Biochemistry and cell biology

N-terminal amphipathic helix as a trigger of hemolytic activity in antimicrobial peptides: A case study in latarcins

Biochemistry / Microbiology / Immunology / Molecular Biology / Computational Biology / Protein Engineering / Molecular modeling / Mutation / EC / Case Study / Animals / Antimicrobial Peptide / AMPs / Antimicrobial Cationic Peptides / Protein Secondary Structure Prediction / Cytotoxic Activity / Ec / Amino Acid Sequence / In Silico / Biochemistry and cell biology / Hemolysis / Proof of Concept / Protein Engineering / Molecular modeling / Mutation / EC / Case Study / Animals / Antimicrobial Peptide / AMPs / Antimicrobial Cationic Peptides / Protein Secondary Structure Prediction / Cytotoxic Activity / Ec / Amino Acid Sequence / In Silico / Biochemistry and cell biology / Hemolysis / Proof of Concept

Expression, Purification, and Partial Characterization of HCV RNA Polymerase

RNA polymerase / Biological Sciences / Escherichia coli / Glutathione / Hepatitis C Virus / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Inclusion Bodies / Molecular cloning / Molecular weight / Enzymatic Activity / Fusion Protein / Biochemistry and cell biology / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Inclusion Bodies / Molecular cloning / Molecular weight / Enzymatic Activity / Fusion Protein / Biochemistry and cell biology

Amino acid sequence, biochemical characterization, and comparative modeling of a nonspecific lipid transfer protein from Amaranthus hypochondriacus

Protein Folding / Mass Spectrometry / Lipids / Circular Dichroism / Maize / High Performance Liquid Chromatography / PLANT DEFENSE / High Pressure Liquid Chromatography / Protein Sequence Analysis / Secondary Structure / Amaranthus / Protein Secondary Structure Prediction / Comparative modeling / Molecular Mass / Plant species / Molecular weight / Species Specificity / Amino Acid Sequence / Protein Binding / PLANT PROTEINS / Biochemistry and cell biology / High Performance Liquid Chromatography / PLANT DEFENSE / High Pressure Liquid Chromatography / Protein Sequence Analysis / Secondary Structure / Amaranthus / Protein Secondary Structure Prediction / Comparative modeling / Molecular Mass / Plant species / Molecular weight / Species Specificity / Amino Acid Sequence / Protein Binding / PLANT PROTEINS / Biochemistry and cell biology

Mass production of basal bodies in paraspermiogenesis of Tubificinae (Annelida, Oligochaeta)

Electron Microscopy / Fluorescence Microscopy / Spermatogenesis / Animals / Male / Oligochaeta / Centrioles / Spermatozoa / Biochemistry and cell biology / Oligochaeta / Centrioles / Spermatozoa / Biochemistry and cell biology

Mastoparan effects in skeletal muscle damage: An ultrastructural view until now concealed

Materials Engineering / Microscopy / Skeletal muscle biology / Transmission Electron Microscopy / Mitochondria / Wasps / Mice / Animals / Male / Peptides / Skeletal Muscle / Biochemistry and cell biology / Sarcoplasmic reticulum / Wasps / Mice / Animals / Male / Peptides / Skeletal Muscle / Biochemistry and cell biology / Sarcoplasmic reticulum

Transition-State Analogue γ-Secretase Inhibitors Stabilize a 900 kDa Presenilin/Nicastrin Complex †

Biochemistry / Photochemistry / Membrane Proteins / Humans / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Solubility / Protease Inhibitors / Presenilin-2 / Molecular weight / Detergents / Subcellular Fractions / Protein Binding / Carbamates / Biochemistry and cell biology / Solubility / Protease Inhibitors / Presenilin-2 / Molecular weight / Detergents / Subcellular Fractions / Protein Binding / Carbamates / Biochemistry and cell biology

Structural polymorphism of two CPP: An important parameter of activity

Chemical Engineering / Polymorphism / Biological Sciences / Physical sciences / Protein Conformation / Amino Acid Sequence / Galanin / Biochemistry and cell biology / Amino Acid Sequence / Galanin / Biochemistry and cell biology

Glutaminyl Cyclases Display Significant Catalytic Proficiency for Glutamyl Substrates

Biochemistry / Catalysis / Amyloid / Humans / Animals / Glutamine / Substrate Specificity / Cyclization / Alzheimer Disease / Biochemistry and cell biology / Glutamine / Substrate Specificity / Cyclization / Alzheimer Disease / Biochemistry and cell biology

Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells

Genetics / Epigenetics / Colorectal cancer / Humans / Glucose / Cancer Therapy / Ischemia / DNA methylation / Enzyme / Carbonic anhydrase / Carcinoma / Oxygen / Western blot / Tumor Progression / Biochemistry and cell biology / Colorectal Neoplasms / Cancer Therapy / Ischemia / DNA methylation / Enzyme / Carbonic anhydrase / Carcinoma / Oxygen / Western blot / Tumor Progression / Biochemistry and cell biology / Colorectal Neoplasms

Peroxisomal ABC transporters

Fatty acids / Animals / Plants / Lipid metabolism / Environmental Conditions / Peroxisomes / Oxidation-Reduction / Biochemistry and cell biology / Functional Dependency / Peroxisomes / Oxidation-Reduction / Biochemistry and cell biology / Functional Dependency

Heterodimer formation is essential for heparanase enzymatic activity

Extracellular Matrix / Western blotting / Cell line / Humans / Processing / Peptides / Glucuronidase / Biochemical / Plasmids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Molecular cloning / Amino Acids / Amino Acid Profile / Transfection / Glutathione Transferase / Enzymatic Activity / Biochemistry and cell biology / Dimerization / Immunoblotting / Peptides / Glucuronidase / Biochemical / Plasmids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Molecular cloning / Amino Acids / Amino Acid Profile / Transfection / Glutathione Transferase / Enzymatic Activity / Biochemistry and cell biology / Dimerization / Immunoblotting

Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H + cotransporter (NupC) produced in Xenopus laevis oocytes

Kinetics / Molecular / Humans / Sequence alignment / Escherichia coli / Female / Animals / Membrane transport proteins / Protein Sequence Analysis / Substrate Specificity / Xenopus laevis / Oocytes / Nucleosides / Recombinant Proteins / Antineoplastic Agents / Antiviral Agents / Biochemistry and cell biology / Female / Animals / Membrane transport proteins / Protein Sequence Analysis / Substrate Specificity / Xenopus laevis / Oocytes / Nucleosides / Recombinant Proteins / Antineoplastic Agents / Antiviral Agents / Biochemistry and cell biology

Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin-induced intestinal damage

Catalysis / British / Porphyrins / Intestinal Mucosa / Animals / Male / Nitrates / Superoxide Dismutase / Lipid peroxidation / Neutrophils / Lipopolysaccharides / Colchicine / Rats / Organometallic Compounds / Ferric Compounds / Oxidants / Superoxides / Biochemistry and cell biology / Male / Nitrates / Superoxide Dismutase / Lipid peroxidation / Neutrophils / Lipopolysaccharides / Colchicine / Rats / Organometallic Compounds / Ferric Compounds / Oxidants / Superoxides / Biochemistry and cell biology

Electromechanical model of excitable tissue to study reentrant cardiac arrhythmias

Finite element method / Cellular mechanotransduction / Humans / Computer Simulation / Animals / Feedback / Large Deformation Mechanics / Cardiac Arrhythmias / Finite Difference Method / Action Potentials / Body Surface Potential Mapping / Biochemistry and cell biology / Feedback / Large Deformation Mechanics / Cardiac Arrhythmias / Finite Difference Method / Action Potentials / Body Surface Potential Mapping / Biochemistry and cell biology

Specific amino acid recognition by aspartyl-tRNA synthetase studied by free energy simulations

Molecular Biology / Molecular / Sequence alignment / Computer Simulation / Free Energy / Amino Acids / Amino Acid Profile / Protein Conformation / Amino Acid Sequence / Asparagine / Biochemistry and cell biology / Amino Acids / Amino Acid Profile / Protein Conformation / Amino Acid Sequence / Asparagine / Biochemistry and cell biology

Cellular prion protein regulates intracellular hydrogen peroxide level and prevents copper-induced apoptosis

Flow Cytometry / Apoptosis / Cerebellum / Copper / Mice / Animals / Cell Death / Neurons / Hydrogen Peroxide / Cell nucleus / Prions / Time Factors / Protein Binding / Cell Survival / Biochemistry and cell biology / Prion Protein / Animals / Cell Death / Neurons / Hydrogen Peroxide / Cell nucleus / Prions / Time Factors / Protein Binding / Cell Survival / Biochemistry and cell biology / Prion Protein
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