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Gene Therapy
Gene Therapy
Direct In Vivo Gene Transfer to Airway Epithelium Employing Adenovirus–Polylysine–DNA Complexes
Gene Therapy / Gene expression / DNA / Humans / Medical Biotechnology / Animals / Feasibility Studies / Sigmodontinae / Clinical Sciences / Rats / Epithelium / Trachea / Transfection / Primary Culture / Gene Transfer / Animals / Feasibility Studies / Sigmodontinae / Clinical Sciences / Rats / Epithelium / Trachea / Transfection / Primary Culture / Gene Transfer
Human Treg responses allow sustained recombinant adeno-associated virus– mediated transgene expression
Gene Therapy / Tregs / Adeno-associated virus
Transfection efficiency boost by designer multicomponent lipoplexes
Chemical Engineering / Clinical Trial / Gene Therapy / Small Angle X Ray Scattering / Biological Sciences / DNA / Cell line / Diffusion / Mice / Animals / Physical sciences / Liposomes / Structural Change / Gene Delivery / Transfection / Drug Carriers / Biochemistry and cell biology / DNA / Cell line / Diffusion / Mice / Animals / Physical sciences / Liposomes / Structural Change / Gene Delivery / Transfection / Drug Carriers / Biochemistry and cell biology
Recombinant Adeno-Associated Virus Serotype 9 Leads to Preferential Cardiac Transduction In Vivo
Genetics / Gene Therapy / Electrocardiography / Mice / Animals / Heart / Adeno-associated virus / Heart Disease / Clinical Sciences / Gene Delivery / Mouse Model / Skeletal Muscle / Circulation / Genetic Recombination / Gene Transfer / Serotyping / Heart / Adeno-associated virus / Heart Disease / Clinical Sciences / Gene Delivery / Mouse Model / Skeletal Muscle / Circulation / Genetic Recombination / Gene Transfer / Serotyping
175. A clinical trial in Japan of retroviral-mediated gene transfer to bone marrow CD34+ cells as a treatment of adenosine deaminase (ADA)-deficiency
Technology / Clinical Trial / Gene Therapy / Biological Sciences / Bone marrow / Enzyme / Adverse Event / Adverse Drug Reaction / Immune Reconstitution / Adenosine Deaminase / Molecular Targeted Therapy / Enzyme Replacement Therapy / Severe combined immunodeficiency / Gene Transfer / Enzyme / Adverse Event / Adverse Drug Reaction / Immune Reconstitution / Adenosine Deaminase / Molecular Targeted Therapy / Enzyme Replacement Therapy / Severe combined immunodeficiency / Gene Transfer
Accurate estimation of transduction efficiency necessitates a multiplex real-time PCR
Gene Therapy / Virology / Molecular virology / Horizontal Gene Transfer / Retroviruses / Transduction / GFP Chromophore Dynamics / Transduction / GFP Chromophore Dynamics
Prolonged liver-specific transgene expression by a non-primate lentiviral vector
Gene Therapy / Gene expression / Cats / Primates / Metabolic Bone Disease / Humans / Animals / Hepatocellular Carcinoma / Biochemical / Gene Delivery / Human immunodeficiency virus / Transfection / In Vitro Studies / Liver Disease / Transgene Expression / Plasmid DNA / Feline immunodeficiency virus / Biochemistry and cell biology / Transient Expression / Humans / Animals / Hepatocellular Carcinoma / Biochemical / Gene Delivery / Human immunodeficiency virus / Transfection / In Vitro Studies / Liver Disease / Transgene Expression / Plasmid DNA / Feline immunodeficiency virus / Biochemistry and cell biology / Transient Expression
Intramyocardial transplantation of fibroblasts expressing vascular endothelial growth factor attenuates cardiac dysfunction
Gene Therapy / Biological Sciences / Cell therapy / Fibrin / Animals / Male / Cell Transplantation / Rats / Myocardial Infarction / Growth Factor / Human Fibroblasts / Ischemia–reperfusion / Transgene Expression / Left Ventricle / Vascular Endothelial Growth Factor / Male / Cell Transplantation / Rats / Myocardial Infarction / Growth Factor / Human Fibroblasts / Ischemia–reperfusion / Transgene Expression / Left Ventricle / Vascular Endothelial Growth Factor
Gene transfection efficiency of tracheal epithelial cells by DC-Chol–DOPE/DNA complexes
Chemical Engineering / Electron Microscopy / Gene Therapy / Transmission Electron Microscopy / Fluorescent Dyes and Reagents / Confocal Microscopy / Biological Sciences / DNA / Cell line / Humans / Cholesterol / Cytomegalovirus / Physical sciences / Liposomes / Structure Analysis / Epithelial cells / Trachea / Confocal Laser Scanning Microscopy / Transfection / Bovine Serum Albumin / Organic Chemicals / Plasmid DNA / Biochemistry and cell biology / Gene Transfer / Confocal Microscopy / Biological Sciences / DNA / Cell line / Humans / Cholesterol / Cytomegalovirus / Physical sciences / Liposomes / Structure Analysis / Epithelial cells / Trachea / Confocal Laser Scanning Microscopy / Transfection / Bovine Serum Albumin / Organic Chemicals / Plasmid DNA / Biochemistry and cell biology / Gene Transfer
