Biochemistry and cell biology

Design and characterization of a novel cellular prion-derived quenched fluorimetric substrate of α-secretase

Membrane Proteins / Protein Engineering / Cell line / Humans / Kidney / Mice / Animals / Biochemical / Prion disease / Substrate Specificity / Amino Acid Profile / Transfection / Human Fibroblasts / Serine Protease / Fluorometry / Biochemistry and cell biology / Prion Protein / Mice / Animals / Biochemical / Prion disease / Substrate Specificity / Amino Acid Profile / Transfection / Human Fibroblasts / Serine Protease / Fluorometry / Biochemistry and cell biology / Prion Protein

The subunit composition of human extracellular superoxide dismutase (EC-SOD) regulate enzymatic activity

Antioxidants / Humans / Animals / Superoxide Dismutase / Swine / Extracellular Space / Biochemistry and cell biology / Dimerization / Extracellular Space / Biochemistry and cell biology / Dimerization

Microstructural characteristics of calcium hydroxyapatite/poly-L-lactide based composites

Materials Engineering / Condensed Matter Physics / Microscopy / Scanning Electron Microscopy / Temperature / Bone Substitutes / Durapatite / Polyesters / Biocompatible Materials / Biochemistry and cell biology / Bone Substitutes / Durapatite / Polyesters / Biocompatible Materials / Biochemistry and cell biology

Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease

Protein Folding / Kinetics / Humans / Mutation / Male / Microtubules / Glycolysis / Triosephosphate Isomerase / Biochemistry and cell biology / Pentose Phosphate Pathway / Microtubules / Glycolysis / Triosephosphate Isomerase / Biochemistry and cell biology / Pentose Phosphate Pathway

Triosephosphate isomerase deficiency: New insights into an enigmatic disease

Genetics / Early Childhood / Energy Metabolism / Biological Sciences / Drosophila / Age / Mice / Animals / Physical sciences / Animal Model / Glycolysis / Lipid metabolism / Enzyme / Clinical Sciences / Model System / Triosephosphate Isomerase / Recombinant Protein / Autosomal Recessive / Catalytic Activity / Biochemistry and cell biology / Pentose Phosphate Pathway / Ad / Hemolytic Anemia / Age / Mice / Animals / Physical sciences / Animal Model / Glycolysis / Lipid metabolism / Enzyme / Clinical Sciences / Model System / Triosephosphate Isomerase / Recombinant Protein / Autosomal Recessive / Catalytic Activity / Biochemistry and cell biology / Pentose Phosphate Pathway / Ad / Hemolytic Anemia

Yarrowia lipolytica as a model for bio-oil production

Genetics / Oils / Lipid metabolism / Physiological Response / Triglycerides / Enzyme / Single Cell / Fermentation / Fatty Acid / Biological Process / Yarrowia / Cytoplasm / Oxidation-Reduction / Biochemistry and cell biology / Cultural Control / Enzyme / Single Cell / Fermentation / Fatty Acid / Biological Process / Yarrowia / Cytoplasm / Oxidation-Reduction / Biochemistry and cell biology / Cultural Control

NLRP1a Expression in Srebp-1a-Deficient Mice

Macrophages / Innate immunity / Animals / Male / Lipid metabolism / Biochemistry and cell biology

3Methyladenine–DNA Glycosylase I from Escherichia coli—Computer Modeling and Supporting Experimental Evidence

Algorithms / Computer Simulation / Circular Dichroism / Escherichia coli / Biochemical / Enzyme / Protein Secondary Structure Prediction / Three Dimensional / Cysteine / Protein Conformation / Amino Acid Sequence / Biochemistry and cell biology / Enzyme / Protein Secondary Structure Prediction / Three Dimensional / Cysteine / Protein Conformation / Amino Acid Sequence / Biochemistry and cell biology

Substrate specificity of recombinant dengue 2 virus NS2B-NS3 protease: Influence of natural and unnatural basic amino acids on hydrolysis of synthetic fluorescent substrates

Kinetics / Fluorescent Dyes and Reagents / Fluorescence Resonance Energy Transfer / Substrate Specificity / Amino Acid Profile / Non-structural Measure / Salts / Recombinant Proteins / Hydrolysis / Hydrogen-Ion Concentration / Biochemistry and cell biology / Furin / Non-structural Measure / Salts / Recombinant Proteins / Hydrolysis / Hydrogen-Ion Concentration / Biochemistry and cell biology / Furin

