Heme

Aryl aryl methyl thio arenes prevent multidrug-resistant malaria in mouse by promoting oxidative stress in parasites

Malaria / Oxidative Stress / Mice / EC / Animals / Drug Resistance / Male / Glutathione / Heme / Polycyclic aromatic hydrocarbons (PAHs) / Plasmodium falciparum / Antimalarials / Ec / Biochemistry and cell biology / Drug Resistance / Male / Glutathione / Heme / Polycyclic aromatic hydrocarbons (PAHs) / Plasmodium falciparum / Antimalarials / Ec / Biochemistry and cell biology

Glutathione‐S‐transferase activity in malarial parasites

Tropical Medicine / Tropical medicine (Health Sciences) / Humans / Mice / Animals / Drug Resistance / Glutathione / Heme / Public health systems and services research / Plasmodium falciparum / Antimalarials / Macaca Mulatta / Glutathione Transferase / Plasmodium yoelii / Chloroquine / Plasmodium Knowlesi / Plasmodium berghei / Drug Resistance / Glutathione / Heme / Public health systems and services research / Plasmodium falciparum / Antimalarials / Macaca Mulatta / Glutathione Transferase / Plasmodium yoelii / Chloroquine / Plasmodium Knowlesi / Plasmodium berghei

Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites

Humans / Mice / Female / Animals / Blood / Male / Heme / Phenotype / Clinical Sciences / Erythrocytes / Plasmodium berghei / Male / Heme / Phenotype / Clinical Sciences / Erythrocytes / Plasmodium berghei

Aminoacyl-tRNA Synthesis by Pre-Translational Amino Acid Modification

Genetics / Porphyrins / Phylogeny / Escherichia coli / Chlorophyll / Archaea / Heme / Amino Acids / Glutamine / Bacillus subtilis / RNA biology / Species Specificity / Asparagine / Archaea / Heme / Amino Acids / Glutamine / Bacillus subtilis / RNA biology / Species Specificity / Asparagine

Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites

Humans / Mice / Female / Animals / Blood / Male / Heme / Phenotype / Clinical Sciences / Erythrocytes / Plasmodium berghei / Male / Heme / Phenotype / Clinical Sciences / Erythrocytes / Plasmodium berghei

Applying malaria parasite’s heme detoxification system for screening potential antimalarial drugs

Analytical Chemistry / Malaria / Animals / Detoxification / Heme / Plasmodium falciparum / Antimalarials / Analytical Biochemistry / Biochemistry and cell biology / Plasmodium falciparum / Antimalarials / Analytical Biochemistry / Biochemistry and cell biology

Giardia lamblia encodes a functional flavohemoglobin

Protein Structure and Function / Nitric oxide / Mitochondrial Respiratory Chain / Heme / NADPH oxidase / Single Cell / Amino Acid Sequence / Genetic Code / Small Intestine / Biochemistry and cell biology / Functional Properties / Single Cell / Amino Acid Sequence / Genetic Code / Small Intestine / Biochemistry and cell biology / Functional Properties

A proximal tryptophan in NO synthase controls activity by a novel mechanism

Inorganic Chemistry / Kinetics / Cytochrome C / Spectrophotometry / Tryptophan / Heme / Enzyme / Steady state / Hydrogen Bond / Hydrogen Bonding / Nitric Oxide Synthase / Cysteine / Molecular Conformation / Protein Conformation / Inorganic Biochemistry / Amino Acid Substitution Rates / Recombinant Proteins / Site-directed Mutagenesis / Binding affinity / Heme / Enzyme / Steady state / Hydrogen Bond / Hydrogen Bonding / Nitric Oxide Synthase / Cysteine / Molecular Conformation / Protein Conformation / Inorganic Biochemistry / Amino Acid Substitution Rates / Recombinant Proteins / Site-directed Mutagenesis / Binding affinity

Trehalose Effect on Low Temperature Protein Dynamics: Fluctuation and Relaxation Phenomena

