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Apoptosis
Apoptosis
Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth
Apoptosis / Gene Silencing / Signal Transduction / Dexamethasone / Humans / Child / Mice / Animals / Monoclonal Antibodies / L-asparaginase / Antineoplastic Agents / Molecular Targeted Therapy / Child / Mice / Animals / Monoclonal Antibodies / L-asparaginase / Antineoplastic Agents / Molecular Targeted Therapy
UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells
Leukemia / Apoptosis / Molecular Mechanics / Cell line / Humans / Congestive Heart Failure / Cell Death / Biochemical / BIOCHEMICAL PHARMACOLOGY / Molecular Structure / Congestive Heart Failure / Cell Death / Biochemical / BIOCHEMICAL PHARMACOLOGY / Molecular Structure
Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial KATP channel and potential pERK 1/2 activation
Mitochondria / Apoptosis / Humans / Human right / Cytochrome C / Mitogen Activated Protein Kinase / Caspase / European / Hydrazones / Oxygen / Myocardium / Western blot / Muscle contraction / Potassium Channels / Mechanism of action / Isoproterenol / Mitogen Activated Protein Kinase / Caspase / European / Hydrazones / Oxygen / Myocardium / Western blot / Muscle contraction / Potassium Channels / Mechanism of action / Isoproterenol
HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)
Adolescent / Apoptosis / Nature / Biological Sciences / Humans / Child / Genetic Testing / Mutation / Female / Male / Infant / Proteins / Pedigree / Adult / Autosomal Recessive / Myeloid Cells / Syndrome / Child / Genetic Testing / Mutation / Female / Male / Infant / Proteins / Pedigree / Adult / Autosomal Recessive / Myeloid Cells / Syndrome
Human postnatal dental pulp cells co-differentiate into osteoblasts and endotheliocytes: a pivotal synergy leading to adult bone tissue formation
Immunology / Stem Cells / Cancer / Flow Cytometry / Transmission Electron Microscopy / Stem Cell / Apoptosis / Stem Cell Transplantation / Biological Sciences / Cell Differentiation / Humans / Animals / Cell Death / Cdd / Neurons / Differentiation / Chip / Rats / Adult / Endothelial cell / Time Factors / Adipocytes / Stromal Cells / Three Dimensional / Wistar Rats / Osteogenesis / Angiotensin Converting Enzyme / Osteoblasts / Gene expression profiling / Cell Growth / Stem Cell / Apoptosis / Stem Cell Transplantation / Biological Sciences / Cell Differentiation / Humans / Animals / Cell Death / Cdd / Neurons / Differentiation / Chip / Rats / Adult / Endothelial cell / Time Factors / Adipocytes / Stromal Cells / Three Dimensional / Wistar Rats / Osteogenesis / Angiotensin Converting Enzyme / Osteoblasts / Gene expression profiling / Cell Growth
Cellular prion protein regulates intracellular hydrogen peroxide level and prevents copper-induced apoptosis
Flow Cytometry / Apoptosis / Cerebellum / Copper / Mice / Animals / Cell Death / Neurons / Hydrogen Peroxide / Cell nucleus / Prions / Time Factors / Protein Binding / Cell Survival / Biochemistry and cell biology / Prion Protein / Animals / Cell Death / Neurons / Hydrogen Peroxide / Cell nucleus / Prions / Time Factors / Protein Binding / Cell Survival / Biochemistry and cell biology / Prion Protein
All-trans retinoic acid loaded block copolymer nanoparticles efficiently induce cellular differentiation in HL-60 cells
Nanoparticles / Apoptosis / Block Copolymer / Cell Differentiation / Humans / Reactive Oxygen Species / Cellular differentiation / European / Tretinoin / Physico chemical Properties / Drug Carriers / Drug Release / Lactones / Acute Promyelocytic Leukemia / Polyethylene Glycols / Respiratory Burst / Reactive Oxygen Species / Cellular differentiation / European / Tretinoin / Physico chemical Properties / Drug Carriers / Drug Release / Lactones / Acute Promyelocytic Leukemia / Polyethylene Glycols / Respiratory Burst
