Glioblastoma

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Genomics / Cancer / Adolescent / DNA repair / Gene expression / Multidisciplinary / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms / Multidisciplinary / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms

Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay

Oncology / Enzyme Inhibitors / Humans / Nitriles / Glioblastoma / Oxygen / Radiation Tolerance / Benzamides / Oxygen / Radiation Tolerance / Benzamides

Astrocytes and Glioblastoma cells release exosomes carrying mtDNA

Psychology / Intercellular Communication / Transcription Factors / Mitochondrial DNA / Humans / Cerebral Cortex / Glioblastoma / Animals / Astrocyte / Exosomes / Gene Dosage / Astrocytes / Rats / Calcium Binding Proteins / Cell Cycle Proteins / DNA binding proteins / Neurosciences / Cerebral Cortex / Glioblastoma / Animals / Astrocyte / Exosomes / Gene Dosage / Astrocytes / Rats / Calcium Binding Proteins / Cell Cycle Proteins / DNA binding proteins / Neurosciences

Transdifferentiation of glioblastoma cells into vascular endothelial cells

Multidisciplinary / Humans / Endothelial Cells / Cell fusion / Mice / Glioblastoma / Animals / Glioblastoma / Animals

Array comparative genomic hybridization identifies novel potential therapeutic targets in cholangiocarcinoma

Genetics / Cancer / Survival Analysis / Immunohistochemistry / Treatment Outcome / Electrocardiography / DNA / Humans / Genetic Testing / Glioblastoma / Female / Nucleic acid hybridization / Renal cell Carcinoma / Male / Cluster Analysis / Long QT syndrome / Gene Dosage / Genes / Clinical Sciences / Aged / Middle Aged / Doxorubicin / Microarray Analysis / Adult / Cholangiocarcinoma / Retrospective Studies / Prognosis / Sudden Cardiac Death / Diffuse Large B-Cell Lymphoma / Reproducibility of Results / Individualized Medicine / DNA Copy Number / Cyclophosphamide / Molecular Targeted Therapy / Predictive value of tests / Brain Neoplasms / Comparative Genomic Hybridization / Array Comparative Genomic Hybridization / Gene expression profiling / Hematopoietic Stem Cell Transplantation / Electrocardiography / DNA / Humans / Genetic Testing / Glioblastoma / Female / Nucleic acid hybridization / Renal cell Carcinoma / Male / Cluster Analysis / Long QT syndrome / Gene Dosage / Genes / Clinical Sciences / Aged / Middle Aged / Doxorubicin / Microarray Analysis / Adult / Cholangiocarcinoma / Retrospective Studies / Prognosis / Sudden Cardiac Death / Diffuse Large B-Cell Lymphoma / Reproducibility of Results / Individualized Medicine / DNA Copy Number / Cyclophosphamide / Molecular Targeted Therapy / Predictive value of tests / Brain Neoplasms / Comparative Genomic Hybridization / Array Comparative Genomic Hybridization / Gene expression profiling / Hematopoietic Stem Cell Transplantation

Xenograft transplantation of human malignant astrocytoma cells into immunodeficient rats: an experimental model of glioblastoma

Humans / Glioblastoma / Female / Animals / Rats / Immunocompromised host / Astrocytoma / Clinics / Brain Neoplasms / Experimental Model / Immunocompromised host / Astrocytoma / Clinics / Brain Neoplasms / Experimental Model

Gamma interferon-mediated superinduction of B7-H1 in PTEN-deficient glioblastoma: a paradoxical mechanism of immune evasion

Cognitive Science / Enzyme Inhibitors / Apoptosis / Signal Transduction / Humans / Glioblastoma / Immune Evasion / T lymphocytes / Lymphocytes / Antineoplastic Agents / Neurosciences / Brain Neoplasms / Interferon gamma / Glioblastoma / Immune Evasion / T lymphocytes / Lymphocytes / Antineoplastic Agents / Neurosciences / Brain Neoplasms / Interferon gamma

[ 177 Lu]Bz-DTPA-EGF: Preclinical Characterization of a Potential Radionuclide Targeting Agent Against Glioma

Humans / Mice / Glioblastoma / Animals / Epidermal Growth Factor / Radiopharmaceuticals / Sensitivity and Specificity / Radioisotopes / Protein Binding / Chelating Agents / Radiopharmaceuticals / Sensitivity and Specificity / Radioisotopes / Protein Binding / Chelating Agents

Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice

Magnetic Resonance Imaging / Immunohistochemistry / Brain Tumor / Humans / Mice / Glioblastoma / Animals / Clinical / Clinical oncology / Kinase inhibitor / Antineoplastic Agents / Protein Kinase Inhibitors / Brain Edema / Brain Neoplasms / Vascular endothelial growth factor receptor / Quinazolines / Glioblastoma / Animals / Clinical / Clinical oncology / Kinase inhibitor / Antineoplastic Agents / Protein Kinase Inhibitors / Brain Edema / Brain Neoplasms / Vascular endothelial growth factor receptor / Quinazolines

Hyperintense signal in pyramidal tract neurons in postoperative brain tumor: wallerian degeneration or neoplastic dissemination?

Cognitive Science / Magnetic Resonance Imaging / Humans / Glioblastoma / Male / Differential Diagnosis / Clinical Sciences / Middle Aged / Brain Neoplasms / Differential Diagnosis / Clinical Sciences / Middle Aged / Brain Neoplasms

Dendrosomal curcumin nanoformulation downregulates pluripotency genes via miR-145 activation in U87MG glioblastoma cells

Cancer / Cell Cycle / Nanomedicine / Cancer Biology / Nanotechnology / Transcription Factors / Pharmaceutical Chemistry / Apoptosis / Caspases / miRNA / Humans / Glioblastoma / Curcumin / Cell Death / microRNAs / Nanocapsules / Drug Carriers / Drug Stability / Molecular Targeted Therapy / Down-Regulation / Transcription Factors / Pharmaceutical Chemistry / Apoptosis / Caspases / miRNA / Humans / Glioblastoma / Curcumin / Cell Death / microRNAs / Nanocapsules / Drug Carriers / Drug Stability / Molecular Targeted Therapy / Down-Regulation

ELTD1, a Potential New Biomarker for Gliomas

Neurosurgery / Computational Biology / Magnetic Resonance Imaging / Immunohistochemistry / Western blotting / Humans / G protein-coupled receptors / Glioblastoma / Female / Animals / Male / Clinical Sciences / Rats / Microarray Analysis / Adult / Neurosciences / Brain Neoplasms / Humans / G protein-coupled receptors / Glioblastoma / Female / Animals / Male / Clinical Sciences / Rats / Microarray Analysis / Adult / Neurosciences / Brain Neoplasms

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

Stem Cells / Cancer / Multidisciplinary / Nature / Neural stem cell / Cell Differentiation / Humans / Endothelial Cells / Mice / Glioblastoma / Animals / Vascular endothelium / Cancer Stem Cell / Endothelial cell / In vitro culture / Degeneration / Neural Stem Cells / Vascular Endothelial Growth Factor / Cell Differentiation / Humans / Endothelial Cells / Mice / Glioblastoma / Animals / Vascular endothelium / Cancer Stem Cell / Endothelial cell / In vitro culture / Degeneration / Neural Stem Cells / Vascular Endothelial Growth Factor

ELTD1, a Potential New Biomarker for Gliomas

Neurosurgery / Computational Biology / Magnetic Resonance Imaging / Immunohistochemistry / Western blotting / Humans / G protein-coupled receptors / Glioblastoma / Female / Animals / Male / Clinical Sciences / Rats / Microarray Analysis / Adult / Neurosciences / Brain Neoplasms / Humans / G protein-coupled receptors / Glioblastoma / Female / Animals / Male / Clinical Sciences / Rats / Microarray Analysis / Adult / Neurosciences / Brain Neoplasms

DNA ligase IV is a potential molecular target in ACNU sensitivity

DNA repair / Cell line / Humans / Mice / Glioblastoma / Animals / Antineoplastic Agents / Animals / Antineoplastic Agents

Local intracerebral delivery of endogenous inhibitors by osmotic minipumps effectively suppresses glioma growth in vivo

Cancer / Immunohistochemistry / Cell Division / Humans / Mice / Glioblastoma / Animals / Chemical Analysis / Cattle / Malignant Glioma / Side Effect / Biological activity / Amino Acid Sequence / Recombinant Proteins / Tumor Growth / Brain Neoplasms / Glioblastoma / Animals / Chemical Analysis / Cattle / Malignant Glioma / Side Effect / Biological activity / Amino Acid Sequence / Recombinant Proteins / Tumor Growth / Brain Neoplasms
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