Base Sequence

Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice

Membrane Proteins / Gene expression / Hepatology / Transgenic Mice / Liver / Mice / Cholesterol / Female / Animals / Male / P-glycoprotein / Liver Function / Membrane transport proteins / Lipoprotein(a) / Clinical Sciences / Protein Expression / High Density Lipoprotein / Base Sequence / Bile / Hyperbilirubinemia / Mice / Cholesterol / Female / Animals / Male / P-glycoprotein / Liver Function / Membrane transport proteins / Lipoprotein(a) / Clinical Sciences / Protein Expression / High Density Lipoprotein / Base Sequence / Bile / Hyperbilirubinemia

Structural and functional characterisation of an influenza virus RNA polymerase-genomic RNA complex

Microbiology / Zoology / Immunology / Molecular Biology / Structural Biology / Biomaterials / Tissue Engineering / Medical Microbiology / Virology / Wastewater Treatment / Hydrogels / Transcription Factors / Multidisciplinary / Extracellular Matrix / Animal Production / Molecular Mechanics / Enzyme Kinetics / Immunogenetics / Catalytic Mechanism / Biological Sciences / Protein Structure and Function / Crystal structure / Molecular Immunology / Heparin / Sequence alignment / Basement Membrane / Biological Wastewater Treatment / Mice / Animals / Blood / Polymerase Chain Reaction / Physical sciences / Special functions / Detoxification / Fisheries Sciences / Fibroblast Growth Factor / Glycosaminoglycan / Transcription Factor / Enzyme / Clinical Sciences / Active site / Polyvinyl alcohol / Poly Vinyl Alcohol / Amino Acid Profile / Veterinary Sciences / Biological activity / Amino Acid Sequence / Base Sequence / Materials Testing / Growth Factor / Structure activity Relationship / Protein Binding / D structure / Biocompatible Materials / Cell Surface Markers / Cardiovascular Magnetic Resonance / Site-directed Mutagenesis / Binding Site / Biochemistry and cell biology / Biomechanical Phenomena / Biomaterials / Tissue Engineering / Medical Microbiology / Virology / Wastewater Treatment / Hydrogels / Transcription Factors / Multidisciplinary / Extracellular Matrix / Animal Production / Molecular Mechanics / Enzyme Kinetics / Immunogenetics / Catalytic Mechanism / Biological Sciences / Protein Structure and Function / Crystal structure / Molecular Immunology / Heparin / Sequence alignment / Basement Membrane / Biological Wastewater Treatment / Mice / Animals / Blood / Polymerase Chain Reaction / Physical sciences / Special functions / Detoxification / Fisheries Sciences / Fibroblast Growth Factor / Glycosaminoglycan / Transcription Factor / Enzyme / Clinical Sciences / Active site / Polyvinyl alcohol / Poly Vinyl Alcohol / Amino Acid Profile / Veterinary Sciences / Biological activity / Amino Acid Sequence / Base Sequence / Materials Testing / Growth Factor / Structure activity Relationship / Protein Binding / D structure / Biocompatible Materials / Cell Surface Markers / Cardiovascular Magnetic Resonance / Site-directed Mutagenesis / Binding Site / Biochemistry and cell biology / Biomechanical Phenomena

Comprehensive molecular diagnosis of 179 Leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing

Medical Genetics / Biological Sciences / Humans / Mutation / Retinitis pigmentosa / Female / Pedigree / Genotype / Reproducibility of Results / Amino Acid Sequence / Base Sequence / Sensitivity and Specificity / Exome / Female / Pedigree / Genotype / Reproducibility of Results / Amino Acid Sequence / Base Sequence / Sensitivity and Specificity / Exome

A DNA polymerase V homologue encoded by TOL plasmid pWW0 confers evolutionary fitness on Pseudomonas putida under conditions of environmental stress

