Molecular Mechanics

Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension

Physiology / Oxidative Stress / Apoptosis / Gene expression / Pulmonary Hypertension / Probability / Molecular Mechanics / Western blotting / Heart Failure / Cardiac Hypertrophy / Anoxia / Hypertension / Low Dose / Reactive Oxygen Species / Mice / Left Ventricular Assist Device / Blood Pressure / Aldosterone / Renin Angiotensin Aldosterone System / Animals / Male / Cytochrome C / Glutathione / American / Phosphorylation / Fibrosis / Lipid metabolism / Medical Physiology / NADPH oxidase / Clinical Sciences / Chronic Renal Failure / Urinalysis / Protein kinase B / mRna expression levels / Rats / Analysis of Variance / Cardiac Output Monitoring / Left ventricular hypertrophy / Body Weight / Biological markers / Right Ventricle / Albuminuria / Cell Proliferation / Ventricular Remodeling / Angiotensin II / Ct Image of Pulmonary Artery / Vascular Injury / Heart Ventricles / Cell Survival / Nephrectomy / Mineralocorticoid Receptor / Podocytes / Glucocorticoids / Left Ventricle / Brain Natriuretic Peptide / Systolic blood pressure / Vascular Resistance / Probability / Molecular Mechanics / Western blotting / Heart Failure / Cardiac Hypertrophy / Anoxia / Hypertension / Low Dose / Reactive Oxygen Species / Mice / Left Ventricular Assist Device / Blood Pressure / Aldosterone / Renin Angiotensin Aldosterone System / Animals / Male / Cytochrome C / Glutathione / American / Phosphorylation / Fibrosis / Lipid metabolism / Medical Physiology / NADPH oxidase / Clinical Sciences / Chronic Renal Failure / Urinalysis / Protein kinase B / mRna expression levels / Rats / Analysis of Variance / Cardiac Output Monitoring / Left ventricular hypertrophy / Body Weight / Biological markers / Right Ventricle / Albuminuria / Cell Proliferation / Ventricular Remodeling / Angiotensin II / Ct Image of Pulmonary Artery / Vascular Injury / Heart Ventricles / Cell Survival / Nephrectomy / Mineralocorticoid Receptor / Podocytes / Glucocorticoids / Left Ventricle / Brain Natriuretic Peptide / Systolic blood pressure / Vascular Resistance

Implicaciones del nuevo enfoque etiopatogénico en la clasificación de las enfermedades constitucionales y genéticas del hueso

Genetics / Control system / Molecular Mechanics / Humans / Genetic Analysis / Metabolic pathway / Interdisciplinary Collaboration / Metabolic pathway / Interdisciplinary Collaboration

E-cadherin controls  -catenin and NF- B transcriptional activity in mesenchymal gene expression

Cell Adhesion / Transcription Factors / Gene expression / Molecular Mechanics / Biological Sciences / Cell line / Humans / NF-kappa B / Beta-Catenin / Gene Expression Regulation / Cell line / Humans / NF-kappa B / Beta-Catenin / Gene Expression Regulation

Hydrogen peroxide-induced oxidative stress responses in Desulfovibrio vulgaris Hildenborough

Genetics / Microbiology / Environmental microbiology / Network Analysis / Oxidative Stress / DNA repair / Gene expression / Molecular Mechanics / Protein synthesis / Signal Transduction / Stress response / Detoxification / Sulfate reducing Bacteria / Hydrogen Peroxide / Cellular Automaton Model / Thioredoxin / Sulfate reduction / Proteome / Environmental / Sulphate Reducing Bacteria / Oxidants / DNA repair / Gene expression / Molecular Mechanics / Protein synthesis / Signal Transduction / Stress response / Detoxification / Sulfate reducing Bacteria / Hydrogen Peroxide / Cellular Automaton Model / Thioredoxin / Sulfate reduction / Proteome / Environmental / Sulphate Reducing Bacteria / Oxidants

KF-1 Ubiquitin Ligase: Anxiety Suppressor Model

Anxiety Disorders / Gene expression / Prefrontal Cortex / Molecular Mechanics / Signal Transduction / Phylogeny / Hippocampus / Humans / Mice / Animals / Endoplasmic Reticulum / Frontal Cortex / Amygdala / National Culture / Rats / Ubiquitin ligase / Environmental Stress / Amino Acid Sequence / Anxiety Disorder / Biochemistry and cell biology / Phylogeny / Hippocampus / Humans / Mice / Animals / Endoplasmic Reticulum / Frontal Cortex / Amygdala / National Culture / Rats / Ubiquitin ligase / Environmental Stress / Amino Acid Sequence / Anxiety Disorder / Biochemistry and cell biology

Topoisomerase Poisoning Activity of Novel Disaccharide Anthracyclines

Molecular Pharmacology / Molecular Mechanics / Cell Division / Saccharomyces cerevisiae / Humans / Enzyme / Doxorubicin / Base Sequence / Antitumor Activity / Structure Determination / Neurosciences / Anticancer Drug / Enzyme / Doxorubicin / Base Sequence / Antitumor Activity / Structure Determination / Neurosciences / Anticancer Drug

