Catechols

New antimalarial and cytotoxic 4-nerolidylcatechol derivatives

Organic Chemistry / Humans / Solvent Extraction / Multidrug Resistance / Animals / Drug Resistance / Central Nervous System / Plant Roots / European / Plant extracts / Piperaceae / Plasmodium falciparum / Antimalarials / Ambient Temperature / Catechols / Nervous System / Cell Proliferation / Colon Carcinoma / Molecular Structure / Drug Resistance / Central Nervous System / Plant Roots / European / Plant extracts / Piperaceae / Plasmodium falciparum / Antimalarials / Ambient Temperature / Catechols / Nervous System / Cell Proliferation / Colon Carcinoma / Molecular Structure

New antimalarial and cytotoxic 4-nerolidylcatechol derivatives

Organic Chemistry / Humans / Solvent Extraction / Multidrug Resistance / Animals / Drug Resistance / Central Nervous System / Plant Roots / European / Plant extracts / Piperaceae / Plasmodium falciparum / Antimalarials / Ambient Temperature / Catechols / Nervous System / Cell Proliferation / Colon Carcinoma / Molecular Structure / Drug Resistance / Central Nervous System / Plant Roots / European / Plant extracts / Piperaceae / Plasmodium falciparum / Antimalarials / Ambient Temperature / Catechols / Nervous System / Cell Proliferation / Colon Carcinoma / Molecular Structure

Systemic catechol-O-methyl transferase inhibition enables the D1 agonist radiotracer R-[11C]SKF 82957

Enzyme Inhibitors / Positron Emission Tomography / Brain / Nitriles / Animals / Benzophenones / Clinical Sciences / Rats / Catechols / Metabolic pathway / Radiopharmaceuticals / Benzophenones / Clinical Sciences / Rats / Catechols / Metabolic pathway / Radiopharmaceuticals

New antimalarial and cytotoxic 4-nerolidylcatechol derivatives

Organic Chemistry / Humans / Solvent Extraction / Multidrug Resistance / Animals / Drug Resistance / Central Nervous System / Plant Roots / European / Plant extracts / Piperaceae / Plasmodium falciparum / Antimalarials / Ambient Temperature / Catechols / Nervous System / Cell Proliferation / Colon Carcinoma / Molecular Structure / Drug Resistance / Central Nervous System / Plant Roots / European / Plant extracts / Piperaceae / Plasmodium falciparum / Antimalarials / Ambient Temperature / Catechols / Nervous System / Cell Proliferation / Colon Carcinoma / Molecular Structure

New antimalarial and cytotoxic 4-nerolidylcatechol derivatives

Organic Chemistry / Humans / Solvent Extraction / Multidrug Resistance / Animals / Drug Resistance / Central Nervous System / Plant Roots / European / Plant extracts / Piperaceae / Plasmodium falciparum / Antimalarials / Ambient Temperature / Catechols / Nervous System / Cell Proliferation / Colon Carcinoma / Molecular Structure / Drug Resistance / Central Nervous System / Plant Roots / European / Plant extracts / Piperaceae / Plasmodium falciparum / Antimalarials / Ambient Temperature / Catechols / Nervous System / Cell Proliferation / Colon Carcinoma / Molecular Structure

Entacapone, a novel catechol-O-methyltransferase inhibitor for Parkinson\'s disease, does not impair mitochondrial energy production

Kinetics / Enzyme Inhibitors / Mitochondria / Energy Metabolism / Cell Culture / Cell line / Nitriles / Mice / Female / Animals / Male / Heart / European / Energy Production / Rats / Oxidative phosphorylation / Guinea Pig / Catechols / Wistar Rats / Oxygen Consumption / Cardiac function / Cell line / Nitriles / Mice / Female / Animals / Male / Heart / European / Energy Production / Rats / Oxidative phosphorylation / Guinea Pig / Catechols / Wistar Rats / Oxygen Consumption / Cardiac function

Detoxication of Structurally Diverse Polycyclic Aromatic Hydrocarbon (PAH) o-Quinones by Human Recombinant Catechol-O-methyltransferase (COMT) via O-Methylation of PAH Catechols

Kinetics / Biological Chemistry / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / Methylation / Animals / Quinones / Lung / CHEMICAL SCIENCES / Polycyclic aromatic hydrocarbons (PAHs) / Oxygen / Swine / Catechols / Recombinant Proteins / Methylation / Animals / Quinones / Lung / CHEMICAL SCIENCES / Polycyclic aromatic hydrocarbons (PAHs) / Oxygen / Swine / Catechols / Recombinant Proteins

Potential of Cometabolic Transformation of Polysaccharides and Lignin in Lignocellulose by Soil Actinobacteria

Kinetics / Biomass / Multidisciplinary / Cellulose / Streptomyces / Populus / Lignin / Trees / PLoS one / Soil Microbiology / Catechols / Hydrolysis / Populus / Lignin / Trees / PLoS one / Soil Microbiology / Catechols / Hydrolysis

Pharmacokinetic-pharmacodynamic crossover comparison of two levodopa extension strategies

Cognitive Science / Pharmacokinetics / Comparative Study / Movement disorders / Strategy / Humans / Nitriles / Female / Male / Drug Delivery Systems / Levodopa / Fluctuations / Clinical Sciences / Aged / Middle Aged / Pharmacodynamics / Analysis of Variance / Time Factors / Retrospective Studies / Catechols / Combination drug therapy / Cross-Over Studies / Parkinson Disease / Carbidopa / Severity of Illness Index / Disability Evaluation / Humans / Nitriles / Female / Male / Drug Delivery Systems / Levodopa / Fluctuations / Clinical Sciences / Aged / Middle Aged / Pharmacodynamics / Analysis of Variance / Time Factors / Retrospective Studies / Catechols / Combination drug therapy / Cross-Over Studies / Parkinson Disease / Carbidopa / Severity of Illness Index / Disability Evaluation

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