Genetics / Bacteriology / DNA damage / Biological Sciences / Sequence alignment / Pseudomonas putida / Plasmids / Biological evolution / Natural Environment / Time Factors / UV irradiation / Environmental Stress / Base Sequence / Population dynamic / DNA Polymerase / Pseudomonas putida / Plasmids / Biological evolution / Natural Environment / Time Factors / UV irradiation / Environmental Stress / Base Sequence / Population dynamic / DNA Polymerase

A DNA Polymerase V Homologue Encoded by TOL Plasmid pWW0 Confers Evolutionary Fitness on Pseudomonas putida under Conditions of Environmental Stress

Genetics / Bacteriology / DNA damage / Biological Sciences / Sequence alignment / Pseudomonas putida / Plasmids / Biological evolution / Natural Environment / Time Factors / UV irradiation / Environmental Stress / Base Sequence / Population dynamic / DNA Polymerase / Pseudomonas putida / Plasmids / Biological evolution / Natural Environment / Time Factors / UV irradiation / Environmental Stress / Base Sequence / Population dynamic / DNA Polymerase

Uncleaved legumin in developing maize endosperm: identification, accumulation and putative subcellular localization

Electron Microscopy / Plant Biology / Gene expression / Maize / Plant tissue Culture Techniques / Experimental Botany / Subcellular Localization / Molecular cloning / Zea mays / Seeds / Degeneration / Sweet Corn / Amino Acid Sequence / Base Sequence / PLANT PROTEINS / Full Length Movies / Experimental Botany / Subcellular Localization / Molecular cloning / Zea mays / Seeds / Degeneration / Sweet Corn / Amino Acid Sequence / Base Sequence / PLANT PROTEINS / Full Length Movies

Sequence-specific inhibition of RNA polymerase III-dependent transcription using Zorro locked nucleic acid (LNA)

RNA polymerase / DNA / Humans / Mice / Animals / The / Behavioral Animal Models / Clinical Sciences / Transfection / Base Sequence / Oligonucleotides / The / Behavioral Animal Models / Clinical Sciences / Transfection / Base Sequence / Oligonucleotides

Increased (CTG/CAG)n lengths in myotonic dystrophy type 1 and Machado-Joseph disease genes in idiopathic azoospermia patients

DNA / Humans / Spinocerebellar ataxia / Male / Myotonic Dystrophy / Risk factors / Human reproduction / Adult / Genetic Instability / Androgen Receptor / Risk Factors / Trinucleotide Repeat Disorders / Base Sequence / Case Control Studies / Machado-Joseph Disease / Risk factors / Human reproduction / Adult / Genetic Instability / Androgen Receptor / Risk Factors / Trinucleotide Repeat Disorders / Base Sequence / Case Control Studies / Machado-Joseph Disease

Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase

Kinetics / Biological Chemistry / Gene expression / Multidisciplinary / Biological Sciences / Cell line / Humans / Liver / Escherichia coli / Mice / Animals / Biological / Enzyme / Genes / CHEMICAL SCIENCES / Molecular cloning / Protein Sequence Analysis / Rats / Amino Acid Profile / Transfection / Amino Acid Sequence / Base Sequence / Recombinant Proteins / DNA probes / Cell line / Humans / Liver / Escherichia coli / Mice / Animals / Biological / Enzyme / Genes / CHEMICAL SCIENCES / Molecular cloning / Protein Sequence Analysis / Rats / Amino Acid Profile / Transfection / Amino Acid Sequence / Base Sequence / Recombinant Proteins / DNA probes

RNA recognition by designed peptide fusion creates \"artificial\" tRNA synthetase

RNA / Kinetics / Multidisciplinary / Mutation / Escherichia coli / Peptides / Active site / Time Factors / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Protein Binding / aminoacyl-tRNA synthetase / Genetic Code / Nucleic Acid Conformation / Peptides / Active site / Time Factors / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Protein Binding / aminoacyl-tRNA synthetase / Genetic Code / Nucleic Acid Conformation

