Mitochondria

Mitochondrial control of autophagic lysosomal pathway in Alzheimer\'s disease

Psychology / Oxidative Stress / Mitochondria / Autophagy / Energy Metabolism / Brain / Humans / Protein Aggregation / Clinical Sciences / Mitochondrial dysfunction / Experimental / Experimental Neurology / Lysosomes / Alzheimer Disease / Cell Survival / Neurosciences / Macroautophagy / Brain / Humans / Protein Aggregation / Clinical Sciences / Mitochondrial dysfunction / Experimental / Experimental Neurology / Lysosomes / Alzheimer Disease / Cell Survival / Neurosciences / Macroautophagy

Knockdown of Hsc70-5/mortalin Induces Loss of Synaptic Mitochondria in a Drosophila Parkinson’s Disease Model

Engineering / Physics / Chemistry / Biology / Mitochondria / Autophagy / Medicine / Multidisciplinary / Gene Silencing / Drosophila / Humans / Female / Animals / Neurons / Phenotype / PLoS one / SYNAPSES / Cell Survival / Dopaminergic Neurons / Parkinson Disease / Autophagy / Medicine / Multidisciplinary / Gene Silencing / Drosophila / Humans / Female / Animals / Neurons / Phenotype / PLoS one / SYNAPSES / Cell Survival / Dopaminergic Neurons / Parkinson Disease

Mitochondrial membrane potential in density-separated trout erythrocytes exposed to oxidative stress in vitro

Free Radicals / Flow Cytometry / Oxidative Stress / Mitochondria / Fluorescent Dyes and Reagents / Confocal Microscopy / Biological Sciences / Antioxidants / Reactive Oxygen Species / Animals / Physical sciences / Glutathione Peroxidase / Organoselenium Compounds / Fluorescent probes / Trout / Benzimidazoles / Membrane Potential / Erythrocytes / Mitochondrial Membrane Potential / Biochemistry and cell biology / Molecular Structure / Confocal Microscopy / Biological Sciences / Antioxidants / Reactive Oxygen Species / Animals / Physical sciences / Glutathione Peroxidase / Organoselenium Compounds / Fluorescent probes / Trout / Benzimidazoles / Membrane Potential / Erythrocytes / Mitochondrial Membrane Potential / Biochemistry and cell biology / Molecular Structure

Novel Conjugated Quinoline–Indoles Compromise Plasmodium falciparum Mitochondrial Function and Show Promising Antimalarial Activity

Organic Chemistry / Medicinal Chemistry / Mitochondria / Humans / Drug Resistance / Plasmodium falciparum / Antimalarials / Chloroquine / Structure activity Relationship / Hemoglobins / Plasmodium falciparum / Antimalarials / Chloroquine / Structure activity Relationship / Hemoglobins

Intraspecific Genetic Variation in Paramecium Revealed by Mitochondrial Cytochrome c Oxidase I Sequences

Microbiology / Zoology / Mitochondria / Mitochondrial DNA / Animals / Cytochrome c oxidase / Genetic variation / Eukaryotic microbiology / Paramecium / Cytochrome c oxidase / Genetic variation / Eukaryotic microbiology / Paramecium

Cell-Permeable Gomesin Peptide Promotes Cell Death by Intracellular Ca 2+ Overload

Calcium / Mitochondria / Signal Transduction / Cell line / Reactive Oxygen Species / Animals / Cell Death / Endoplasmic Reticulum / Antimicrobial Cationic Peptides / Cytoplasm / Molecular Pharmaceutics / Animals / Cell Death / Endoplasmic Reticulum / Antimicrobial Cationic Peptides / Cytoplasm / Molecular Pharmaceutics

Steatosis-Induced Proteomic Changes in Liver Mitochondria Evidenced by Two-Dimensional Differential In-Gel Electrophoresis

Mass Spectrometry / Proteomics / Oxidative Stress / Mitochondria / Biological Sciences / Liver / Fatty acids / Mice / Animals / Male / Lipid peroxidation / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Fatty Liver / Hepatocytes / Peroxisomes / Gel electrophoresis / Two-Dimensional Gel Electrophoresis / Proteome / Adenosine Triphosphate / Liver / Fatty acids / Mice / Animals / Male / Lipid peroxidation / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Fatty Liver / Hepatocytes / Peroxisomes / Gel electrophoresis / Two-Dimensional Gel Electrophoresis / Proteome / Adenosine Triphosphate

Characterization of Membrane Potential Dependency of Mitochondrial Ca2+ Uptake by an Improved Biophysical Model of Mitochondrial Ca2+ Uniporter

