L-asparaginase

An Inhibitor of Human Asparagine Synthetase Suppresses Proliferation of an L-Asparaginase-Resistant Leukemia Cell Line

Organic Chemistry / Enzyme Inhibitors / Cell line / Humans / Drug Resistance / L-asparaginase / Tight Binding / Cell Proliferation / Chemistry Biology / Antineoplastic Agents / Biochemistry and cell biology / Molecular Structure / Fghfgh / L-asparaginase / Tight Binding / Cell Proliferation / Chemistry Biology / Antineoplastic Agents / Biochemistry and cell biology / Molecular Structure / Fghfgh

Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth

Apoptosis / Gene Silencing / Signal Transduction / Dexamethasone / Humans / Child / Mice / Animals / Monoclonal Antibodies / L-asparaginase / Antineoplastic Agents / Molecular Targeted Therapy / Child / Mice / Animals / Monoclonal Antibodies / L-asparaginase / Antineoplastic Agents / Molecular Targeted Therapy

L-asparaginase as a critical component to combat Acute Lymphoblastic Leukaemia (ALL)_ a novel approach to target ALL

Leukemia / E. coli / L-asparaginase

Acute Lymphoblastic Leukemia in a Developing Country: Preliminary Results of a Nonrandomized Clinical Trial in El Salvador

Clinical Trial / Risk / Treatment / Developing Countries / Survival Analysis / International Cooperation / El Salvador / Adolescent / Humans / Child / Developing Country / United States / Female / Male / Infant / Pediatric / Risk factors / Newborn Infant / L-asparaginase / Time Factors / Methotrexate / Risk Factors / Pediatric Hematology Oncology / Acute Lymphoblastic Leukemia / Nino / International Cooperation / El Salvador / Adolescent / Humans / Child / Developing Country / United States / Female / Male / Infant / Pediatric / Risk factors / Newborn Infant / L-asparaginase / Time Factors / Methotrexate / Risk Factors / Pediatric Hematology Oncology / Acute Lymphoblastic Leukemia / Nino

Glutaminase-free asparaginase fromvibrio succinogenes: An antilymphoma enzyme lacking hepatotoxicity

Cancer / Lipids / Liver / Escherichia coli / Mice / Animals / Enzyme / L-asparaginase / Vibrio / Species Specificity / Animals / Enzyme / L-asparaginase / Vibrio / Species Specificity

Immunological and pharmacological characterization of poly-DL-alanyl-modified Erwinia carotovora L-asparaginase

Kinetics / Cancer / Humans / Mice / DBA / Animals / Peptides / Allergens / Immunoglobulin E / Enzyme / L-asparaginase / Rhesus Monkey / Macaca Mulatta / Erwinia / Whole Body / immunoglobulin G / Animals / Peptides / Allergens / Immunoglobulin E / Enzyme / L-asparaginase / Rhesus Monkey / Macaca Mulatta / Erwinia / Whole Body / immunoglobulin G

Immunological and pharmacological characterization of poly-DL-alanyl-modified Erwinia carotovora L-asparaginase

Kinetics / Cancer / Humans / Mice / Animals / Peptides / Allergens / Immunoglobulin E / Enzyme / L-asparaginase / Macaca Mulatta / Erwinia / immunoglobulin G / Peptides / Allergens / Immunoglobulin E / Enzyme / L-asparaginase / Macaca Mulatta / Erwinia / immunoglobulin G

Production of l-asparaginase in Enterobacter aerogenes expressing Vitreoscilla hemoglobin for efficient oxygen uptake

Production / Gene expression / Multidisciplinary / Glucose / Bacteria / Oxygen Uptake / Ammonia / Enzyme / Applied Microbiology and Biotechnology / Molecular cloning / Enterobacter aerogenes / L-asparaginase / Enzyme activity / Recombinant Proteins / Hydrogen-Ion Concentration / Oxygen Consumption / Oxidation-Reduction / Hemoglobins / Oxygen Uptake / Ammonia / Enzyme / Applied Microbiology and Biotechnology / Molecular cloning / Enterobacter aerogenes / L-asparaginase / Enzyme activity / Recombinant Proteins / Hydrogen-Ion Concentration / Oxygen Consumption / Oxidation-Reduction / Hemoglobins

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