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Regulation / Nanotechnology / RNA polymerase / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Protein synthesis / Cell Division / Signal Transduction / Transcription / Astronomy / DNA / RNA interference / Mitosis / Cell line / Cell Differentiation / Humans / Mice / Animals / Histone Modification / Cell Signalling / Medical Research / Transcription Factor / ribosomal RNA / Multienzyme complexes / RNA Polymerase I / Cell Proliferation / Base Sequence / Cell Fate / Earth Science / Interphase / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Regulation / Nanotechnology / RNA polymerase / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Protein synthesis / Cell Division / Signal Transduction / Transcription / Astronomy / DNA / RNA interference / Mitosis / Cell line / Cell Differentiation / Humans / Mice / Animals / Histone Modification / Cell Signalling / Medical Research / Transcription Factor / ribosomal RNA / Multienzyme complexes / RNA Polymerase I / Cell Proliferation / Base Sequence / Cell Fate / Earth Science / Interphase

Mutator phenotype of mammalian cells due to deficiency of NEIL1 DNA glycosylase, an oxidized base-specific repair enzyme

DNA replication / DNA damage / DNA repair / Cell line / Humans / Mutation / Animals / Phenotype / Enzyme / Functional integration / Specific Activity / Oxidative Damage / Antisense Oligonucleotide Drugs / Base Sequence / Oxidation-Reduction / Biochemistry and cell biology / Mutation / Animals / Phenotype / Enzyme / Functional integration / Specific Activity / Oxidative Damage / Antisense Oligonucleotide Drugs / Base Sequence / Oxidation-Reduction / Biochemistry and cell biology

Major genomic mitochondrial lineages delineate early human expansions

Genetics / Geography / Population Genetics / East Asia / Population Dynamics / Phylogeny / Mitochondrial DNA / Humans / North Africa / Female / Homo Sapiens / Old World / Human Genome / Base Sequence / Phylogeny / Mitochondrial DNA / Humans / North Africa / Female / Homo Sapiens / Old World / Human Genome / Base Sequence

Genetic characteristics of drug-resistant Vibrio cholerae O1 causing endemic cholera in Dhaka, 2006-2011

Medical Microbiology / Bangladesh / Biological Sciences / Humans / Sequence alignment / Tetracycline / Endemic Diseases / Cholera / Anti-Bacterial Agents / Microbial Sensitivity Tests / Genetic variation / Erythromycin / Ciprofloxacin / Amino Acid Sequence / Base Sequence / Beta Lactamases / Tetracycline / Endemic Diseases / Cholera / Anti-Bacterial Agents / Microbial Sensitivity Tests / Genetic variation / Erythromycin / Ciprofloxacin / Amino Acid Sequence / Base Sequence / Beta Lactamases

Synaptic NMDAR activity suppresses FOXO1 expression via a cis-acting FOXO binding site: FOXO1 is a FOXO target gene

Animals / Channels / Rats / SYNAPSES / Base Sequence / Gene Expression Regulation

Knockdown of Cytosolic Glutaredoxin 1 Leads to Loss of Mitochondrial Membrane Potential: Implication in Neurodegenerative Diseases

Immunohistochemistry / Mitochondria / Multidisciplinary / Neurodegenerative Diseases / Antioxidants / Humans / Reactive Oxygen Species / Polymerase Chain Reaction / Animal Model / PLoS one / Mitochondrial dysfunction / Neurodegenerative Disease / Matrix Metalloproteinases / Mitochondrial Permeability Transition Pore / Base Sequence / Mitochondrial Membrane Potential / Outer Membrane Protein / Nucleotides / Down-Regulation / Humans / Reactive Oxygen Species / Polymerase Chain Reaction / Animal Model / PLoS one / Mitochondrial dysfunction / Neurodegenerative Disease / Matrix Metalloproteinases / Mitochondrial Permeability Transition Pore / Base Sequence / Mitochondrial Membrane Potential / Outer Membrane Protein / Nucleotides / Down-Regulation
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