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Isoenzymes
Isoenzymes
Plasma Membrane Ca<sup>2+</sup>-ATPase Isoform Expression in Human Cataractous Lenses Compared to Age-Matched Clear Lenses
Aging / Calcium / Ophthalmic / Western blotting / Humans / Female / Male / Cataract / Real Time / Aged / Optometry and Ophthalmology / Adult / Isoenzymes / Western blot / Lens / Plasma Membrane / Intracellular Calcium / Female / Male / Cataract / Real Time / Aged / Optometry and Ophthalmology / Adult / Isoenzymes / Western blot / Lens / Plasma Membrane / Intracellular Calcium
Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension
Enzyme Inhibitors / Pulmonary Hypertension / Humans / Anoxia / Collagen / Mice / Female / Animals / Male / Young Adult / Clinical Sciences / Middle Aged / Elastin / Rats / Adult / Isoenzymes / Human Fibroblasts / Case Control Studies / Pulmonary Artery / Mice / Female / Animals / Male / Young Adult / Clinical Sciences / Middle Aged / Elastin / Rats / Adult / Isoenzymes / Human Fibroblasts / Case Control Studies / Pulmonary Artery
Plasma Membrane Ca<sup>2+</sup>-ATPase Isoform Expression in Human Cataractous Lenses Compared to Age-Matched Clear Lenses
Aging / Calcium / Ophthalmic / Western blotting / Humans / Female / Male / Cataract / Real Time / Aged / Optometry and Ophthalmology / Adult / Isoenzymes / Western blot / Lens / Plasma Membrane / Intracellular Calcium / Female / Male / Cataract / Real Time / Aged / Optometry and Ophthalmology / Adult / Isoenzymes / Western blot / Lens / Plasma Membrane / Intracellular Calcium
A novel disulphide switch mechanism in Ero1α balances ER oxidation in human cells
Biological Sciences / Cell line / Humans / Animals / Oxidoreductases / Glutathione / Endoplasmic Reticulum / Homeostasis / Isoenzymes / Cysteine / Oxidation-Reduction / Glutathione / Endoplasmic Reticulum / Homeostasis / Isoenzymes / Cysteine / Oxidation-Reduction
Adenoviral expression of protein-L-isoaspartyl methyltransferase (PIMT) partially attenuates the biochemical changes in PIMT-deficient mice
Neuroscience / Psychology / Epilepsy / Immunohistochemistry / Western blotting / Hippocampus / Brain / Mice / Animals / Neurons / Isoenzymes / Human Fibroblasts / Recombinant Proteins / Neurosciences / Hippocampus / Brain / Mice / Animals / Neurons / Isoenzymes / Human Fibroblasts / Recombinant Proteins / Neurosciences
Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites
Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting
Myristoyl CoA: protein N-myristoyltransferase: an essential enzyme and potential drug target in kinetoplastid parasites
Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting
Lysyl Oxidase (Lox) Gene Deficiency Affects Osteoblastic Phenotype
Biomedical Engineering / Structural Integrity / Apoptosis / Gene Silencing / DNA / Cell Differentiation / Mice / Animals / Skull / Osteopontin / Phenotype / Calcified tissue / Clinical Sciences / mRna expression levels / Isoenzymes / Osteoblasts / Biochemistry and cell biology / Down-Regulation / lysyl oxidase / Dna Synthesis / DNA fragmentation / Type I Collagen / Cell Differentiation / Mice / Animals / Skull / Osteopontin / Phenotype / Calcified tissue / Clinical Sciences / mRna expression levels / Isoenzymes / Osteoblasts / Biochemistry and cell biology / Down-Regulation / lysyl oxidase / Dna Synthesis / DNA fragmentation / Type I Collagen
Cyclooxygenase-2 expression in endometrial carcinoma
Cancer / Survival Analysis / Membrane Proteins / Immunohistochemistry / Humans / Female / Aged / Middle Aged / Carcinoma / Adult / Isoenzymes / Endometrial carcinoma / Female / Aged / Middle Aged / Carcinoma / Adult / Isoenzymes / Endometrial carcinoma
