Glioblastoma

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Genomics / Adolescent / DNA repair / Gene expression / Multidisciplinary / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Genomics / Adolescent / DNA repair / Gene expression / Multidisciplinary / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms

An Extensive Invasive Intracranial Human Glioblastoma Xenograft Model

Cancer / Signal Transduction / Humans / Mice / Glioblastoma / Animals / Male / Astrocytes / Epidermal Growth Factor / Neoplasm Invasiveness / High / Cell Proliferation / Brain Neoplasms / Matrix Metalloproteinase / Animals / Male / Astrocytes / Epidermal Growth Factor / Neoplasm Invasiveness / High / Cell Proliferation / Brain Neoplasms / Matrix Metalloproteinase

Urokinase directly activates matrix metalloproteinases-9: A potential role in glioblastoma invasion

Humans / Glioblastoma / Biochemical / Gelatin / Spectrum / Neoplasm Invasiveness / Time Dependent / Molecular weight / Acute Phase Proteins / Brain Neoplasms / Biochemistry and cell biology / Matrix Metalloproteinase / Neoplasm Invasiveness / Time Dependent / Molecular weight / Acute Phase Proteins / Brain Neoplasms / Biochemistry and cell biology / Matrix Metalloproteinase

Glioblastoma induces vascular endothelial cells to express telomerase in vitro

Cancer / Telomerase / Brain Tumor / Humans / Glioblastoma / Tumor Angiogenesis / Astrocyte / Vascular endothelium / Endothelial cell / Protein Expression / Enzyme activity / Reverse Transcriptase / DNA binding proteins / Brain Neoplasms / Tumor Angiogenesis / Astrocyte / Vascular endothelium / Endothelial cell / Protein Expression / Enzyme activity / Reverse Transcriptase / DNA binding proteins / Brain Neoplasms

NFKBIA Deletion in Glioblastomas

Gene expression / Signal Transduction / Humans / Glioblastoma / NF-kappa B / New England / Prognosis / New England Journalof Medicine / New England / Prognosis / New England Journalof Medicine

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression

Signal Transduction / Humans / Glioblastoma / Alternative splicing / microRNAs / Disease Progression / Alternative Splicing / Clinical Investigation / Brain Neoplasms / Disease Progression / Alternative Splicing / Clinical Investigation / Brain Neoplasms

Intracranial gliomas in Ferrara, Italy, 1976 to 1991

Adolescent / Italy / Brain / Humans / Child / Glioma / Glioblastoma / Female / Male / Infant / Incidence / Clinical Sciences / Aged / Middle Aged / Adult / Astrocytoma / Cross Sectional Studies / Brain Neoplasms / Oligodendroglioma / Glioma / Glioblastoma / Female / Male / Infant / Incidence / Clinical Sciences / Aged / Middle Aged / Adult / Astrocytoma / Cross Sectional Studies / Brain Neoplasms / Oligodendroglioma

Antiangiogenic Therapy by Local Intracerebral Microinfusion Improves Treatment Efficiency and Survival in an Orthotopic Human Glioblastoma Model

Magnetic Resonance Imaging / Microcirculation / Treatment / Apoptosis / Cell Division / Caspases / Humans / Models / Glioma / Mice / Glioblastoma / Animals / Caspase / Time Factors / Cell Survival / Brain Neoplasms / Telencephalon / Caspases / Humans / Models / Glioma / Mice / Glioblastoma / Animals / Caspase / Time Factors / Cell Survival / Brain Neoplasms / Telencephalon

Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay

Oncology / Enzyme Inhibitors / Humans / Nitriles / Glioblastoma / Oxygen / Radiation Tolerance / Benzamides / Oxygen / Radiation Tolerance / Benzamides

Glioblastoma in multiple sclerosis: a case report

Multiple sclerosis / Data Analysis / Magnetic Resonance Imaging / Neuro-Oncology / Case Report / Humans / Glioblastoma / Male / Magnetic Resonance / Neuro / Differential Diagnosis / Transcription Factor / Middle Aged / Glioblastoma Multiforme / Neurosciences / Brain Neoplasms / Peripheral Blood Mononuclear Cells / Humans / Glioblastoma / Male / Magnetic Resonance / Neuro / Differential Diagnosis / Transcription Factor / Middle Aged / Glioblastoma Multiforme / Neurosciences / Brain Neoplasms / Peripheral Blood Mononuclear Cells

Hypoxia induces peroxisome proliferator-activated receptor α (PPARα) and lipid metabolism peroxisomal enzymes in human glioblastoma cells

Cellular / Humans / Glioblastoma / Lipid metabolism / Peroxisomes / Molecular and Cellular Biochemistry / Brain Neoplasms / Biochemistry and cell biology / Molecular and Cellular Biochemistry / Brain Neoplasms / Biochemistry and cell biology

Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity

Molecular Biology / Toxicology / Cancer stem cells / Humans / Glioblastoma / Animals / Akt / Cell Proliferation / Cell Survival / CM / Heterocyclic compounds / Down-Regulation / Animals / Akt / Cell Proliferation / Cell Survival / CM / Heterocyclic compounds / Down-Regulation

Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells

Gene Silencing / Molecular Mechanics / Western blotting / Cell line / Adenosine / Humans / Glioblastoma / Mitogen Activated Protein Kinase / Protein Expression / BIOCHEMICAL PHARMACOLOGY / Triazoles / Enzyme Linked Immunosorbent Assay / Vascular Endothelial Growth Factor / Humans / Glioblastoma / Mitogen Activated Protein Kinase / Protein Expression / BIOCHEMICAL PHARMACOLOGY / Triazoles / Enzyme Linked Immunosorbent Assay / Vascular Endothelial Growth Factor

A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma

Translational Medicine / Humans / Glioblastoma / Luminescence / Astrocytes / Doxorubicin / Stromal Cells / Reproducibility of Results / Somatic Cell Count / Cell Survival / Brain Neoplasms / Doxorubicin / Stromal Cells / Reproducibility of Results / Somatic Cell Count / Cell Survival / Brain Neoplasms

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Genomics / Adolescent / DNA repair / Gene expression / Multidisciplinary / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms

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