Bioavailability

Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor

Metabolism / Evaluation / Pharmacokinetics / Drug metabolism / Mitochondria / Dogs / Cell line / Transport / Humans / Permeability / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Bioavailability / Clearance / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding / Dogs / Cell line / Transport / Humans / Permeability / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Bioavailability / Clearance / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding

Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M2 muscarinic receptor antagonists via benzamide modification

Organic Chemistry / Pharmacokinetics / In Vitro / Humans / Animals / Drug Design / Acetylcholine / Bioavailability / Microdialysis / In Vivo / Rats / Rat / Cholinergic Receptor / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Chemical Synthesis / Area Under Curve / Benzamides / Drug Design / Acetylcholine / Bioavailability / Microdialysis / In Vivo / Rats / Rat / Cholinergic Receptor / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Chemical Synthesis / Area Under Curve / Benzamides

Exposure efficiency: an idea whose time has come?

Demography / Evaluation / Transportation / Life Cycle Assessment / Coal / Air pollution / Risk assessment / Multidisciplinary / Power Plant / Risk Analysis / Humans / Incineration / United States / PM / Particles / Absorption / Life Cycle / Power Plants / Bioavailability / Exposure / Particle Size / Particulate Matter / Risk Assessment / Life Cycle Analysis / Fine Particles / Environmental Exposure / Air Pollutants / Fine Particulate Matter / Air pollution / Risk assessment / Multidisciplinary / Power Plant / Risk Analysis / Humans / Incineration / United States / PM / Particles / Absorption / Life Cycle / Power Plants / Bioavailability / Exposure / Particle Size / Particulate Matter / Risk Assessment / Life Cycle Analysis / Fine Particles / Environmental Exposure / Air Pollutants / Fine Particulate Matter

BIOEQUIVALENCE AND PHARMACOKINETIC COMPARISON BETWEEN CLONIDINE HYDROCH-LORIDE TABLETS 0.3MG: AN OPEN LABEL, BA-LANCED, RANDOMIZED-SEQUENCE, SINGLE-DOSE, TWO-PERIOD CROSSOVER STUDY IN HEALTHY MALE VOLUNTEERS

Pharmacology / Pharmacy / Bioavailability

CARACTERIZACION DE LA FIBRA DE CACAO Y SU EFECTO SOBRE LA CAPACIDAD ANTIOXIDANTE EN SUERO DE ANIMALES DE EXPERIMENTACION

Polyphenols / Bioavailability

CARACTERIZACION DE LA FIBRA DE CACAO Y SU EFECTO SOBRE LA CAPACIDAD ANTIOXIDANTE EN SUERO DE ANIMALES DE EXPERIMENTACION

Polyphenols / Bioavailability

A semiparametric deconvolution model to establish in vivo-in vitro correlation applied to OROS oxybutynin

Modeling / Prediction / Pharmacokinetics / Pharmaceutical Chemistry / Dosage Form / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer

Actividad antibacteriana in vitro y biodisponibilidad en vacas de varios preparados de benzilpenicilina g, sola o combinada con sulfato de dihidroestreptomicina

Stability / Bioavailability

Actividad antibacteriana in vitro y biodisponibilidad en vacas de varios preparados de benzilpenicilina G, sola o combinada con sulfato de dihidroestreptomicina

Stability / Bioavailability

Actividad antibacteriana in vitro y biodisponibilidad en vacas de varios preparados de benzilpenicilina g, sola o combinada con sulfato de dihidroestreptomicina

Stability / Bioavailability

4-(2-Pyridyl)piperazine-1-benzimidazoles as potent TRPV1 antagonists

Organic Chemistry / Pharmacokinetics / Ion Channels / Embryo / Cell line / In Vitro / Humans / Capsaicin / Bioavailability / In Vivo / Rat / Benzimidazoles / Structure activity Relationship / Hydrogen-Ion Concentration / Chemical Synthesis / Fluorometry / In Vitro / Humans / Capsaicin / Bioavailability / In Vivo / Rat / Benzimidazoles / Structure activity Relationship / Hydrogen-Ion Concentration / Chemical Synthesis / Fluorometry

A semiparametric deconvolution model to establish in vivo-in vitro correlation applied to OROS oxybutynin

Modeling / Prediction / Pharmacokinetics / Pharmaceutical Chemistry / Dosage Form / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer / Statistics as Topic / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer / Statistics as Topic

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