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Compartmentalized phosphodiesterase-2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

Calcium / Signal Transduction / Mice / cyclic AMP / Nitric oxide / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol

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Mutagenesis of important amino acid reveals unconventional homologous internalization of β1-adrenergic receptor

Life Sciences / Western blotting / Internalization / Cell line / Humans / Mutation / cyclic AMP / D-Aspartic Acid / Lysine / Radioligand Assay / Amino Acid Profile / Transfection / Propranolol / Site-directed Mutagenesis / Ligands / Biochemistry and cell biology / Isoproterenol / Cell Membrane / Mutation / cyclic AMP / D-Aspartic Acid / Lysine / Radioligand Assay / Amino Acid Profile / Transfection / Propranolol / Site-directed Mutagenesis / Ligands / Biochemistry and cell biology / Isoproterenol / Cell Membrane

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AKT participates in endothelial dysfunction in hypertension

Signal Transduction / Humans / Hypertension / Insulin / Endothelial Cells / Doppler Ultrasound / Nitric oxide / Animals / Vascular endothelium / Acetylcholine / Gene Selection / Endothelial dysfunction / Clinical Sciences / Rats / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Blood Flow / Circulation / Primary Culture / Spontaneously Hypertensive Rats / Aorta / Vasodilation / Spontaneously Hypertensive Rat / Protein Transport / Gene Transfer / Isoproterenol / Cell Membrane / Doppler Ultrasound / Nitric oxide / Animals / Vascular endothelium / Acetylcholine / Gene Selection / Endothelial dysfunction / Clinical Sciences / Rats / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Blood Flow / Circulation / Primary Culture / Spontaneously Hypertensive Rats / Aorta / Vasodilation / Spontaneously Hypertensive Rat / Protein Transport / Gene Transfer / Isoproterenol / Cell Membrane

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Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial KATP channel and potential pERK 1/2 activation

Mitochondria / Apoptosis / Humans / Human right / Cytochrome C / Mitogen Activated Protein Kinase / Caspase / European / Hydrazones / Oxygen / Myocardium / Western blot / Muscle contraction / Potassium Channels / Mechanism of action / Isoproterenol / Mitogen Activated Protein Kinase / Caspase / European / Hydrazones / Oxygen / Myocardium / Western blot / Muscle contraction / Potassium Channels / Mechanism of action / Isoproterenol

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AKT Participates in Endothelial Dysfunction in Hypertension

Signal Transduction / Humans / Hypertension / Insulin / Endothelial Cells / Doppler Ultrasound / Nitric oxide / Animals / Vascular endothelium / Acetylcholine / Gene Selection / Endothelial dysfunction / Clinical Sciences / Rats / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Blood Flow / Circulation / Primary Culture / Spontaneously Hypertensive Rats / Aorta / Vasodilation / Spontaneously Hypertensive Rat / Protein Transport / Gene Transfer / Isoproterenol / Doppler Ultrasound / Nitric oxide / Animals / Vascular endothelium / Acetylcholine / Gene Selection / Endothelial dysfunction / Clinical Sciences / Rats / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Blood Flow / Circulation / Primary Culture / Spontaneously Hypertensive Rats / Aorta / Vasodilation / Spontaneously Hypertensive Rat / Protein Transport / Gene Transfer / Isoproterenol

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Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial KATP channel and potential pERK 1/2 activation

Mitochondria / Apoptosis / Humans / Human right / Cytochrome C / Mitogen Activated Protein Kinase / Caspase / European / Hydrazones / Oxygen / Myocardium / Western blot / Muscle contraction / Potassium Channels / Mechanism of action / Isoproterenol / Mitogen Activated Protein Kinase / Caspase / European / Hydrazones / Oxygen / Myocardium / Western blot / Muscle contraction / Potassium Channels / Mechanism of action / Isoproterenol

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integrales en linea

Probability / Blood Glucose / Hemodynamics / Animals / Male / Heart rate / Clinical Sciences / Rats / Body Weight / Wistar Rats / Cardiomyopathies / Streptozotocin / Diastolic Dysfunction/CHF / Reference Values / Diabetic Rat / Cardiac failure / Time Course / Isoproterenol / Heart rate / Clinical Sciences / Rats / Body Weight / Wistar Rats / Cardiomyopathies / Streptozotocin / Diastolic Dysfunction/CHF / Reference Values / Diabetic Rat / Cardiac failure / Time Course / Isoproterenol

