Fibrosis | DATOSPDF

Vimentin knockdown decreases corneal opacity

RNA / Wound Healing / Cornea / Confocal Microscopy / Western blotting / Biological Sciences / Mice / Female / Animals / Follow-up studies / Fibrosis / Plasmids / Corneal Opacity / Vimentin / Gene Expression Regulation / Corneal Keratocytes / Biological Sciences / Mice / Female / Animals / Follow-up studies / Fibrosis / Plasmids / Corneal Opacity / Vimentin / Gene Expression Regulation / Corneal Keratocytes

Download

H3 Relaxin Demonstrates Antifibrotic Properties via the RXFP1 Receptor

Biochemistry / Humans / Collagen / Mice / G protein-coupled receptors / Animals / Male / Fibrosis / Rats / Matrix Metalloproteinases / Transforming Growth Factor Beta / Human Fibroblasts / Heart Ventricles / Biochemistry and cell biology / Relaxin / Animals / Male / Fibrosis / Rats / Matrix Metalloproteinases / Transforming Growth Factor Beta / Human Fibroblasts / Heart Ventricles / Biochemistry and cell biology / Relaxin

Download

Serelaxin is a more efficacious antifibrotic than enalapril in an experimental model of heart disease

Treatment Outcome / Enalapril / Hypertension / Mice / Blood Pressure / Renin Angiotensin Aldosterone System / Animals / Male / Heart / Fibrosis / Clinical Sciences / Myocardium / Recombinant Proteins / Relaxin / Heart Diseases / Renin Angiotensin Aldosterone System / Animals / Male / Heart / Fibrosis / Clinical Sciences / Myocardium / Recombinant Proteins / Relaxin / Heart Diseases

Download

ALMS1-Deficient Fibroblasts Over-Express Extra-Cellular Matrix Components, Display Cell Cycle Delay and Are Resistant to Apoptosis

Genetics / DNA MICROARRAYS / Cell Cycle / Apoptosis / Multidisciplinary / Extracellular Matrix / Humans / Alstrom syndrome / Female / Male / Young Adult / Fibrosis / Proteins / PLoS one / Adult / Genetic Disorder / Cell Shape / ALMS / Gene Expression Analysis / Type 2 Diabetes Mellitus / Human Fibroblasts / Gene Expression Regulation / Gene expression profiling / Cell Size / Intracellular Transport / Extracellular Matrix / Humans / Alstrom syndrome / Female / Male / Young Adult / Fibrosis / Proteins / PLoS one / Adult / Genetic Disorder / Cell Shape / ALMS / Gene Expression Analysis / Type 2 Diabetes Mellitus / Human Fibroblasts / Gene Expression Regulation / Gene expression profiling / Cell Size / Intracellular Transport

Download

Tranilast, an orally active antiallergic compound, inhibits extracellular matrix production in human uterine leiomyoma and myometrial cells

Extracellular Matrix / Humans / Fertility and Sterility / Female / Fibrosis / Clinical Sciences / Middle Aged / Fibronectin / Adult / Public health systems and services research / Leiomyoma / Myometrium / Clinical Sciences / Middle Aged / Fibronectin / Adult / Public health systems and services research / Leiomyoma / Myometrium

Download

HMG-CoA reductase inhibition prior reperfusion improves reparative fibrosis post-myocardial infarction in a preclinical experimental model

Cardiology / Female / Animals / Fibrosis / Myocardial Infarction / Swine

Download

HMG-CoA reductase inhibition prior reperfusion improves reparative fibrosis post-myocardial infarction in a preclinical experimental model

Cardiology / Female / Animals / Fibrosis / Myocardial Infarction / Swine

Download

Dioscorea villosa (wild yam) induces chronic kidney injury via pro-fibrotic pathways

Kidney diseases / Cytokines / Immunohistochemistry / Rheumatoid Arthritis / Oxidative Stress / Macrophages / Western blotting / Liver / Chronic Disease / Animals / Male / Heme Oxygenase / Fibrosis / Transcription Factor / Renal Function / Plant extracts / Rats / Protein Expression / Food Sciences / Growth Factor / Human Fibroblasts / Food and Chemical Toxicology / Renal Fibrosis / Dioscorea / Macrophages / Western blotting / Liver / Chronic Disease / Animals / Male / Heme Oxygenase / Fibrosis / Transcription Factor / Renal Function / Plant extracts / Rats / Protein Expression / Food Sciences / Growth Factor / Human Fibroblasts / Food and Chemical Toxicology / Renal Fibrosis / Dioscorea

