Drug Targeting

Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

Myristoyl CoA: protein N-myristoyltransferase: an essential enzyme and potential drug target in kinetoplastid parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

Deep insights into Dictyocaulus viviparus transcriptomes provides unique prospects for new drug targets and disease intervention

Engineering / Bioinformatics / Technology / Molecular Biology / Caenorhabditis elegans / Biotechnology / Next generation sequencing / Transcriptome / Biological Sciences / RNA interference / Expressed Sequence Tags / Animals / Cattle / Economic Loss / Genome sequence / Protein Kinase / Anthelmintics / Large Scale / Metabolic pathway / In Silico / Drug Targeting / Dictyocaulus / Gene expression profiling / Biotechnology / Next generation sequencing / Transcriptome / Biological Sciences / RNA interference / Expressed Sequence Tags / Animals / Cattle / Economic Loss / Genome sequence / Protein Kinase / Anthelmintics / Large Scale / Metabolic pathway / In Silico / Drug Targeting / Dictyocaulus / Gene expression profiling

Deep insights into Dictyocaulus viviparus transcriptomes provides unique prospects for new drug targets and disease intervention

Engineering / Bioinformatics / Technology / Molecular Biology / Caenorhabditis elegans / Biotechnology / Next generation sequencing / Transcriptome / Biological Sciences / RNA interference / Expressed Sequence Tags / Animals / Cattle / Economic Loss / Genome sequence / Protein Kinase / Anthelmintics / Large Scale / Metabolic pathway / In Silico / Drug Targeting / Dictyocaulus / Gene expression profiling / Biotechnology / Next generation sequencing / Transcriptome / Biological Sciences / RNA interference / Expressed Sequence Tags / Animals / Cattle / Economic Loss / Genome sequence / Protein Kinase / Anthelmintics / Large Scale / Metabolic pathway / In Silico / Drug Targeting / Dictyocaulus / Gene expression profiling

Quinuclidine Derivatives as Potential Antiparasitics

Microbiology / Medical Microbiology / Animals / Enzyme / Rats / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure

Quinuclidine Derivatives as Potential Antiparasitics

Microbiology / Medical Microbiology / Animals / Enzyme / Rats / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure

Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis

Cell Cycle / Gene expression / Multidisciplinary / Chemokines and chemokine receptors / Cercopithecus aethiops / Humans / Mice / Female / Animals / Cytomegalovirus / Phenotype / Spectrum / Viral Infection / Neoplasms / G protein / Drug Targeting / Tumor Progression / Nude mice / Vascular Endothelial Growth Factor / Cell Growth / Humans / Mice / Female / Animals / Cytomegalovirus / Phenotype / Spectrum / Viral Infection / Neoplasms / G protein / Drug Targeting / Tumor Progression / Nude mice / Vascular Endothelial Growth Factor / Cell Growth

Lipids as clinical drugs, lipids as drug targets

Physical sciences / CHEMICAL SCIENCES / Estudents / Drug Targeting

Biochemical characterization of enterovirus 71 3D RNA polymerase

Genetics / Kinetics / RNA polymerase / Biological Sciences / Humans / Physical sciences / Enzyme / Reverse Transcriptase / Protein Binding / Drug Targeting / Nucleotides / Physical sciences / Enzyme / Reverse Transcriptase / Protein Binding / Drug Targeting / Nucleotides

Polysialic acids: potential in drug delivery

Pharmacokinetics / Drug delivery / Dosage Form / Mice / Animals / Male / Shell Half-Life / Drug Targeting / Drug Carriers / Biochemistry and cell biology / Sialic Acids / Fluorescein / Carbohydrate Sequence / Molecular Sequence Data / Male / Shell Half-Life / Drug Targeting / Drug Carriers / Biochemistry and cell biology / Sialic Acids / Fluorescein / Carbohydrate Sequence / Molecular Sequence Data

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