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Mutagenesis of important amino acid reveals unconventional homologous internalization of β1-adrenergic receptor

Life Sciences / Western blotting / Cell line / Humans / Mutation / cyclic AMP / D-Aspartic Acid / Lysine / Radioligand Assay / Amino Acid Profile / Transfection / Propranolol / Site-directed Mutagenesis / Ligands / Biochemistry and cell biology / Isoproterenol / cyclic AMP / D-Aspartic Acid / Lysine / Radioligand Assay / Amino Acid Profile / Transfection / Propranolol / Site-directed Mutagenesis / Ligands / Biochemistry and cell biology / Isoproterenol

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A temporal-specific and transient cAMP increase characterizes odorant classical conditioning

Learning & Memory / Learning / Biological Sciences / Classical Conditioning / cyclic AMP / Female / Animals / Male / Phosphodiesterase Inhibitors / Odors / Rats / Time Factors / Olfactory Bulb / Isoproterenol / Female / Animals / Male / Phosphodiesterase Inhibitors / Odors / Rats / Time Factors / Olfactory Bulb / Isoproterenol

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Compartmentalized Phosphodiesterase-2 Activity Blunts  -Adrenergic Cardiac Inotropy via an NO/cGMP-Dependent Pathway

Calcium / Signal Transduction / Mice / cyclic AMP / Nitric oxide / Animals / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Circulation / Adenine / cyclic GMP / Isoproterenol / Animals / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Circulation / Adenine / cyclic GMP / Isoproterenol

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Compartmentalized Phosphodiesterase-2 Activity Blunts  -Adrenergic Cardiac Inotropy via an NO/cGMP-Dependent Pathway

Calcium / Signal Transduction / Mice / cyclic AMP / Nitric oxide / Animals / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Circulation / Adenine / cyclic GMP / Isoproterenol / Animals / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Circulation / Adenine / cyclic GMP / Isoproterenol

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Mutagenesis of important amino acid reveals unconventional homologous internalization of β1-adrenergic receptor

Life Sciences / Western blotting / Cell line / Humans / Mutation / cyclic AMP / D-Aspartic Acid / Lysine / Radioligand Assay / Amino Acid Profile / Transfection / Propranolol / Ligands / Biochemistry and cell biology / Isoproterenol / cyclic AMP / D-Aspartic Acid / Lysine / Radioligand Assay / Amino Acid Profile / Transfection / Propranolol / Ligands / Biochemistry and cell biology / Isoproterenol

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Comparison of withdrawal phenomena after propranolol, metoprolol, and pindolol

Humans / Hypertension / Blood Pressure / Heart rate / Aged / Middle Aged / Adult / Public health systems and services research / Time Factors / Propranolol / Isoproterenol / Middle Aged / Adult / Public health systems and services research / Time Factors / Propranolol / Isoproterenol

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Adipocyte beta-adrenoceptor sensitivity influences plasma lipid levels

Lipids / Adipose tissue / Humans / Fasting / Smoking / Female / Male / Regression Analysis / Triglycerides / Clinical Sciences / Glycerol / Adult / Isoproterenol / Female / Male / Regression Analysis / Triglycerides / Clinical Sciences / Glycerol / Adult / Isoproterenol

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Compartmentalized Phosphodiesterase-2 Activity Blunts  -Adrenergic Cardiac Inotropy via an NO/cGMP-Dependent Pathway

Calcium / Signal Transduction / Mice / cyclic AMP / Nitric oxide / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol

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Impact of AT2 Receptor Deficiency on Postnatal Cardiovascular Development

Engineering / Physics / Chemistry / Biology / Calcium / Medicine / Gene expression / Multidisciplinary / Signal Transduction / Mice / Blood Pressure / Animals / Heart / PLoS one / Myocardium / Time Factors / Body Weight / Angiotensin II / Isoproterenol / Atrial Natriuretic Factor / Immunoblotting / Medicine / Gene expression / Multidisciplinary / Signal Transduction / Mice / Blood Pressure / Animals / Heart / PLoS one / Myocardium / Time Factors / Body Weight / Angiotensin II / Isoproterenol / Atrial Natriuretic Factor / Immunoblotting

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