Mechanism of action

Smads oppose Hox transcriptional activities

Transcription Factors / DNA / Xenopus / Cercopithecus aethiops / Humans / Mice / Regulation of Gene Expression / Animals / Transcription Factor / Clinical Sciences / Potential Function / Mechanism of action / Protein Binding / Smad proteins / Biochemistry and cell biology / Mice / Regulation of Gene Expression / Animals / Transcription Factor / Clinical Sciences / Potential Function / Mechanism of action / Protein Binding / Smad proteins / Biochemistry and cell biology

Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo

Molecular endocrinology / Molecular / Enzymes / Insulin / Glucagon / Mice / cyclic AMP / Animals / Enzyme / Clinical Sciences / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Veterinary Sciences / Mechanism of action / Biological activity / Amino Acid Substitution Rates / Type 2 Diabetes Mellitus / Mice / cyclic AMP / Animals / Enzyme / Clinical Sciences / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Veterinary Sciences / Mechanism of action / Biological activity / Amino Acid Substitution Rates / Type 2 Diabetes Mellitus

Recomendaciones sobre ranelato de estroncio en el tratamiento de la osteoporosis

Older Women / Bone Mineral Density / Bone Formation / Mechanism of action / Bone Resorption

Recomendaciones sobre ranelato de estroncio en el tratamiento de la osteoporosis

Older Women / Bone Mineral Density / Bone Formation / Mechanism of action / Bone Resorption

Ultra-Low-Dose Opioid Antagonists Enhance Opioid Analgesia and Reduce Tolerance

Low Dose / Neuropathic pain / Mu Opioid Receptor / Clinical Study / Controlled Clinical Trial / Mechanism of action

Synthetic analogues of antimicrobial peptides from the venom of the Central Asian spider Lachesana tarabaevi

Spiders / Escherichia coli / Animals / Antimicrobial Peptide / Anti-Bacterial Agents / Antimicrobial Cationic Peptides / Bacillus subtilis / Amino Acid Profile / Mechanism of action / Biological activity / Amino Acid Sequence / Structure activity Relationship / Erythrocytes / Hemolysis / Bilayer Lipid Membrane / Disulfide bond / Antimicrobial Cationic Peptides / Bacillus subtilis / Amino Acid Profile / Mechanism of action / Biological activity / Amino Acid Sequence / Structure activity Relationship / Erythrocytes / Hemolysis / Bilayer Lipid Membrane / Disulfide bond

Boronic acids—A novel class of bacterial mutagen

Environmental Biotechnology / Humans / Mutation / Escherichia coli / Animals / Salmonella Typhimurium / Boronic Acids / Biotransformation / Mechanism of action / Mutagens / Salmonella Typhimurium / Boronic Acids / Biotransformation / Mechanism of action / Mutagens

Los β-agonistas adrenérgicos como modificadores metabólicos y su efecto en la producción, calidad e inocuidad de la carne de bovinos y ovinos: una revisión

Public Health / Animal Nutrition / Animal Production / Meat quality / Beef Cattle / Product Quality / Mechanism of action / Chemical Composition / Chemical Structure / Product Quality / Mechanism of action / Chemical Composition / Chemical Structure

Cellular resistance to anthracyclines

Genetics / DNA repair / Cell line / Humans / Multidrug Resistance / Drug Resistance / Glutathione / P-glycoprotein / Detoxification / Enzyme / Neoplasms / Chromosome segregation / Clinical Study / Mechanism of action / Plasma Membrane / Anticancer Drug / Drug Resistance / Glutathione / P-glycoprotein / Detoxification / Enzyme / Neoplasms / Chromosome segregation / Clinical Study / Mechanism of action / Plasma Membrane / Anticancer Drug

Bisphosphonates Are Incorporated into Adenine Nucleotides by Human Aminoacyl-tRNA Synthetase Enzymes

Cell line / Biochemical / Enzyme / Mechanism of action / aminoacyl-tRNA synthetase / Bone Resorption / Nucleotides / Biochemistry and cell biology / Bone Resorption / Nucleotides / Biochemistry and cell biology

Statistical Model To Evaluate In Vivo Activities of Antimalarial Drugs in a Plasmodium cynomolgi-Macaque Model for Plasmodium vivax Malaria

Microbiology / Medical Microbiology / Drug development / Prodrugs / Mixed Effects Models / Female / Animals / Drug Resistance / Male / Animal Model / South America / Animal Experimentation / Antimalarials / Rhesus macaques / Antimicrobial agents / Macaca Mulatta / Sub Saharan Africa / Statistical Model / Mechanism of action / Host Range / Plasmodium Vivax / Treatment Effect / Female / Animals / Drug Resistance / Male / Animal Model / South America / Animal Experimentation / Antimalarials / Rhesus macaques / Antimicrobial agents / Macaca Mulatta / Sub Saharan Africa / Statistical Model / Mechanism of action / Host Range / Plasmodium Vivax / Treatment Effect

Angiotensin converting enzyme inhibitor suppresses glomerular transforming growth factor β receptor expression in experimental diabetes in rats

Gene expression / Enalapril / Kidney / Blood Pressure / Renin Angiotensin Aldosterone System / Female / Animals / Hypertrophy / Diabetic Nephropathy / Clinical Sciences / Rats / Public health systems and services research / Western blot / Transforming Growth Factor Beta / Body Weight / Wistar Rats / Mechanism of action / Albuminuria / Streptozotocin / Growth Factor / Diabetic Rat / Angiotensin Converting Enzyme Inhibitors / ACE Inhibitor / Female / Animals / Hypertrophy / Diabetic Nephropathy / Clinical Sciences / Rats / Public health systems and services research / Western blot / Transforming Growth Factor Beta / Body Weight / Wistar Rats / Mechanism of action / Albuminuria / Streptozotocin / Growth Factor / Diabetic Rat / Angiotensin Converting Enzyme Inhibitors / ACE Inhibitor

Marine endoperoxides as antimalarial lead compounds

Organic Chemistry / Plant Biology / Mechanism of action

Ultrafine Airborne Particles Cause Increases in Protooncogene Expression and Proliferation in Alveolar Epithelial Cells

Flow Cytometry / Apoptosis / Gene expression / Cell Division / Lung Cancer / Mice / Animals / Particles / Steady state / Epithelial cells / Particulate Matter / Mechanism of action / Carbon Black / Cell Proliferation / Biological activity / Air Pollutants / Death Domain / Mice / Animals / Particles / Steady state / Epithelial cells / Particulate Matter / Mechanism of action / Carbon Black / Cell Proliferation / Biological activity / Air Pollutants / Death Domain

In Vitro and In Vivo Properties of Ellagic Acid in Malaria Treatment

Microbiology / Medical Microbiology / Plasmodium / Infectious Disease / Mice / Female / Animals / Antioxidant Activity / ATOVAQUONE / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Combination drug therapy / Plant production / Molecular weight / Mechanism of action / Chloroquine / Active Ingredient / Erythrocytes / Effective Dose / Mefloquine / Molecular Structure / Female / Animals / Antioxidant Activity / ATOVAQUONE / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Combination drug therapy / Plant production / Molecular weight / Mechanism of action / Chloroquine / Active Ingredient / Erythrocytes / Effective Dose / Mefloquine / Molecular Structure

A lesson in efficient killing from two-component lantibiotics

Molecular Microbiology / Biological Sciences / Bacteriocins / Sulfides / Anti-Bacterial Agents / Nisin / Alanine / Mechanism of action / Cell Wall / Nisin / Alanine / Mechanism of action / Cell Wall

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