Periventricular heterotopia: new insights into Ehlers-Danlos syndrome

Genetics / Risk / Molecular Mechanics / Brain / Humans / Mutation / Cerebral Cortex / Collagen / Clinical Medicine / Connective tissue / Central Nervous System / Neurons / Phenotype / Cortical Development / Clinical Sciences / Ehlers-Danlos Syndrome / Neuronal Migration / Aortic Dissection / Contractile Proteins / Brain Diseases / Cell Motility / Mutation / Cerebral Cortex / Collagen / Clinical Medicine / Connective tissue / Central Nervous System / Neurons / Phenotype / Cortical Development / Clinical Sciences / Ehlers-Danlos Syndrome / Neuronal Migration / Aortic Dissection / Contractile Proteins / Brain Diseases / Cell Motility

Protein Kinase A Activation Promotes Plasma Membrane Insertion of DCC from an Intracellular Pool: A Novel Mechanism Regulating Commissural Axon Extension

Neuroscience / Enzyme Inhibitors / Molecular Mechanics / cyclic AMP / Animals / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth

Gene Expression Profiles in a Transgenic Animal Model of Fragile X Syndrome

Neurobiology Of Disease / Neurobiology / Molecular Mechanics / Mental Retardation / Brain / Mice / Female / Animals / Male / Animal Model / Fragile X Syndrome / Amyloid Beta / Spatial Distribution / Clinical Sciences / Knockout Mice / Neurosciences / Microarray Data / Gene expression profiling / Amyloid Beta Precursor Protein / Mice / Female / Animals / Male / Animal Model / Fragile X Syndrome / Amyloid Beta / Spatial Distribution / Clinical Sciences / Knockout Mice / Neurosciences / Microarray Data / Gene expression profiling / Amyloid Beta Precursor Protein

Animal models of portal hypertension

Microcirculation / Molecular Mechanics / Dogs / Portal hypertension / Liver / World / Mice / Nitric oxide / Animals / Animal Model / Clinical Sciences / Rats / Swine / Rabbits / Portal vein / World / Mice / Nitric oxide / Animals / Animal Model / Clinical Sciences / Rats / Swine / Rabbits / Portal vein

Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice

Aging / Molecular Mechanics / Transgenic Mice / Biological Sciences / Learning and Memory / Humans / Mice / Animals / Cell Death / Acetylcholinesterase / Open Field / Central Nervous System / Animal Model / Acetylcholine / Spatial Learning / Neurons / Cholinesterase inhibitors / Structural Change / Enzyme / Locomotor Activity / Neuromuscular Junction / Transgene Expression / Cognition disorders / Water maze / Humans / Mice / Animals / Cell Death / Acetylcholinesterase / Open Field / Central Nervous System / Animal Model / Acetylcholine / Spatial Learning / Neurons / Cholinesterase inhibitors / Structural Change / Enzyme / Locomotor Activity / Neuromuscular Junction / Transgene Expression / Cognition disorders / Water maze

How do bifidobacteria counteract environmental challenges? Mechanisms involved and physiological consequences

Molecular Mechanics / Water Activity / Biological activity / Carbon Source / Small Intestine

CD36 Deficiency Leads to Choroidal Involution via COX2 Down-Regulation in Rodents

Retinal Pigment Epithelium / Molecular Mechanics / Mice / Animals / Retinal Degeneration / Age related macular degeneration / Rats / Degeneration / Wistar Rats / Spontaneously Hypertensive Rat / Vascular Endothelial Growth Factor / Down-Regulation / Age related macular degeneration / Rats / Degeneration / Wistar Rats / Spontaneously Hypertensive Rat / Vascular Endothelial Growth Factor / Down-Regulation

Estradiol activates mast cells via a non-genomic estrogen receptor-α and calcium influx

Immunology / Asthma / Mast Cells / Molecular Mechanics / Estrogen Receptor / Molecular / Cell line / Molecular Immunology / Humans / Mice / Female / Animals / Male / Calcium Signaling / Allergens / Immunoglobulin E / Rats / Estradiol / Estrogen receptor alpha / Molecular / Cell line / Molecular Immunology / Humans / Mice / Female / Animals / Male / Calcium Signaling / Allergens / Immunoglobulin E / Rats / Estradiol / Estrogen receptor alpha

An ex-vivo Human Intestinal Model to Study Entamoeba histolytica Pathogenesis

Cytokines / Scanning Electron Microscopy / Molecular Mechanics / Biological Sciences / Inflammatory Immune Response / Humans / Female / Animals / Male / Cell Death / Aged / Middle Aged / Entamoeba histolytica / Virulence factor / Colon / Light chain / Interferon gamma / Humans / Female / Animals / Male / Cell Death / Aged / Middle Aged / Entamoeba histolytica / Virulence factor / Colon / Light chain / Interferon gamma

Optimal control design of laser pulses for mode specific vibrational excitation in an enzyme–substrate complex

Technology / Optimal Control / Quantum Mechanics / Molecular Mechanics / Optimal Control theory / Physical sciences / Enzyme / CHEMICAL SCIENCES / Excited states / Potential Energy / Physical sciences / Enzyme / CHEMICAL SCIENCES / Excited states / Potential Energy
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