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Drug Targeting
Drug Targeting
Lipids as clinical drugs, lipids as drug targets
Physical sciences / CHEMICAL SCIENCES / Estudents / Drug Targeting
Quinuclidine Derivatives as Potential Antiparasitics
Microbiology / Medical Microbiology / Animals / Enzyme / Rats / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure
Unusual Developmental Pattern of Expression of Enzymes Involved in DNA Biosynthesis in Trichinella spiralis and Trichinella pseudospiralis
Cell Cycle / Confocal Microscopy / Enzyme / Skeletal Muscle / Western blot / Thymidine Kinase / Monoclonal Antibody / Cell Proliferation / Drug Targeting / DNA Polymerase / Small Intestine / Dihydrofolate Reductase / Dna Synthesis / Thymidine Kinase / Monoclonal Antibody / Cell Proliferation / Drug Targeting / DNA Polymerase / Small Intestine / Dihydrofolate Reductase / Dna Synthesis
TRP channels as potential drug targets
Calcium / Prostate Cancer / Transient receptor potential channels / Animals / Calcium channels / Cell Proliferation / Drug Targeting / Intracellular Signaling / Biochemistry and cell biology / Calcium Channel Blockers / Cell Proliferation / Drug Targeting / Intracellular Signaling / Biochemistry and cell biology / Calcium Channel Blockers
Peptide Deformylase Inhibitors as Potent Antimycobacterial Agents
Genetics / Microbiology / Medical Microbiology / Drug development / Protein synthesis / Tuberculosis / Mycobacterium tuberculosis / Escherichia coli / Mycobacterium / Mice / Female / Animals / Plasmids / Enzyme / Antibacterial activity / Anti-Bacterial Agents / Buffers / Protease Inhibitors / Antimicrobial agents / Microbial Sensitivity Tests / Culture Media / Recombinant Protein / Drug Targeting / Mycobacterium bovis / Tuberculosis / Mycobacterium tuberculosis / Escherichia coli / Mycobacterium / Mice / Female / Animals / Plasmids / Enzyme / Antibacterial activity / Anti-Bacterial Agents / Buffers / Protease Inhibitors / Antimicrobial agents / Microbial Sensitivity Tests / Culture Media / Recombinant Protein / Drug Targeting / Mycobacterium bovis
Reconsidering GHB: orphan drug or new model antidepressant?
Psychopharmacology / Oxytocin / Humans / Animals / Animal Model / Depressive Disorder / Research Method / Spectrum / Mode of action / Drug Targeting / Depressive Disorder / Research Method / Spectrum / Mode of action / Drug Targeting
Targeting nucleotide dimers containing antiviral nucleosides
Drug delivery / Enzyme / Viral Infection / Combination drug therapy / Side Effect / Drug Targeting / Nucleotides / Drug Targeting / Nucleotides
Sequencing, bioinformatic characterization and expression pattern of a putative amino acid transporter from the parasitic cestode Echinococcus granulosus
Genetics / Functional Analysis / Computational Biology / Immunohistochemistry / Gene expression / Animals / Similarity Search / Gene / Western blot / Amino Acid Profile / Molecular Mass / Amino Acid Sequence / Cystic Echinococcosis / Drug Targeting / IT Evaluation / cDNA library / Echinococcus granulosus / Animals / Similarity Search / Gene / Western blot / Amino Acid Profile / Molecular Mass / Amino Acid Sequence / Cystic Echinococcosis / Drug Targeting / IT Evaluation / cDNA library / Echinococcus granulosus
Genuine DNA/polyethylenimine (PEI) Complexes Improve Transfection Properties and Cell Survival
Ultrafiltration / Drug / DNA / Humans / Mice / Female / Animals / Plasmids / Lung / HeLa cells / Transfection / Drug Targeting / Cell Survival / Ligands / Polyethylenimine / Polyethylene Glycols / Polyethyleneimine / Female / Animals / Plasmids / Lung / HeLa cells / Transfection / Drug Targeting / Cell Survival / Ligands / Polyethylenimine / Polyethylene Glycols / Polyethyleneimine
