertrophy / Diabetes mellitus / Mice / Animals / Fatty Acid Oxidation / Peroxisome proliferator-activated receptor / Glucose Transport / Rats / Myocardium / Time Factors / Propranolol / Protein Kinase / Coronary Artery Disease / Type 2 Diabetes Mellitus / Plasma Membrane / Gene Expression Regulation / Isoproterenol / Enzyme Induction / Mice / Animals / Fatty Acid Oxidation / Peroxisome proliferator-activated receptor / Glucose Transport / Rats / Myocardium / Time Factors / Propranolol / Protein Kinase / Coronary Artery Disease / Type 2 Diabetes Mellitus / Plasma Membrane / Gene Expression Regulation / Isoproterenol / Enzyme Induction
Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity
Transgenic Mice / Signal Transduction / Molecular / Cardiac Hypertrophy / Diabetes mellitus / Mice / Animals / Fatty Acid Oxidation / Peroxisome proliferator-activated receptor / Glucose Transport / Rats / Myocardium / Time Factors / Propranolol / Protein Kinase / Coronary Artery Disease / Type 2 Diabetes Mellitus / Plasma Membrane / Gene Expression Regulation / Isoproterenol / Enzyme Induction / Mice / Animals / Fatty Acid Oxidation / Peroxisome proliferator-activated receptor / Glucose Transport / Rats / Myocardium / Time Factors / Propranolol / Protein Kinase / Coronary Artery Disease / Type 2 Diabetes Mellitus / Plasma Membrane / Gene Expression Regulation / Isoproterenol / Enzyme Induction
RNA: Prebiotic Product, or Biotic Invention?
Biochemistry / Chemistry / Organic Chemistry / RNA / Molecular / Models / Biogenesis / Nucleic Acids / RNA World / Ribonucleotides / Nucleic Acid Conformation / Ribose / Models / Biogenesis / Nucleic Acids / RNA World / Ribonucleotides / Nucleic Acid Conformation / Ribose
Correction of Laminin-5 Deficiency in Human Epidermal Stem Cells by Transcriptionally Targeted Lentiviral Vectors
Genetics / Technology / Stem Cells / Gene Therapy / Health / Stem Cell / Gene expression / Biological Sciences / Molecular / Cell Differentiation / Humans / Keratinocytes / Basement Membrane / Mice / Animals / Epidermolysis Bullosa / Lentivirus / Epidermis / Transgene Expression / Molecular Targeted Therapy / Gene Transfer / Cell Adhesion Molecules / Tissue Specificity / Skin Biopsy / Stem Cell / Gene expression / Biological Sciences / Molecular / Cell Differentiation / Humans / Keratinocytes / Basement Membrane / Mice / Animals / Epidermolysis Bullosa / Lentivirus / Epidermis / Transgene Expression / Molecular Targeted Therapy / Gene Transfer / Cell Adhesion Molecules / Tissue Specificity / Skin Biopsy
Genes encoding synthetases of cyclic depsipeptides, anabaenopeptilides, in Anabaena strain 90
Mass Spectrometry / Molecular Microbiology / Biological Sciences / Molecular / Sequence alignment / Polymerase Chain Reaction / Cyclic peptides / Substrate Specificity / Amino Acid Sequence / Anabaena / Polymerase Chain Reaction / Cyclic peptides / Substrate Specificity / Amino Acid Sequence / Anabaena
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