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Molecular Mechanics
Molecular Mechanics
Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice
Aging / Molecular Mechanics / Transgenic Mice / Biological Sciences / Learning and Memory / Humans / Mice / Animals / Cell Death / Acetylcholinesterase / Open Field / Central Nervous System / Animal Model / Acetylcholine / Spatial Learning / Neurons / Cholinesterase inhibitors / Structural Change / Enzyme / Locomotor Activity / Neuromuscular Junction / Transgene Expression / Cognition disorders / Water maze / Humans / Mice / Animals / Cell Death / Acetylcholinesterase / Open Field / Central Nervous System / Animal Model / Acetylcholine / Spatial Learning / Neurons / Cholinesterase inhibitors / Structural Change / Enzyme / Locomotor Activity / Neuromuscular Junction / Transgene Expression / Cognition disorders / Water maze
General Palaeontology (Palaeobiochemistry) Biomineralisation in reef-building corals: from molecular mechanisms to environmental control
Molecular Mechanics / Environmental Control / Coral Reef / Environmental Parameter
C. elegans: a novel pharmacogenetic model to study Parkinson\'s disease
Genetics / Cognitive Science / Caenorhabditis elegans / Molecular Mechanics / Protein-Protein Interaction / Tissue culture / Clinical Sciences / Dopamine Transporter / Model System / Degeneration / Genetic Analysis / Metabolic pathway / Drug Targeting / Substantia nigra pars compacta (SNpc) / Tissue culture / Clinical Sciences / Dopamine Transporter / Model System / Degeneration / Genetic Analysis / Metabolic pathway / Drug Targeting / Substantia nigra pars compacta (SNpc)
C1-inhibitor deficiency and angioedema: molecular mechanisms and clinical progress
Molecular Mechanics / Biological Sciences / Humans / Homeostasis / Angioedema / Bradykinin
How do bifidobacteria counteract environmental challenges? Mechanisms involved and physiological consequences
Molecular Mechanics / Water Activity / Biological activity / Carbon Source / Small Intestine
Transcriptional activation of polycomb-repressed genes by ZRF1
Multidisciplinary / Gene Silencing / Nature / Molecular Mechanics / Cell line / Humans / Chromatin / Histones / Cell Fate / DNA binding proteins / Polycomb group proteins / Gene Expression Regulation / Humans / Chromatin / Histones / Cell Fate / DNA binding proteins / Polycomb group proteins / Gene Expression Regulation
UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells
Leukemia / Apoptosis / Molecular Mechanics / Cell line / Humans / Congestive Heart Failure / Cell Death / Biochemical / BIOCHEMICAL PHARMACOLOGY / Molecular Structure / Congestive Heart Failure / Cell Death / Biochemical / BIOCHEMICAL PHARMACOLOGY / Molecular Structure
Linear Artificial Molecular Muscles
Electrochemistry / Self Assembly / NMR Spectroscopy / Cyclic Voltammetry / Molecular Mechanics / Muscles / The / CHEMICAL SCIENCES / Rotaxanes / Skeletal Muscle / Room Temperature / Biomimetic materials / Spectrum analysis / Length scale / Low Temperature / Static Electricity / Molecular Structure / Cumulant / Muscles / The / CHEMICAL SCIENCES / Rotaxanes / Skeletal Muscle / Room Temperature / Biomimetic materials / Spectrum analysis / Length scale / Low Temperature / Static Electricity / Molecular Structure / Cumulant
Glutamate NMDA receptor subunit R1 and GAD mRNA expression in human temporal lobe epilepsy
Molecular Mechanics / Hippocampus / Glutamate / Molecular and cellular biology / Humans / Cellular and Molecular Neurobiology / Female / Male / Temporal Lobe Epilepsy / Synaptic Transmission / Neurons / Middle Aged / mRna expression levels / Adult / Isoenzymes / Neurosciences / Glutamate decarboxylase / Gamma-Aminobutyric Acid / Biochemistry and cell biology / Cellular and Molecular Neurobiology / Female / Male / Temporal Lobe Epilepsy / Synaptic Transmission / Neurons / Middle Aged / mRna expression levels / Adult / Isoenzymes / Neurosciences / Glutamate decarboxylase / Gamma-Aminobutyric Acid / Biochemistry and cell biology
How do bifidobacteria counteract environmental challenges? Mechanisms involved and physiological consequences
Molecular Mechanics / Water Activity / Biological activity / Carbon Source / Small Intestine
Protein Kinase A Activation Promotes Plasma Membrane Insertion of DCC from an Intracellular Pool: A Novel Mechanism Regulating Commissural Axon Extension
Neuroscience / Enzyme Inhibitors / Molecular Mechanics / cyclic AMP / Animals / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Cell Surface Markers / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Cell Surface Markers / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth
Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension
Neuroscience / Enzyme Inhibitors / Molecular Mechanics / cyclic AMP / Animals / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Cell Surface Markers / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Cell Surface Markers / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth
Gene expression profiling in vLINCL CLN6-deficient fibroblasts: Insights into pathobiology
Membrane Proteins / Extracellular Matrix / Molecular Mechanics / Biological Sciences / Inflammatory Immune Response / Humans / Cell Mechanics / Cholesterol / Cell Death / Physical sciences / Statistical Significance / Signal Transduction Pathway Models / Clinical Sciences / Lipid Raft / Neurodegenerative Disease / Cdna Microarray / Human Fibroblasts / Structure Function / Biochemistry and cell biology / Gene expression profiling / Humans / Cell Mechanics / Cholesterol / Cell Death / Physical sciences / Statistical Significance / Signal Transduction Pathway Models / Clinical Sciences / Lipid Raft / Neurodegenerative Disease / Cdna Microarray / Human Fibroblasts / Structure Function / Biochemistry and cell biology / Gene expression profiling
CD36 Deficiency Leads to Choroidal Involution via COX2 Down-Regulation in Rodents
Retinal Pigment Epithelium / Molecular Mechanics / Mice / Animals / Retinal Degeneration / Age related macular degeneration / Rats / Degeneration / Wistar Rats / Spontaneously Hypertensive Rat / Vascular Endothelial Growth Factor / Down-Regulation / Age related macular degeneration / Rats / Degeneration / Wistar Rats / Spontaneously Hypertensive Rat / Vascular Endothelial Growth Factor / Down-Regulation
The class E floral homeotic protein SEPALLATA3 is sufficient to loop DNA in \'floral quartet\'-like complexes in vitro
Transcription Factors / Molecular Mechanics / Arabidopsis thaliana / Biological Sciences / Protein-Protein Interaction / Environmental Sciences / Nucleic Acids / Transcription Factor / DNA binding / Protein Binding / Nucleic Acid Conformation / Environmental Sciences / Nucleic Acids / Transcription Factor / DNA binding / Protein Binding / Nucleic Acid Conformation
Structural and functional characterisation of an influenza virus RNA polymerase-genomic RNA complex
Microbiology / Zoology / Immunology / Molecular Biology / Structural Biology / Biomaterials / Tissue Engineering / Medical Microbiology / Virology / Wastewater Treatment / Hydrogels / Transcription Factors / Multidisciplinary / Extracellular Matrix / Animal Production / Molecular Mechanics / Enzyme Kinetics / Immunogenetics / Catalytic Mechanism / Biological Sciences / Protein Structure and Function / Crystal structure / Molecular Immunology / Heparin / Sequence alignment / Basement Membrane / Biological Wastewater Treatment / Mice / Animals / Blood / Polymerase Chain Reaction / Physical sciences / Special functions / Detoxification / Fisheries Sciences / Fibroblast Growth Factor / Glycosaminoglycan / Transcription Factor / Enzyme / Clinical Sciences / Active site / Polyvinyl alcohol / Poly Vinyl Alcohol / Amino Acid Profile / Veterinary Sciences / Biological activity / Amino Acid Sequence / Base Sequence / Materials Testing / Growth Factor / Structure activity Relationship / Protein Binding / D structure / Biocompatible Materials / Cell Surface Markers / Cardiovascular Magnetic Resonance / Site-directed Mutagenesis / Binding Site / Biochemistry and cell biology / Biomechanical Phenomena / Biomaterials / Tissue Engineering / Medical Microbiology / Virology / Wastewater Treatment / Hydrogels / Transcription Factors / Multidisciplinary / Extracellular Matrix / Animal Production / Molecular Mechanics / Enzyme Kinetics / Immunogenetics / Catalytic Mechanism / Biological Sciences / Protein Structure and Function / Crystal structure / Molecular Immunology / Heparin / Sequence alignment / Basement Membrane / Biological Wastewater Treatment / Mice / Animals / Blood / Polymerase Chain Reaction / Physical sciences / Special functions / Detoxification / Fisheries Sciences / Fibroblast Growth Factor / Glycosaminoglycan / Transcription Factor / Enzyme / Clinical Sciences / Active site / Polyvinyl alcohol / Poly Vinyl Alcohol / Amino Acid Profile / Veterinary Sciences / Biological activity / Amino Acid Sequence / Base Sequence / Materials Testing / Growth Factor / Structure activity Relationship / Protein Binding / D structure / Biocompatible Materials / Cell Surface Markers / Cardiovascular Magnetic Resonance / Site-directed Mutagenesis / Binding Site / Biochemistry and cell biology / Biomechanical Phenomena
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