Biophysics / Calcium / Mitochondria / Multidisciplinary / Humans / Mice / Animals / Calcium channels / Organophosphorus Compounds / Non small cell carcinoma / PLoS one / Clinical Sciences / Theoretical Models / Mice / Animals / Calcium channels / Organophosphorus Compounds / Non small cell carcinoma / PLoS one / Clinical Sciences / Theoretical Models

New mitochondrial and nuclear evidences support recent demographic expansion and an atypical phylogeographic pattern in the spittlebug Philaenus spumarius (Hemiptera, Aphrophoridae)

Demography / Phylogeography / Mitochondria / Multidisciplinary / Phylogeny / Mitochondrial DNA / Humans / Haplotypes / Animals / Population Growth / Hemiptera / PLoS one / Cell nucleus / Time Factors / Genetic variation / Likelihood Functions / Mitochondrial DNA / Humans / Haplotypes / Animals / Population Growth / Hemiptera / PLoS one / Cell nucleus / Time Factors / Genetic variation / Likelihood Functions

TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency

Mitochondria / Animals / Microglia / Clinical Sciences / Mitochondrial Diseases / Larva / Zebrafish / Neurosciences / Dopaminergic Neurons / Parkinson Disease / Larva / Zebrafish / Neurosciences / Dopaminergic Neurons / Parkinson Disease

Mitochondrial complex I impairment in leukocytes from type 2 diabetic patients

Oxidative Stress / Mitochondria / Free Radical / Insulin Resistance / Humans / Reactive Oxygen Species / Female / Clinical / Body Composition / Glutathione / Homocysteine / Waist Circumference / Clinical Sciences / Polycystic Ovary Syndrome / Middle Aged / C reactive protein / Oxygen / Tumor necrosis factor-alpha / Type 2 Diabetes Mellitus / Mitochondrial Membrane Potential / Oxygen Consumption / Leukocytes / Biochemistry and cell biology / Reactive Oxygen Species / Female / Clinical / Body Composition / Glutathione / Homocysteine / Waist Circumference / Clinical Sciences / Polycystic Ovary Syndrome / Middle Aged / C reactive protein / Oxygen / Tumor necrosis factor-alpha / Type 2 Diabetes Mellitus / Mitochondrial Membrane Potential / Oxygen Consumption / Leukocytes / Biochemistry and cell biology

PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

Skeletal muscle biology / Oxidative Stress / Mitochondria / DNA damage / Energy Metabolism / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology

PARP1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

Skeletal muscle biology / Oxidative Stress / Mitochondria / DNA damage / Energy Metabolism / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology

Isolation of functional pure mitochondria by superparamagnetic microbeads

Analytical Chemistry / Flow Cytometry / Membrane Proteins / Mitochondria / Cell separation / Magnetic field / Antibodies / Humans / Magnetic separation / Magnetics / Gel electrophoresis / Microspheres / Analytical Biochemistry / Membrane Protein / Physicochemical Properties / Biochemistry and cell biology / Mitochondrial Proteins / Magnetic field / Antibodies / Humans / Magnetic separation / Magnetics / Gel electrophoresis / Microspheres / Analytical Biochemistry / Membrane Protein / Physicochemical Properties / Biochemistry and cell biology / Mitochondrial Proteins

Central carbon metabolism of Leishmania parasites

Parasitology / Metabolism / Carbon / Mass Spectrometry / Metabolomics / Mitochondria / Leishmania / Leishmaniasis / Humans / Parasite / Animals / Parasites / Host-parasite interactions / Carbohydrate metabolism / Carbon Metabolism / Veterinary Sciences / Intracellular Space / Mitochondria / Leishmania / Leishmaniasis / Humans / Parasite / Animals / Parasites / Host-parasite interactions / Carbohydrate metabolism / Carbon Metabolism / Veterinary Sciences / Intracellular Space

 -Synuclein Controls Mitochondrial Calcium Homeostasis by Enhancing Endoplasmic Reticulum-Mitochondria Interactions

Calcium / Mitochondria / Biological Chemistry / Alpha Synuclein / Biological Sciences / Humans / Polymerase Chain Reaction / Endoplasmic Reticulum / CHEMICAL SCIENCES / Homeostasis / Base Sequence / Subcellular Fractions / Humans / Polymerase Chain Reaction / Endoplasmic Reticulum / CHEMICAL SCIENCES / Homeostasis / Base Sequence / Subcellular Fractions
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