Download

Portal Vein Complications in Pediatric Living Donor Liver Transplantation Using Left-Side Grafts

Treatment Outcome / Adolescent / Humans / Child / Liver / Female / Male / Infant / Liver Transplantation / Fibrosis / Newborn Infant / Body Weight / Portal vein / Female / Male / Infant / Liver Transplantation / Fibrosis / Newborn Infant / Body Weight / Portal vein

Download

Does endothelin B receptor deficiency ameliorate the induction of peritoneal fibrosis in experimental peritoneal dialysis?

Animals / Fibrosis / Behavioral Animal Models / Clinical Sciences / Rats / Peritoneal Dialysis / Wistar Rats / Peritoneum / Peritoneal Dialysis / Wistar Rats / Peritoneum

Download

Inhibition of matrix metalloproteinase activity in vivo protects against vascular hyporeactivity in endotoxemia

Engineering / Chemical Engineering / Physiology / Nutrition and Dietetics / Food Science / Fear / Compliance / Cytokines / Neurobiology of Learning and Memory / Prostate Cancer / Enzyme Inhibitors / Mast Cells / Flavonoids / Dental Materials / Extracellular Matrix / Catheterization / Anxiety / Signal Transduction / Memory / Biological Sciences / Heart Failure / Classical Conditioning / Hearing / Humans / Protein Kinases / Hemodynamics / Mice / Cues / Female / Animals / Male / American / Fibrosis / Medical Physiology / Mitogen Activated Protein Kinase / Clinical Sciences / Nutritional Biochemistry / Rats / Myocardial Infarction / Myocardium / Protease Inhibitors / Public health systems and services research / Analysis of Variance / Time Factors / Vaccinium / Tumor necrosis factor-alpha / Circulation / Matrix Metalloproteinases / Food Sciences / ANXIETY / Hydroxyproline / Ventricular Remodeling / Somatic Cell Count / MAP Kinase / Aorta / Heart Ventricles / Hydroxamic Acids / Angiotensin Converting Enzyme Inhibitors / Catabolism / Biochemistry and cell biology / Adenocarcinoma / Captopril / Lisinopril / 4-Tetrahydroisoquinolines / Matrix Metalloproteinase / Electroshock / Fear / Compliance / Cytokines / Neurobiology of Learning and Memory / Prostate Cancer / Enzyme Inhibitors / Mast Cells / Flavonoids / Dental Materials / Extracellular Matrix / Catheterization / Anxiety / Signal Transduction / Memory / Biological Sciences / Heart Failure / Classical Conditioning / Hearing / Humans / Protein Kinases / Hemodynamics / Mice / Cues / Female / Animals / Male / American / Fibrosis / Medical Physiology / Mitogen Activated Protein Kinase / Clinical Sciences / Nutritional Biochemistry / Rats / Myocardial Infarction / Myocardium / Protease Inhibitors / Public health systems and services research / Analysis of Variance / Time Factors / Vaccinium / Tumor necrosis factor-alpha / Circulation / Matrix Metalloproteinases / Food Sciences / ANXIETY / Hydroxyproline / Ventricular Remodeling / Somatic Cell Count / MAP Kinase / Aorta / Heart Ventricles / Hydroxamic Acids / Angiotensin Converting Enzyme Inhibitors / Catabolism / Biochemistry and cell biology / Adenocarcinoma / Captopril / Lisinopril / 4-Tetrahydroisoquinolines / Matrix Metalloproteinase / Electroshock

