Gene Therapy

An enhanced autogene-based dual-promoter cytoplasmic expression system yields increased gene expression

Gene Therapy / RNA polymerase / Gene expression / Biological Sciences / Cell line / Virus / Animals / Gene transfer techniques / Plasmids / VECTOR / Shell Half-Life / Gene Delivery / Cell nucleus / Transfection / Cytoplasm / High Efficiency / Gene Transfer / Gene Expression Regulation / Virus / Animals / Gene transfer techniques / Plasmids / VECTOR / Shell Half-Life / Gene Delivery / Cell nucleus / Transfection / Cytoplasm / High Efficiency / Gene Transfer / Gene Expression Regulation

Padlock oligonucleotides as a tool for labeling superhelical DNA

Electron Microscopy / Gene Therapy / Atomic Force Microscopy / Biological Sciences / DNA / Environmental Sciences / Triple Helix / Nucleic Acids / Plasmids / Streptavidin / Substrate Specificity / Base Sequence / Protein Binding / Nucleic Acid Conformation / Oligonucleotides / Biotinylation / single stranded DNA / DNA sequence / Environmental Sciences / Triple Helix / Nucleic Acids / Plasmids / Streptavidin / Substrate Specificity / Base Sequence / Protein Binding / Nucleic Acid Conformation / Oligonucleotides / Biotinylation / single stranded DNA / DNA sequence

Primary cellular immunodeficiencies

Genetics / Immunology / Gene Therapy / Treatment / Stem Cell / Primary / Genetic counseling / Humans / Cord Blood / Classification / T lymphocytes / Spectrum / Bone Marrow Transplantation / Prenatal Diagnosis / Life Span / DiGeorge Syndrome / Immunoglobulin / Severe combined immunodeficiency / Clinical Allergy and Immunology / Primary / Genetic counseling / Humans / Cord Blood / Classification / T lymphocytes / Spectrum / Bone Marrow Transplantation / Prenatal Diagnosis / Life Span / DiGeorge Syndrome / Immunoglobulin / Severe combined immunodeficiency / Clinical Allergy and Immunology

Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors

Gene Therapy / DNA damage / Apoptosis / Signal Transduction / Biological Sciences / Cell line / Humans / Cancer Therapy / Gene transfer techniques / Cell Death / Endoplasmic Reticulum / Lentivirus / Cancer Gene Therapy / Cisplatin / Tumor necrosis factor-alpha / Base Sequence / Resistance Genes Mechanism) / Golgi Apparatus / Cell Surface Markers / Cell line / Humans / Cancer Therapy / Gene transfer techniques / Cell Death / Endoplasmic Reticulum / Lentivirus / Cancer Gene Therapy / Cisplatin / Tumor necrosis factor-alpha / Base Sequence / Resistance Genes Mechanism) / Golgi Apparatus / Cell Surface Markers

Hemofilia: diagnóstico molecular y alternativas de tratamiento

Genetics / Colombia / Quality of life / Gene Therapy / Therapy / Prenatal Diagnosis / X chromosome / Molecular Diagnosis / Primary Prevention / Prenatal Diagnosis / X chromosome / Molecular Diagnosis / Primary Prevention

Hemofilia: diagnóstico molecular y alternativas de tratamiento

Genetics / Colombia / Quality of life / Gene Therapy / Therapy / Prenatal Diagnosis / X chromosome / Molecular Diagnosis / Primary Prevention / Prenatal Diagnosis / X chromosome / Molecular Diagnosis / Primary Prevention

Nuevos tratamientos de la enfermedad arterial periférica oclusiva no revascularizable: angiogenia terapéutica

Gene Therapy / Cell therapy / Endothelial cell / Medicina Clinica

Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency

Gene Therapy / Biological Sciences / DNA / Humans / Surface Charge / Structural Properties / Transfection / Polyethylenimine / Polyethyleneimine / Structural Properties / Transfection / Polyethylenimine / Polyethyleneimine

Infectious Delivery and Expression of a 135 kb Human FRDA Genomic DNA Locus Complements Friedreich\'s Ataxia Deficiency in Human Cells

Technology / Gene Therapy / Oxidative Stress / Biological Sciences / Molecular / Humans / Mice / Animals / Central Nervous System / Genomic DNA / Degeneration / Molecular weight / Cell Survival / High Efficiency / Molecular Targeted Therapy / Friedreich Ataxia / Iron binding proteins / fibroblasts / Humans / Mice / Animals / Central Nervous System / Genomic DNA / Degeneration / Molecular weight / Cell Survival / High Efficiency / Molecular Targeted Therapy / Friedreich Ataxia / Iron binding proteins / fibroblasts

Intratumoral 5-Fluorouracil Produced by Cytosine Deaminase/5-Fluorocytosine Gene Therapy Is Effective for Experimental Human Glioblastomas1

Clinical Trial / Kinetics / Cancer / Gene Therapy / Drug delivery / Prostate Cancer / Head and Neck / Cell line / Prodrugs / Humans / Escherichia coli / Mice / Glioblastoma / Animals / Multiple Linear Regression / Mouse Model / Malignant Glioma / Rat Model / Brain Neoplasms / Severe combined immunodeficiency / Gene Transfer / 5-FLUOROURACIL / Prostate Cancer / Head and Neck / Cell line / Prodrugs / Humans / Escherichia coli / Mice / Glioblastoma / Animals / Multiple Linear Regression / Mouse Model / Malignant Glioma / Rat Model / Brain Neoplasms / Severe combined immunodeficiency / Gene Transfer / 5-FLUOROURACIL

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