Molecular

Molecular Evolution in Large Genetic Networks: Does Connectivity Equal Constraint?

Evolutionary Biology / Genetics / Molecular Evolution / Cell Cycle / Energy Metabolism / Saccharomyces cerevisiae / Molecular / Escherichia coli / Power Law / Cellular Network / Evolutionary rate / Protein Interaction / Evolutionary Constraint / Amino Acid Substitution Rates / Likelihood Functions / Biochemistry and cell biology / Saccharomyces cerevisiae / Molecular / Escherichia coli / Power Law / Cellular Network / Evolutionary rate / Protein Interaction / Evolutionary Constraint / Amino Acid Substitution Rates / Likelihood Functions / Biochemistry and cell biology

Resveratrol acts as a natural profungicide and induces self-intoxication by a specific laccase

Functional Analysis / Molecular Microbiology / Molecular Genetics / Gene expression / Plant Secondary metabolite / Biological Sciences / Molecular / Virulence / Prodrugs / Mutagenesis / Botrytis / Oxidoreductases / Laccase / Secondary Metabolites / Plant Pathogen interaction / Phenols / Botrytis cinerea / Stilbenes / Antifungal Agents / Vitis / Amino Acid Sequence / Base Sequence / Arachis Hypogaea / Host Plant / Plant Leaves / Biological Sciences / Molecular / Virulence / Prodrugs / Mutagenesis / Botrytis / Oxidoreductases / Laccase / Secondary Metabolites / Plant Pathogen interaction / Phenols / Botrytis cinerea / Stilbenes / Antifungal Agents / Vitis / Amino Acid Sequence / Base Sequence / Arachis Hypogaea / Host Plant / Plant Leaves

Widespread Translocation from Autosomes to Sex Chromosomes Preserves Genetic Variability in an Endangered Lark

Evolutionary Biology / Genetics / Polymorphism / Population Genetics / Molecular Evolution / Endangered Species / Molecular / Female / Animals / Male / Sex chromosomes / Songbirds / Population Size / Comparative Analysis / Genetic variation / Genetic Variability / Chromosomes / Sex Chromosome / Biochemistry and cell biology / Endangered Species / Molecular / Female / Animals / Male / Sex chromosomes / Songbirds / Population Size / Comparative Analysis / Genetic variation / Genetic Variability / Chromosomes / Sex Chromosome / Biochemistry and cell biology

Model of Unidirectional Transluminal Gene Transfer

Technology / Gene expression / Biological Sciences / Molecular / Humans / Animals / Green Fluorescent Protein / Glycosaminoglycans / Swine / Small samples / Molecular Targeted Therapy / Peritoneum / Gene Transfer / Experimental Model / Animals / Green Fluorescent Protein / Glycosaminoglycans / Swine / Small samples / Molecular Targeted Therapy / Peritoneum / Gene Transfer / Experimental Model

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

Genetics / Mass Spectrometry / Molecular / real time PCR / Tissue culture / Amyloid Beta / Enzyme / Clinical Sciences / Amino Acid Profile / Serine Protease / Neurosciences / Senile Plaques / Amyloid Beta / Enzyme / Clinical Sciences / Amino Acid Profile / Serine Protease / Neurosciences / Senile Plaques

Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis

Thermodynamics / Molecular Biology / Protein Folding / Macromolecular X-Ray Crystallography / Molecular / Humans / Mutation / Escherichia coli / Protein structure / Structure Analysis / Anthrax / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Bacillus subtilis / Substrate Specificity / Amino Acid Sequence / Resistance Genes Mechanism) / Bacillus Anthracis / Lethal Factor / Protein Binding / Protein Data Bank / Biochemistry and cell biology / Humans / Mutation / Escherichia coli / Protein structure / Structure Analysis / Anthrax / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Bacillus subtilis / Substrate Specificity / Amino Acid Sequence / Resistance Genes Mechanism) / Bacillus Anthracis / Lethal Factor / Protein Binding / Protein Data Bank / Biochemistry and cell biology

Increased Expression of Catalase and Superoxide Dismutase 2 Reduces Cone Cell Death in Retinitis Pigmentosa

Technology / Genetic Engineering / Biological Sciences / Molecular / Mice / Retinitis pigmentosa / Animals / Cell Death / Retina / Catalase / Superoxide Dismutase / Genotype / Oxidative Damage / Molecular Targeted Therapy / Enzyme Linked Immunosorbent Assay / Superoxides / Immunoblotting / Retinitis pigmentosa / Animals / Cell Death / Retina / Catalase / Superoxide Dismutase / Genotype / Oxidative Damage / Molecular Targeted Therapy / Enzyme Linked Immunosorbent Assay / Superoxides / Immunoblotting

Neuroblastoma-targeted Nanoparticles Entrapping siRNA Specifically Knockdown ALK

Technology / Nanoparticles / Gene Silencing / Western blotting / Biological Sciences / Molecular / RNA interference / Cell line / Humans / Mice / Animals / Cell Death / Neuroblastoma / Delivery System / Anaplastic Lymphoma Kinase (ALK) / Transfection / Side Effect / Antitumor Activity / Molecular Targeted Therapy / Receptor Tyrosine Kinase / Cell Growth / Molecular / RNA interference / Cell line / Humans / Mice / Animals / Cell Death / Neuroblastoma / Delivery System / Anaplastic Lymphoma Kinase (ALK) / Transfection / Side Effect / Antitumor Activity / Molecular Targeted Therapy / Receptor Tyrosine Kinase / Cell Growth

Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer\'s disease

Genetics / Polymorphism / Molecular / Protein Aggregation / Enzyme / Clinical Sciences / Ubiquitin Proteasome System / Binary Logistic Regression / Neurosciences / Allele Frequency / Senile Plaques / Clinical Sciences / Ubiquitin Proteasome System / Binary Logistic Regression / Neurosciences / Allele Frequency / Senile Plaques

Correction of ADAMTS13 Deficiency by In Utero Gene Transfer of Lentiviral Vector encoding ADAMTS13 Genes

Technology / Fluorescence Microscopy / Gene Therapy / Western blotting / Biological Sciences / Molecular / Humans / von Willebrand factor / Mice / Female / Animals / Lentivirus / Immunoprecipitation / Gestational Age / Carotid Artery / Uterus / Thrombotic Thrombocytopenic Purpura / Molecular Targeted Therapy / Full Length Movies / Gene Transfer / Molecular / Humans / von Willebrand factor / Mice / Female / Animals / Lentivirus / Immunoprecipitation / Gestational Age / Carotid Artery / Uterus / Thrombotic Thrombocytopenic Purpura / Molecular Targeted Therapy / Full Length Movies / Gene Transfer

Estradiol activates mast cells via a non-genomic estrogen receptor-α and calcium influx

Immunology / Asthma / Mast Cells / Molecular Mechanics / Estrogen Receptor / Molecular / Cell line / Molecular Immunology / Humans / Mice / Female / Animals / Male / Calcium Signaling / Allergens / Immunoglobulin E / Rats / Estradiol / Estrogen receptor alpha / Molecular / Cell line / Molecular Immunology / Humans / Mice / Female / Animals / Male / Calcium Signaling / Allergens / Immunoglobulin E / Rats / Estradiol / Estrogen receptor alpha

Phylogeography and postglacial expansion of Mus musculus domesticus inferred from mitochondrial DNA coalescent, from Iran to Europe

Geography / Population Genetics / Iran / Molecular Ecology / Biological Sciences / Molecular / Phylogeny / Mitochondrial DNA / Europe / Mice / Animals / Genetic variation / Molecular / Phylogeny / Mitochondrial DNA / Europe / Mice / Animals / Genetic variation

Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice

Immunohistochemistry / Gene expression / Western blotting / Transgenic Mice / Heart Failure / Molecular / Cardiac Hypertrophy / Brain / Mice / Animals / Polymerase Chain Reaction / Heart / Current Density / Myocardium / Time Dependent / Western blot / Chloride Channel / Ejection Fraction / Gene Family / Regulatory volume decrease / Cell Volume / Whole cell Patch-Clamp / Knock Out Mice / Molecular / Cardiac Hypertrophy / Brain / Mice / Animals / Polymerase Chain Reaction / Heart / Current Density / Myocardium / Time Dependent / Western blot / Chloride Channel / Ejection Fraction / Gene Family / Regulatory volume decrease / Cell Volume / Whole cell Patch-Clamp / Knock Out Mice

Chloroplast DNA variation and postglacial recolonization of common ash (Fraxinus excelsior L.) in Europe

Genetics / Polymorphism / Molecular Ecology / Biological Sciences / Molecular / Phylogeny / Europe / South Eastern Europe / Pollen / Haplotypes / Fossils / Population History / Polymerase Chain Reaction / Effective Population Size / Fraxinus / Glacial Refugia / Genetic variation / Wind Pollination / Environment / Genetic Markers / Mutation Rate / Phylogeny / Europe / South Eastern Europe / Pollen / Haplotypes / Fossils / Population History / Polymerase Chain Reaction / Effective Population Size / Fraxinus / Glacial Refugia / Genetic variation / Wind Pollination / Environment / Genetic Markers / Mutation Rate

The Escherichia coli YadB Gene Product Reveals a Novel Aminoacyl-tRNA Synthetase Like Activity

Molecular Biology / Kinetics / Structural Genomics / Macromolecular X-Ray Crystallography / Molecular / Glutamate / Escherichia coli / Zinc / Amino Acid Profile / Protein Conformation / Amino Acid Sequence / Open Reading Frame / Gene Family / aminoacyl-tRNA synthetase / Molecular Replacement / Ligands / Glutamic Acid / Biochemistry and cell biology / Adenosine Triphosphate / Adenosine monophosphate / Glutamate / Escherichia coli / Zinc / Amino Acid Profile / Protein Conformation / Amino Acid Sequence / Open Reading Frame / Gene Family / aminoacyl-tRNA synthetase / Molecular Replacement / Ligands / Glutamic Acid / Biochemistry and cell biology / Adenosine Triphosphate / Adenosine monophosphate

Adeno-associated virus vector serotypes mediate sustained correction of bilirubin UDP glucuronosyltransferase deficiency in rats

Technology / Gene Therapy / Biological Sciences / Molecular / Liver / Animals / Gene transfer techniques / Polymerase Chain Reaction / Adeno-associated virus / Bilirubin / Rats / First Year / Crigler-Najjar syndrome / Rat Model / Molecular Targeted Therapy / Brain Damage / Serotyping / Bile / Animals / Gene transfer techniques / Polymerase Chain Reaction / Adeno-associated virus / Bilirubin / Rats / First Year / Crigler-Najjar syndrome / Rat Model / Molecular Targeted Therapy / Brain Damage / Serotyping / Bile
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