Haploinsufficiency

Restoration of Progranulin Expression Rescues Cortical Neuron Generation in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia

Neurogenesis / Gene expression / Transcriptome / Cell line / Cell Differentiation / Humans / Mutation / Neurons / Haploinsufficiency / Phenotype / Time Factors / Frontotemporal Dementia / Biological markers / Neural Stem Cells / Induced Pluripotent Stem Cells / Gene expression profiling / Humans / Mutation / Neurons / Haploinsufficiency / Phenotype / Time Factors / Frontotemporal Dementia / Biological markers / Neural Stem Cells / Induced Pluripotent Stem Cells / Gene expression profiling

Restoration of Progranulin Expression Rescues Cortical Neuron Generation in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia

Neurogenesis / Gene expression / Transcriptome / Cell line / Cell Differentiation / Humans / Mutation / Neurons / Haploinsufficiency / Phenotype / Time Factors / Frontotemporal Dementia / Biological markers / Neural Stem Cells / Induced Pluripotent Stem Cells / Gene expression profiling / Humans / Mutation / Neurons / Haploinsufficiency / Phenotype / Time Factors / Frontotemporal Dementia / Biological markers / Neural Stem Cells / Induced Pluripotent Stem Cells / Gene expression profiling

ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity

Mitochondria / Humans / Mice / Melanoma / Animals / Haploinsufficiency / Oxidative phosphorylation / Cell Proliferation / Skin Neoplasms / Haploinsufficiency / Oxidative phosphorylation / Cell Proliferation / Skin Neoplasms

ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity

Mitochondria / Humans / Mice / Melanoma / Animals / Haploinsufficiency / Oxidative phosphorylation / Cell Proliferation / Skin Neoplasms / Haploinsufficiency / Oxidative phosphorylation / Cell Proliferation / Skin Neoplasms

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