BYC, an atypical aspartic endopeptidase from Rhipicephalus (Boophilus) microplus eggs

Physiology / Immune response / Catalysis / Mass Spectrometry / Fluorescence / Catalytic Mechanism / Humans / Female / Animals / Peptides / D-Aspartic Acid / High Performance Liquid Chromatography / Cattle / Molecular cloning / Protein Sequence Analysis / Specific Activity / Substrate Specificity / Protein Conformation / Amino Acid Sequence / Recombinant Proteins / Rhipicephalus (Boophilus) microplus / Catalytic Activity / Biochemistry and cell biology / Rhipicephalus / Catalytic Mechanism / Humans / Female / Animals / Peptides / D-Aspartic Acid / High Performance Liquid Chromatography / Cattle / Molecular cloning / Protein Sequence Analysis / Specific Activity / Substrate Specificity / Protein Conformation / Amino Acid Sequence / Recombinant Proteins / Rhipicephalus (Boophilus) microplus / Catalytic Activity / Biochemistry and cell biology / Rhipicephalus

S 1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids

Thermodynamics / Kinetics / Humans / Animals / Drug Design / Peptides / Substrate Specificity / Cysteine endopeptidases / Amino Acid Profile / Protozoan Proteins / Recombinant Proteins / Hydrolysis / Biochemistry and cell biology / Cysteine Proteinase Inhibitors / Peptides / Substrate Specificity / Cysteine endopeptidases / Amino Acid Profile / Protozoan Proteins / Recombinant Proteins / Hydrolysis / Biochemistry and cell biology / Cysteine Proteinase Inhibitors

In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitized individuals

Algorithms / Molecular Medicine / Cell Division / Molecular / Humans / Peptides / Glycoproteins / Enzyme Linked Immunosorbent Assay / Predictive value of tests / Paracoccidioides / Biochemistry and cell biology / Cohort Studies / Immunoblotting / Peptides / Glycoproteins / Enzyme Linked Immunosorbent Assay / Predictive value of tests / Paracoccidioides / Biochemistry and cell biology / Cohort Studies / Immunoblotting

Erythropoietin administration partially prevents adipose tissue loss in experimental cancer cachexia models

Skeletal muscle biology / Adipose tissue / Erythropoietin / Cell Differentiation / Mice / Animals / Male / Rats / Neoplasms / Cachexia / Lipid / Cell Proliferation / Biochemistry and cell biology / Animals / Male / Rats / Neoplasms / Cachexia / Lipid / Cell Proliferation / Biochemistry and cell biology

Glutamate NMDA receptor subunit R1 and GAD mRNA expression in human temporal lobe epilepsy

Molecular Mechanics / Hippocampus / Glutamate / Molecular and cellular biology / Humans / Cellular and Molecular Neurobiology / Female / Male / Temporal Lobe Epilepsy / Synaptic Transmission / Neurons / Middle Aged / mRna expression levels / Adult / Isoenzymes / Neurosciences / Glutamate decarboxylase / Gamma-Aminobutyric Acid / Biochemistry and cell biology / Cellular and Molecular Neurobiology / Female / Male / Temporal Lobe Epilepsy / Synaptic Transmission / Neurons / Middle Aged / mRna expression levels / Adult / Isoenzymes / Neurosciences / Glutamate decarboxylase / Gamma-Aminobutyric Acid / Biochemistry and cell biology

Site-specific incorporation of non-natural residues into peptides: Effect of residue structure on suppression and translation efficiencies

Biochemistry / Organic Chemistry / Beta decay / Animals / Context Effect / Protein structure / Tetrahedron / Amino Acid Profile / Acylation / Rabbits / Amino Acid Sequence / Base Sequence / Chemical Synthesis / Site-directed Mutagenesis / Organic Compound / Nucleic Acid Conformation / Protein Biosynthesis / Biochemistry and cell biology / Organic Acid / Nucleic Acid / Protein structure / Tetrahedron / Amino Acid Profile / Acylation / Rabbits / Amino Acid Sequence / Base Sequence / Chemical Synthesis / Site-directed Mutagenesis / Organic Compound / Nucleic Acid Conformation / Protein Biosynthesis / Biochemistry and cell biology / Organic Acid / Nucleic Acid
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