Genuine DNA/polyethylenimine (PEI) Complexes Improve Transfection Properties and Cell Survival
Ultrafiltration / Drug / DNA / Humans / Mice / Female / Animals / Plasmids / Lung / HeLa cells / Transfection / Drug Targeting / Cell Survival / Ligands / Polyethylenimine / Polyethylene Glycols / Polyethyleneimine / Female / Animals / Plasmids / Lung / HeLa cells / Transfection / Drug Targeting / Cell Survival / Ligands / Polyethylenimine / Polyethylene Glycols / Polyethyleneimine
La melatonina: un coadyuvante potencial en el tratamiento de las demencias
Free Radical / Nitric oxide / Blood brain barrier / Acetylcholinesterase / Salud Mental / Glutathione Peroxidase / Salud / Actin Dynamics / Mental Disorder / Superoxide Dismutase / Clinical Sciences / Antioxidant enzyme / Neuronal Death / Calmodulin / Neurodegenerative Disease / Singlet Oxygen / Pineal Gland / Cellular Structure / Glutathione Reductase / Drug Targeting / Brain Damage / Paired Helical Filament / Senile Plaques / Glutathione Peroxidase / Salud / Actin Dynamics / Mental Disorder / Superoxide Dismutase / Clinical Sciences / Antioxidant enzyme / Neuronal Death / Calmodulin / Neurodegenerative Disease / Singlet Oxygen / Pineal Gland / Cellular Structure / Glutathione Reductase / Drug Targeting / Brain Damage / Paired Helical Filament / Senile Plaques
La melatonina: un coadyuvante potencial en el tratamiento de las demencias
Free Radical / Nitric oxide / Blood brain barrier / Acetylcholinesterase / Salud Mental / Glutathione Peroxidase / Salud / Actin Dynamics / Mental Disorder / Superoxide Dismutase / Clinical Sciences / Antioxidant enzyme / Neuronal Death / Calmodulin / Neurodegenerative Disease / Singlet Oxygen / Pineal Gland / Cellular Structure / Glutathione Reductase / Drug Targeting / Brain Damage / Paired Helical Filament / Senile Plaques / Glutathione Peroxidase / Salud / Actin Dynamics / Mental Disorder / Superoxide Dismutase / Clinical Sciences / Antioxidant enzyme / Neuronal Death / Calmodulin / Neurodegenerative Disease / Singlet Oxygen / Pineal Gland / Cellular Structure / Glutathione Reductase / Drug Targeting / Brain Damage / Paired Helical Filament / Senile Plaques
Entamoeba histolytica: Biochemical characterization of a protein disulfide isomerase
Microbiology / Protein Folding / Life Style / Molecular chaperones / Experimental parasitology / Insulin / Oxidoreductases / Enzyme / Experimental / Anti-Bacterial Agents / Entamoeba histolytica / Veterinary Sciences / Drug Targeting / Hydrogen-Ion Concentration / Disulfide bond / Insulin / Oxidoreductases / Enzyme / Experimental / Anti-Bacterial Agents / Entamoeba histolytica / Veterinary Sciences / Drug Targeting / Hydrogen-Ion Concentration / Disulfide bond
Targeting nucleotide dimers containing antiviral nucleosides
Drug delivery / Enzyme / Viral Infection / Combination drug therapy / Side Effect / Drug Targeting / Nucleotides / Drug Targeting / Nucleotides
Leishmania major CorA-like magnesium transporters play a critical role in parasite development and virulence
Microbiology / Zoology / Macrophages / Virulence / Protein Design / Magnesium / Mice / Animals / Endoplasmic Reticulum / Life Cycle / Membrane transport proteins / For / Cutaneous Leishmaniasis / Veterinary Sciences / Protozoan Proteins / Ion Transport / Virulence Factors / Structural Similarity Index / Drug Targeting / Leishmania Major / Magnesium / Mice / Animals / Endoplasmic Reticulum / Life Cycle / Membrane transport proteins / For / Cutaneous Leishmaniasis / Veterinary Sciences / Protozoan Proteins / Ion Transport / Virulence Factors / Structural Similarity Index / Drug Targeting / Leishmania Major
Lipids as clinical drugs, lipids as drug targets
Physical sciences / CHEMICAL SCIENCES / Estudents / Drug Targeting
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