Cell line

Tissue-specific Microvascular Endothelial Cell Lines from H-2K

Immunology / Cancer / Flow Cytometry / Cytokines / Immunohistochemistry / Immunology of the Gut / Molecular Mechanics / Cell Culture / Cell Division / Cell line / Cell Differentiation / Humans / Natural Killer cells / Kidney / Endothelial Cells / Collagen / Mice / Female / Animals / Male / Young Adult / Vascular endothelium / Lung / Aged / Middle Aged / Proteoglycans / Adult / Endothelial cell / Dermis / Neoplasms / Primary Culture / Tumor Growth / Low Density Lipoprotein (LDL) / Microscopic Polyangiitis Market / Temperature Sensitive Polymer / Tumor Progression / Tissue Specificity / Laminin / Immunology of the Gut / Molecular Mechanics / Cell Culture / Cell Division / Cell line / Cell Differentiation / Humans / Natural Killer cells / Kidney / Endothelial Cells / Collagen / Mice / Female / Animals / Male / Young Adult / Vascular endothelium / Lung / Aged / Middle Aged / Proteoglycans / Adult / Endothelial cell / Dermis / Neoplasms / Primary Culture / Tumor Growth / Low Density Lipoprotein (LDL) / Microscopic Polyangiitis Market / Temperature Sensitive Polymer / Tumor Progression / Tissue Specificity / Laminin

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

Immunology / MicroRNA / Inflammation / Macrophages / Signal Transduction / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation / Molecular Sequence Data / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation / Molecular Sequence Data

Comprehensive identification and characterization of diallelic insertion-deletion polymorphisms in 330 human candidate genes

Polymorphism / Computational Biology / Population Genetics / Systems Biology / Calcium / System Biology / Gene expression / Low Frequency / Biological Sciences / Molecular / Association study / Cercopithecus aethiops / Cell line / Humans / Genetic Testing / Microarray / Mice / Animals / Human Molecular Genetics / Gene Network / Genome / Genes / Integrated Approach / Human Genome / Myocardium / Correlation Analysis / Linkage Disequilibrium / Base Sequence / In Silico / Subcellular Fractions / Calcium Binding Protein / Protein Transport / Allele Frequency / Microarray Data / DNA mutational analysis / System Biology / Gene expression / Low Frequency / Biological Sciences / Molecular / Association study / Cercopithecus aethiops / Cell line / Humans / Genetic Testing / Microarray / Mice / Animals / Human Molecular Genetics / Gene Network / Genome / Genes / Integrated Approach / Human Genome / Myocardium / Correlation Analysis / Linkage Disequilibrium / Base Sequence / In Silico / Subcellular Fractions / Calcium Binding Protein / Protein Transport / Allele Frequency / Microarray Data / DNA mutational analysis

Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors

Organic Chemistry / Enzyme Inhibitors / Bioorganic Chemistry / Cell line / Humans / Proteasome / Amino Acids / Active site / Amino Acid Profile / Bioorganic / PROTEASOME INHIBITOR / Proteasome / Amino Acids / Active site / Amino Acid Profile / Bioorganic / PROTEASOME INHIBITOR

Intracellular expression of antisense RNA transcripts complementary to the human immunodeficiency virus type-1 vif gene inhibits viral replication in infected T-lymphoblastoid cells

Gene Therapy / HIV / Cell line / Humans / Biochemical / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation

Intracellular expression of antisense RNA transcripts complementary to the human immunodeficiency virus type-1 vif gene inhibits viral replication in infected T-lymphoblastoid cells

Gene Therapy / HIV / Cell line / Humans / Biochemical / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation

Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis

Thermodynamics / Molecular Biology / Computational Biology / Gene Silencing / Global Analysis / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus

Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis

Thermodynamics / Molecular Biology / Computational Biology / Gene Silencing / Global Analysis / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus

Spodoptera exigua multicapsid nucleopolyhedrovirus deletion mutants generated in cell culture lack virulence in vivo

Genetics / Cell Culture / Biological Sciences / Virulence / Cell line / General / Animals / Physical Map / Host Range / Spodoptera exigua / General / Animals / Physical Map / Host Range / Spodoptera exigua

Lipopolysaccharide Internalization Activates Endotoxin-Dependent Signal Transduction in Cardiomyocytes

Electron Microscopy / Transmission Electron Microscopy / Fluorescent Dyes and Reagents / Confocal Microscopy / Signal Transduction / Lipopolysaccharide / Cell line / Endocytosis / Animals / NF-kappa B / Phosphorylation / Clinical Sciences / Lipopolysaccharides / Rats / Nitric Oxide Synthase / Myocardium / Tumor necrosis factor-alpha / Circulation / Wistar Rats / Lysosomes / Golgi Apparatus / Boron Compounds / Lipopolysaccharide / Cell line / Endocytosis / Animals / NF-kappa B / Phosphorylation / Clinical Sciences / Lipopolysaccharides / Rats / Nitric Oxide Synthase / Myocardium / Tumor necrosis factor-alpha / Circulation / Wistar Rats / Lysosomes / Golgi Apparatus / Boron Compounds

miR-Sens--a retroviral dual-luciferase reporter to detect microRNA activity in primary cells

RNA / Gene expression / Cell line / Humans / Mice / Animals / Gene Order / microRNAs / Base Sequence / Poly A / Protein Biosynthesis / Biochemistry and cell biology / Molecular Sequence Data / Animals / Gene Order / microRNAs / Base Sequence / Poly A / Protein Biosynthesis / Biochemistry and cell biology / Molecular Sequence Data

An estrogen receptor chimera senses ligands by nuclear translocation

Biochemistry / Fluorescence Microscopy / Drug Discovery / Fluorescent Dyes and Reagents / STEROIDS / High Content Screening / Estrogen Receptor / Cercopithecus aethiops / Dexamethasone / Cell line / Humans / Mice / Animals / Immunoprecipitation / Tamoxifen / Time Factors / Transfection / Protein Binding / Cytoplasm / Ligands / Glucocorticoids / Estradiol / Protein Transport / Biochemistry and cell biology / High Content Screening / Estrogen Receptor / Cercopithecus aethiops / Dexamethasone / Cell line / Humans / Mice / Animals / Immunoprecipitation / Tamoxifen / Time Factors / Transfection / Protein Binding / Cytoplasm / Ligands / Glucocorticoids / Estradiol / Protein Transport / Biochemistry and cell biology

In vitro and in vivo profile of 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity

Organic Chemistry / Medicinal Chemistry / Obesity / Pharmacokinetics / Pharmaceutical Chemistry / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity

DNA damaging agents improve stable gene transfer efficiency in mammalian cells

Radiation / DNA damage / Cell line / Humans / Mice / Animals / Gene transfer techniques / Hydrogen Peroxide / Transfection / Recombination / Gene Transfer / Animals / Gene transfer techniques / Hydrogen Peroxide / Transfection / Recombination / Gene Transfer

DNA methylation and Yin Yang1 repress adenosine A2A receptor levels in human brain: ZBP-89 and Yin Yang1 control ADORA2A expression

RNA / Neurochemistry / Transcription Factors / Western blotting / Cell line / Humans / Cerebellum / Female / Male / DNA methylation / Immunoprecipitation / Aged / Middle Aged / Transfection / Base Sequence / Brain Chemistry / Putamen / DNA binding proteins / Neurosciences / Molecular Sequence Data / Humans / Cerebellum / Female / Male / DNA methylation / Immunoprecipitation / Aged / Middle Aged / Transfection / Base Sequence / Brain Chemistry / Putamen / DNA binding proteins / Neurosciences / Molecular Sequence Data

The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect
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