Cyclooxygenase-2 expression in endometrial carcinoma
Cancer / Survival Analysis / Membrane Proteins / Immunohistochemistry / Humans / Female / Aged / Middle Aged / Carcinoma / Adult / Isoenzymes / Endometrial carcinoma / Female / Aged / Middle Aged / Carcinoma / Adult / Isoenzymes / Endometrial carcinoma
Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †
Organic Chemistry / Medicinal Chemistry / Pharmacokinetics / Macromolecular X-Ray Crystallography / Cell line / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor
Postglacial genetic differentiation of reproductive ecotypes of kokanee Oncorhynchus nerka in Okanagan Lake, British Columbia
Reproduction / Ecology / Molecular Ecology / Biological Sciences / Mitochondrial DNA / Haplotypes / Female / Animals / Male / Salmon / Biological evolution / British Columbia / Phenotype / Genetic Differentiation / Isoenzymes / Fresh water / Genetic variation / Base Sequence / Haplotypes / Female / Animals / Male / Salmon / Biological evolution / British Columbia / Phenotype / Genetic Differentiation / Isoenzymes / Fresh water / Genetic variation / Base Sequence
Anti Transglutaminase Antibodies Cause Ataxia in Mice
Immunohistochemistry / Multidisciplinary / Antibodies / Brain / Humans / Autoimmune diseases / Celiac Disease / Gliadin / Mice / Female / Animals / Motor Coordination / Male / Phage display / PLoS one / Middle Aged / Rats / Adult / Isoenzymes / Ataxia / Blood Vessel / Motor Skills / Transglutaminases / Autoimmune diseases / Celiac Disease / Gliadin / Mice / Female / Animals / Motor Coordination / Male / Phage display / PLoS one / Middle Aged / Rats / Adult / Isoenzymes / Ataxia / Blood Vessel / Motor Skills / Transglutaminases
Sunflower (Helianthus annuus) fatty acid synthase complex: enoyl-[acyl carrier protein]-reductase genes
Kinetics / Plant Biology / Western blotting / Fatty acids / Substrate Specificity / Isoenzymes / Helianthus / Amino Acid Sequence / PLANT PROTEINS / Biosynthetic Pathways / Planta / Gene expression profiling / Isoenzymes / Helianthus / Amino Acid Sequence / PLANT PROTEINS / Biosynthetic Pathways / Planta / Gene expression profiling
Focal adhesion kinase promotes phospholipase C- 1 activity
Cell Adhesion / Multidisciplinary / Extracellular Matrix / Mice / Animals / Phosphorylation / T cells / Isoenzymes / Transfection / Glutathione Transferase / Recombinant Proteins / Enzymatic Activity / Plasma Membrane / Focal Adhesion Kinase / Cell Adhesion Molecules / Tyrosine Kinase / Tyrosine Phosphorylation / Phospholipase C / Phosphorylation / T cells / Isoenzymes / Transfection / Glutathione Transferase / Recombinant Proteins / Enzymatic Activity / Plasma Membrane / Focal Adhesion Kinase / Cell Adhesion Molecules / Tyrosine Kinase / Tyrosine Phosphorylation / Phospholipase C
Focal Adhesion Kinase Promotes Phospholipase C-gamma 1 Activity
Cell Adhesion / Multidisciplinary / Extracellular Matrix / Mice / Animals / Phosphorylation / T cells / Isoenzymes / Transfection / Glutathione Transferase / Recombinant Proteins / Enzymatic Activity / Plasma Membrane / Focal Adhesion Kinase / Cell Adhesion Molecules / Tyrosine Kinase / Tyrosine Phosphorylation / Phospholipase C / Phosphorylation / T cells / Isoenzymes / Transfection / Glutathione Transferase / Recombinant Proteins / Enzymatic Activity / Plasma Membrane / Focal Adhesion Kinase / Cell Adhesion Molecules / Tyrosine Kinase / Tyrosine Phosphorylation / Phospholipase C
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