Mechanism of action

Octreotide effectively decreases mucosal damage in experimental colitis

Inflammatory Immune Response / Inflammatory Bowel Disease / Intestinal Mucosa / Animals / Male / Clinical Sciences / Colitis / Rats / Vasoactive Intestinal Peptide / Gut / Acetic Acid / Mechanism of action / Colon / Calcitonin Gene-Related Peptide / Clinical Sciences / Colitis / Rats / Vasoactive Intestinal Peptide / Gut / Acetic Acid / Mechanism of action / Colon / Calcitonin Gene-Related Peptide

Ultra-Low-Dose Opioid Antagonists Enhance Opioid Analgesia and Reduce Tolerance

Low Dose / Neuropathic pain / Mu Opioid Receptor / Clinical Study / Controlled Clinical Trial / Mechanism of action

Recomendaciones sobre ranelato de estroncio en el tratamiento de la osteoporosis

Older Women / Bone Mineral Density / Bone Formation / Mechanism of action / Bone Resorption

Prenatal exposure to serotonin reuptake inhibitors: a case report

Depression / Pregnancy / Case Report / Humans / Low Birth Weight / Female / Follow-up studies / Depressive Disorder / Newborn Infant / Mechanism of action / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Female / Follow-up studies / Depressive Disorder / Newborn Infant / Mechanism of action / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor

Recomendaciones sobre ranelato de estroncio en el tratamiento de la osteoporosis

Older Women / Bone Mineral Density / Bone Formation / Mechanism of action / Bone Resorption

Fentanyl–trazodone–paracetamol triple drug combination: Multimodal analgesia in a mouse model of visceral pain

Pharmacology / Pain / Chronic Pain / Mice / Animals / Motor Coordination / Male / Synergy / Mouse Model / Acetic Acid / Acetaminophen / Mechanism of action / Opioid Receptor / Drug Interaction / Fixed Ratio / Fentanyl / Analgesics / Drug treatment / Motor Coordination / Male / Synergy / Mouse Model / Acetic Acid / Acetaminophen / Mechanism of action / Opioid Receptor / Drug Interaction / Fixed Ratio / Fentanyl / Analgesics / Drug treatment

Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency

Multidisciplinary / Humans / Cell fusion / Mice / Cholesterol / Animals / Drug Delivery Systems / Lipid Raft / Shell Half-Life / Viral Infection / HeLa cells / Heptad Repeat / Lipid Rafts / Mechanism of action / Antiviral Activity / Structure activity Relationship / Animals / Drug Delivery Systems / Lipid Raft / Shell Half-Life / Viral Infection / HeLa cells / Heptad Repeat / Lipid Rafts / Mechanism of action / Antiviral Activity / Structure activity Relationship

APOE-Mimetic Peptides Reduce Behavioral Deficits, Plaques and Tangles in Alzheimer’s Disease Transgenics

Cognitive Science / Neurodegenerative Diseases / Neuroprotection / Transgenic Mice / Amyloid / Brain / Humans / Mutation / Mice / Animals / Apolipoprotein E / Risk factors / Clinical Sciences / Time Factors / Transforming Growth Factor Beta / Risk Factors / Anti Inflammatory Activity / Mechanism of action / Neurofibrillary Tangles / Alzheimer Disease / Maze Learning / Neurosciences / Gene Expression Regulation / Head Trauma / Interleukin / Dephosphorylation / Amyloid Beta Precursor Protein / Behavioral symptoms / Motor activity / Brain / Humans / Mutation / Mice / Animals / Apolipoprotein E / Risk factors / Clinical Sciences / Time Factors / Transforming Growth Factor Beta / Risk Factors / Anti Inflammatory Activity / Mechanism of action / Neurofibrillary Tangles / Alzheimer Disease / Maze Learning / Neurosciences / Gene Expression Regulation / Head Trauma / Interleukin / Dephosphorylation / Amyloid Beta Precursor Protein / Behavioral symptoms / Motor activity

Low-Dose Lidocaine Reduces Secondary Hyperalgesia by a Central Mode of Action

Pain / Humans / Low Dose / Neuropathic pain / Female / Male / Central Nervous System / The / Capsaicin / Middle Aged / Mode of action / Adult / Sodium channel / Lidocaine / Mechanism of action / Axons / Neurosciences / Pain Measurement / Time Course / Hyperalgesia / Laser Doppler Flowmetry / Male / Central Nervous System / The / Capsaicin / Middle Aged / Mode of action / Adult / Sodium channel / Lidocaine / Mechanism of action / Axons / Neurosciences / Pain Measurement / Time Course / Hyperalgesia / Laser Doppler Flowmetry

Cardiac Sympathetic Denervation After Transmyocardial Laser Revascularization

Humans / PET imaging / Female / Male / Myocardial Revascularization / Denervation / Clinical Sciences / Aged / Middle Aged / Single Photon Emission Computed Tomography / Public health systems and services research / Angina pectoris / Circulation / Laser Therapy / Coronary Circulation / Nervous System / Sympathetic Nervous System / Mechanism of action / Left Ventricle / Postoperative Period / Physical Endurance / Denervation / Clinical Sciences / Aged / Middle Aged / Single Photon Emission Computed Tomography / Public health systems and services research / Angina pectoris / Circulation / Laser Therapy / Coronary Circulation / Nervous System / Sympathetic Nervous System / Mechanism of action / Left Ventricle / Postoperative Period / Physical Endurance