Biochemistry / Kinetics / Protein Dynamics / Biophysical Chemistry / Biological Sciences / Diffusion / Power Law / Physical sciences / Temperature / Trehalose / Heme / CHEMICAL SCIENCES / Glycerol / Time Factors / Low Temperature / Protein Conformation / Anomalous Diffusion / Hydrogen-Ion Concentration / Normal Distribution / Diffusion / Power Law / Physical sciences / Temperature / Trehalose / Heme / CHEMICAL SCIENCES / Glycerol / Time Factors / Low Temperature / Protein Conformation / Anomalous Diffusion / Hydrogen-Ion Concentration / Normal Distribution

Myeloperoxidase enhances nitric oxide catabolism during myocardial ischemia and reperfusion

Free Radicals / Immunohistochemistry / Free Radical / Peroxidase / Humans / Nitric oxide / Female / Animals / Male / Animal Model / Acetylcholine / Acute Myocardial Infarction / Endothelial dysfunction / Heme / Hydrogen Peroxide / Aged / Middle Aged / Neutrophils / Peripheral Vascular Disease / Myocardial Infarction / Myocardium / Time Factors / Rabbits / Coronary Artery Disease / Reperfusion injury / Ischemia–reperfusion / Enzyme Linked Immunosorbent Assay / Myeloperoxidase / Biochemistry and cell biology / Case Control Studies / Nitric oxide / Female / Animals / Male / Animal Model / Acetylcholine / Acute Myocardial Infarction / Endothelial dysfunction / Heme / Hydrogen Peroxide / Aged / Middle Aged / Neutrophils / Peripheral Vascular Disease / Myocardial Infarction / Myocardium / Time Factors / Rabbits / Coronary Artery Disease / Reperfusion injury / Ischemia–reperfusion / Enzyme Linked Immunosorbent Assay / Myeloperoxidase / Biochemistry and cell biology / Case Control Studies

Iron-deficiency anaemia enhances red blood cell oxidative stress

Fluorescence / Fluorescence Microscopy / Oxidative Stress / Free Radical / Biological Sciences / Mice / Animals / Male / Iron / Heme / CHEMICAL SCIENCES / Oxygen / Body Weight / Red blood cell / Iron Deficiency Anaemia / Erythrocytes / Iron Deficiency Anemia / Hematocrit / Hemoglobins / Methemoglobin / Mice / Animals / Male / Iron / Heme / CHEMICAL SCIENCES / Oxygen / Body Weight / Red blood cell / Iron Deficiency Anaemia / Erythrocytes / Iron Deficiency Anemia / Hematocrit / Hemoglobins / Methemoglobin

Imidazolyl Carboxylic Acids As Mechanistic Probes of Flavocytochrome P-450 BM3 †

Biochemistry / Catalysis / Kinetics / Enzyme Inhibitors / Fatty acids / Circular Dichroism / Heme / Substrate Specificity / Imidazoles / Arachidonic Acid / Biochemistry and cell biology / Circular Dichroism / Heme / Substrate Specificity / Imidazoles / Arachidonic Acid / Biochemistry and cell biology

Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism

Neurochemistry / Oxidative Stress / Mitochondria / Confocal Microscopy / Energy Metabolism / Brain / Generation / Copper / Nitric oxide / Animals / Astrocyte / Feedback / Mitochondrial Respiratory Chain / Electron Transport / Astrocytes / Cytochrome oxidase / Heme / Rats / NAD / Brain Chemistry / Lactic Acid / Oxygen Consumption / Neurosciences / Superoxides / Adenosine Triphosphate / Nitric oxide donors / Brain / Generation / Copper / Nitric oxide / Animals / Astrocyte / Feedback / Mitochondrial Respiratory Chain / Electron Transport / Astrocytes / Cytochrome oxidase / Heme / Rats / NAD / Brain Chemistry / Lactic Acid / Oxygen Consumption / Neurosciences / Superoxides / Adenosine Triphosphate / Nitric oxide donors

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