Download

Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension

Physiology / Oxidative Stress / Apoptosis / Gene expression / Pulmonary Hypertension / Probability / Molecular Mechanics / Western blotting / Heart Failure / Cardiac Hypertrophy / Anoxia / Hypertension / Low Dose / Reactive Oxygen Species / Mice / Left Ventricular Assist Device / Blood Pressure / Aldosterone / Renin Angiotensin Aldosterone System / Animals / Male / Cytochrome C / Glutathione / American / Phosphorylation / Fibrosis / Lipid metabolism / Medical Physiology / NADPH oxidase / Clinical Sciences / Chronic Renal Failure / Urinalysis / Protein kinase B / mRna expression levels / Rats / Analysis of Variance / Cardiac Output Monitoring / Left ventricular hypertrophy / Body Weight / Biological markers / Right Ventricle / Albuminuria / Cell Proliferation / Ventricular Remodeling / Angiotensin II / Ct Image of Pulmonary Artery / Vascular Injury / Heart Ventricles / Cell Survival / Nephrectomy / Mineralocorticoid Receptor / Podocytes / Glucocorticoids / Left Ventricle / Brain Natriuretic Peptide / Systolic blood pressure / Vascular Resistance / Probability / Molecular Mechanics / Western blotting / Heart Failure / Cardiac Hypertrophy / Anoxia / Hypertension / Low Dose / Reactive Oxygen Species / Mice / Left Ventricular Assist Device / Blood Pressure / Aldosterone / Renin Angiotensin Aldosterone System / Animals / Male / Cytochrome C / Glutathione / American / Phosphorylation / Fibrosis / Lipid metabolism / Medical Physiology / NADPH oxidase / Clinical Sciences / Chronic Renal Failure / Urinalysis / Protein kinase B / mRna expression levels / Rats / Analysis of Variance / Cardiac Output Monitoring / Left ventricular hypertrophy / Body Weight / Biological markers / Right Ventricle / Albuminuria / Cell Proliferation / Ventricular Remodeling / Angiotensin II / Ct Image of Pulmonary Artery / Vascular Injury / Heart Ventricles / Cell Survival / Nephrectomy / Mineralocorticoid Receptor / Podocytes / Glucocorticoids / Left Ventricle / Brain Natriuretic Peptide / Systolic blood pressure / Vascular Resistance

Download

The efficacy of single-dose 5-fluorouracil therapy in experimental caustic esophageal burn

Extracellular Matrix / Cell Division / Cell Differentiation / Animals / Pediatric Surgery / Fibrosis / Pediatric / Caustics / Rats / Esophagus / Wistar Rats / Hydroxyproline / Sodium Hydroxide / Human Fibroblasts / Experimental Model / Fibrosis / Pediatric / Caustics / Rats / Esophagus / Wistar Rats / Hydroxyproline / Sodium Hydroxide / Human Fibroblasts / Experimental Model

Download

Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice

Physiology / Inflammation / Locomotion / Mice / Transient receptor potential channels / Animals / Visceral Pain / Fibrosis / Medical Physiology / Chronic Pancreatitis / Animals / Visceral Pain / Fibrosis / Medical Physiology / Chronic Pancreatitis

Download

Alteration of Energy Substrates and ROS Production in Diabetic Cardiomyopathy

Immunology / Inflammation / Signal Transduction / DNA / Humans / Glucose / Fatty acids / Reactive Oxygen Species / Mice / Animals / Heart / Fibrosis / Lipid metabolism / Cell nucleus / Oxygen / Myocardium / Oxidation-Reduction / Adenosine Triphosphate / Glucose / Fatty acids / Reactive Oxygen Species / Mice / Animals / Heart / Fibrosis / Lipid metabolism / Cell nucleus / Oxygen / Myocardium / Oxidation-Reduction / Adenosine Triphosphate

Download

Ecto-5Nucleotidase Deficiency Exacerbates Pressure-Overload-Induced Left Ventricular Hypertrophy and Dysfunction

Genetics / Cell Division / Heart Failure / Adenosine / Protein Kinases / Hypertension / Collagen / Mice / Left Ventricular Assist Device / Blood Pressure / Animals / Fibrosis / Left Ventricular Dysfunction / Clinical Sciences / Rats / Left ventricular hypertrophy / Adaptive Response / Human Fibroblasts / Cell Size / Hypertension / Collagen / Mice / Left Ventricular Assist Device / Blood Pressure / Animals / Fibrosis / Left Ventricular Dysfunction / Clinical Sciences / Rats / Left ventricular hypertrophy / Adaptive Response / Human Fibroblasts / Cell Size

Download