Cardiac Sympathetic Denervation After Transmyocardial Laser Revascularization

Humans / PET imaging / Female / Male / Myocardial Revascularization / Denervation / Clinical Sciences / Aged / Middle Aged / Single Photon Emission Computed Tomography / Public health systems and services research / Angina pectoris / Circulation / Laser Therapy / Coronary Circulation / Nervous System / Sympathetic Nervous System / Mechanism of action / Left Ventricle / Postoperative Period / Physical Endurance / Denervation / Clinical Sciences / Aged / Middle Aged / Single Photon Emission Computed Tomography / Public health systems and services research / Angina pectoris / Circulation / Laser Therapy / Coronary Circulation / Nervous System / Sympathetic Nervous System / Mechanism of action / Left Ventricle / Postoperative Period / Physical Endurance

Methodological Issues in Comparative Effectiveness Research: Clinical Trials

Research Design / Mental Health / Clinical Trial / Rheumatoid Arthritis / Cardiovascular disease / Humans / Diabetes mellitus / Infectious Disease / United States / Patient Preference / Risk factors / Lessons Learned / Comparative Effectiveness Research / Risk Factors / Mechanism of action / Department of Veterans Affairs / Choice Behavior / Humans / Diabetes mellitus / Infectious Disease / United States / Patient Preference / Risk factors / Lessons Learned / Comparative Effectiveness Research / Risk Factors / Mechanism of action / Department of Veterans Affairs / Choice Behavior

Angiotensin converting enzyme inhibitor suppresses glomerular transforming growth factor β receptor expression in experimental diabetes in rats

Gene expression / Enalapril / Kidney / Blood Pressure / Renin Angiotensin Aldosterone System / Female / Animals / Hypertrophy / Diabetic Nephropathy / Clinical Sciences / Rats / Public health systems and services research / Western blot / Transforming Growth Factor Beta / Body Weight / Wistar Rats / Mechanism of action / Albuminuria / Streptozotocin / Growth Factor / Diabetic Rat / Angiotensin Converting Enzyme Inhibitors / ACE Inhibitor / Transforming Growth Factor / Female / Animals / Hypertrophy / Diabetic Nephropathy / Clinical Sciences / Rats / Public health systems and services research / Western blot / Transforming Growth Factor Beta / Body Weight / Wistar Rats / Mechanism of action / Albuminuria / Streptozotocin / Growth Factor / Diabetic Rat / Angiotensin Converting Enzyme Inhibitors / ACE Inhibitor / Transforming Growth Factor

Systemic Antibacterial Activity of Novel Synthetic Cyclic Peptides

Microbiology / Medical Microbiology / Treatment Outcome / Antibiotic Resistance / Gram Positive / Mice / Female / Animals / Antimicrobial activity / Staphylococcus aureus / Cyclic peptides / Antimicrobial Peptide / Steady state / Gram Positive Bacteria / Antibacterial activity / Mode of action / Anti-Bacterial Agents / Antimicrobial agents / Microbial Sensitivity Tests / Amino Acid Profile / Peritonitis / Mechanism of action / Membrane Potential / Structure activity Relationship / Food and Drug Administration / Thigh / Effective Dose / Vancomycin Resistant Enterococci (VRE) / Mice / Female / Animals / Antimicrobial activity / Staphylococcus aureus / Cyclic peptides / Antimicrobial Peptide / Steady state / Gram Positive Bacteria / Antibacterial activity / Mode of action / Anti-Bacterial Agents / Antimicrobial agents / Microbial Sensitivity Tests / Amino Acid Profile / Peritonitis / Mechanism of action / Membrane Potential / Structure activity Relationship / Food and Drug Administration / Thigh / Effective Dose / Vancomycin Resistant Enterococci (VRE)

Triptolide: a potential male contraceptive

Andrology / Female / Animals / Vehicle dynamic control / Male / tESTIS / Clinical Sciences / Rats / Analysis of Variance / Diterpenes / Body Weight / Mechanism of action / Sperm Motility / Sperm Count / Sertoli Cell / Luteinizing Hormone / Germ Cell / Follicle stimulating hormone / Radioimmunoassay / Seminiferous tubules / Organ Weight / tESTIS / Clinical Sciences / Rats / Analysis of Variance / Diterpenes / Body Weight / Mechanism of action / Sperm Motility / Sperm Count / Sertoli Cell / Luteinizing Hormone / Germ Cell / Follicle stimulating hormone / Radioimmunoassay / Seminiferous tubules / Organ Weight

Triptolide: A Potential Male Contraceptive

Andrology / Female / Animals / Vehicle dynamic control / Male / tESTIS / Clinical Sciences / Rats / Analysis of Variance / Diterpenes / Body Weight / Mechanism of action / Sperm Motility / Sperm Count / Sertoli Cell / Luteinizing Hormone / Germ Cell / Follicle stimulating hormone / Radioimmunoassay / Seminiferous tubules / Organ Weight / tESTIS / Clinical Sciences / Rats / Analysis of Variance / Diterpenes / Body Weight / Mechanism of action / Sperm Motility / Sperm Count / Sertoli Cell / Luteinizing Hormone / Germ Cell / Follicle stimulating hormone / Radioimmunoassay / Seminiferous tubules / Organ Weight
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