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences
Biology / Gene Therapy / Medicine / Protein Engineering / Biological Sciences / DNA / Environmental Sciences / Humans / Mutation / Nucleic Acids / Substrate Specificity / DNA binding / Gene Targeting / Genome sequence / Nucleotides / Dimerization / DNA / Environmental Sciences / Humans / Mutation / Nucleic Acids / Substrate Specificity / DNA binding / Gene Targeting / Genome sequence / Nucleotides / Dimerization
Gene transfection efficiency of tracheal epithelial cells by DC-Chol–DOPE/DNA complexes
Chemical Engineering / Electron Microscopy / Gene Therapy / Transmission Electron Microscopy / Fluorescent Dyes and Reagents / Confocal Microscopy / Biological Sciences / DNA / Cell line / Humans / Cholesterol / Cytomegalovirus / Physical sciences / Liposomes / Structure Analysis / Epithelial cells / Trachea / Confocal Laser Scanning Microscopy / Transfection / Bovine Serum Albumin / Organic Chemicals / Plasmid DNA / Biochemistry and cell biology / Gene Transfer / Confocal Microscopy / Biological Sciences / DNA / Cell line / Humans / Cholesterol / Cytomegalovirus / Physical sciences / Liposomes / Structure Analysis / Epithelial cells / Trachea / Confocal Laser Scanning Microscopy / Transfection / Bovine Serum Albumin / Organic Chemicals / Plasmid DNA / Biochemistry and cell biology / Gene Transfer
Intracisternal rSV40 administration provides effective pan-CNS transgene expression
Genetics / Gene Therapy / Immunohistochemistry / Oxidative Stress / Apoptosis / HIV / Biological Sciences / Female / Animals / Gene transfer techniques / Glutathione Peroxidase / Central Nervous System / Neurons / Superoxide Dismutase / Gene Delivery / Rats / Transgene Expression / Mannitol / Gene Transfer / Neuroprotective Agents / HIV / Biological Sciences / Female / Animals / Gene transfer techniques / Glutathione Peroxidase / Central Nervous System / Neurons / Superoxide Dismutase / Gene Delivery / Rats / Transgene Expression / Mannitol / Gene Transfer / Neuroprotective Agents
Gene transfection efficiency of tracheal epithelial cells by DC-Chol–DOPE/DNA complexes
Chemical Engineering / Electron Microscopy / Gene Therapy / Transmission Electron Microscopy / Fluorescent Dyes and Reagents / Confocal Microscopy / Biological Sciences / DNA / Cell line / Humans / Cholesterol / Cytomegalovirus / Physical sciences / Liposomes / Structure Analysis / Epithelial cells / Trachea / Confocal Laser Scanning Microscopy / Transfection / Bovine Serum Albumin / Organic Chemicals / Plasmid DNA / Biochemistry and cell biology / Gene Transfer / Confocal Microscopy / Biological Sciences / DNA / Cell line / Humans / Cholesterol / Cytomegalovirus / Physical sciences / Liposomes / Structure Analysis / Epithelial cells / Trachea / Confocal Laser Scanning Microscopy / Transfection / Bovine Serum Albumin / Organic Chemicals / Plasmid DNA / Biochemistry and cell biology / Gene Transfer
In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejection
Immune response / Nonparametric Statistics / Gene Therapy / Kidney transplantation / Immunohistochemistry / Gene Silencing / Biological Sciences / Antibodies / Renal transplantation / Animals / Male / Polymerase Chain Reaction / Rats / Kidney Transplant / Wistar Rats / Combination drug therapy / Graft Rejection / Sirolimus / Acute rejection / Gene Silencing / Biological Sciences / Antibodies / Renal transplantation / Animals / Male / Polymerase Chain Reaction / Rats / Kidney Transplant / Wistar Rats / Combination drug therapy / Graft Rejection / Sirolimus / Acute rejection
Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis
Electron Microscopy / Skeletal muscle biology / Gene Therapy / Immunohistochemistry / Confocal Microscopy / Brain / Female / Animals / Disease Severity / Electromyography / Synaptic Transmission / Fluorescent Antibody Technique / Rats / Myasthenia Gravis / Human Disease / Action Potentials / Individual Difference / Neuromuscular Junction / Radioimmunoassay / Brain / Female / Animals / Disease Severity / Electromyography / Synaptic Transmission / Fluorescent Antibody Technique / Rats / Myasthenia Gravis / Human Disease / Action Potentials / Individual Difference / Neuromuscular Junction / Radioimmunoassay
Class-, gene-, and group-specific HLA silencing by lentiviral shRNA delivery
Molecular Medicine / Gene Therapy / Regenerative Medicine / Gene Silencing / RNA interference / Cell line / Humans / Natural Killer cells / Lentivirus / T lymphocytes / B Lymphocytes / Immune Tolerance / Cell free System / NK Cell / In Vitro Transcription / Interferon gamma / Cell line / Humans / Natural Killer cells / Lentivirus / T lymphocytes / B Lymphocytes / Immune Tolerance / Cell free System / NK Cell / In Vitro Transcription / Interferon gamma
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