All-trans retinoic acid loaded block copolymer nanoparticles efficiently induce cellular differentiation in HL-60 cells
Nanoparticles / Apoptosis / Block Copolymer / Cell Differentiation / Humans / Reactive Oxygen Species / Cellular differentiation / European / Tretinoin / Physico chemical Properties / Drug Carriers / Drug Release / Lactones / Acute Promyelocytic Leukemia / Polyethylene Glycols / Respiratory Burst / Reactive Oxygen Species / Cellular differentiation / European / Tretinoin / Physico chemical Properties / Drug Carriers / Drug Release / Lactones / Acute Promyelocytic Leukemia / Polyethylene Glycols / Respiratory Burst
Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L)
Electron Microscopy / Cell Biology / Confocal Microscopy / Apoptosis / Biological Sciences / Caspases / Cell line / Humans / Animals / Cytochrome C / Monoclonal Antibodies / Proteins / Fluorescent Antibody Technique / The cell / Monoclonal Antibody / Cytoplasm / Apoptotic Protease Activating Factor-1 / Caspases / Cell line / Humans / Animals / Cytochrome C / Monoclonal Antibodies / Proteins / Fluorescent Antibody Technique / The cell / Monoclonal Antibody / Cytoplasm / Apoptotic Protease Activating Factor-1
Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn\'s disease and promotes experimental colitis in vivo
Immunology / Apoptosis / Humans / Mice / Chronic Disease / Female / Animals / Male / Colitis / European / T lymphocytes / Middle Aged / Adult / Colon / Crohn Disease / Interleukin / Interferon gamma / Female / Animals / Male / Colitis / European / T lymphocytes / Middle Aged / Adult / Colon / Crohn Disease / Interleukin / Interferon gamma
Cytotoxic immunological synapses
Immunology / Apoptosis / Signal Transduction / Humans / Natural Killer cells / Animals
Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis
Biochemistry / Genetics / Neuroscience / Immunology / Structural Biology / Structure / RNA / Plant Biology / Cell Cycle / Cell Biology / Apoptosis / Signal Transduction / Biological Sciences / Longevity / Mice / Animals / Cell Signalling / Proteins / Diffuse Large B-Cell Lymphoma / B Lymphocytes / Cell Survival / Structure / RNA / Plant Biology / Cell Cycle / Cell Biology / Apoptosis / Signal Transduction / Biological Sciences / Longevity / Mice / Animals / Cell Signalling / Proteins / Diffuse Large B-Cell Lymphoma / B Lymphocytes / Cell Survival
ER-β expression in large bowel adenomas: Implications in colon carcinogenesis
Immunohistochemistry / Apoptosis / Colorectal cancer / Humans / Intestinal Mucosa / Digestive and Liver Diseases / Female / Male / Clinical Sciences / Aged / Middle Aged / Adenoma / Estrogen receptor-beta / Digestive and Liver Diseases / Female / Male / Clinical Sciences / Aged / Middle Aged / Adenoma / Estrogen receptor-beta
Biophysical characterization of a recombinant leucyl aminopeptidase from Bacillus kaustophilus
Biochemistry / Thermodynamics / Dentistry / Structural Biology / Molecular Dynamics Simulation / Genomics / Protein Folding / Proteomics / Biological Physics / Fluorescent Dyes and Reagents / Apoptosis / Structural Genomics / Ion Channels / Macromolecular X-Ray Crystallography / Protein Stability / HIV / Neurospora crassa / Cell line / Humans / Sequence alignment / Computer Simulation / Circular Dichroism / Mice / Animals / Bacillus / Ligand Binding / Temperature / Urea / Enzyme / Molecular cloning / Amino Acids / Protein Sequence Analysis / Cell nucleus / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Success Rate / Spectrum analysis / Trifluoroethanol / Transfection / Protein Conformation / Molecular weight / Large Scale / Amino Acid Sequence / Calcium Chloride / Protein Quaternary Structure / Recombinant Protein / Structure activity Relationship / Recombinant Proteins / Protein Binding / Hydrogen-Ion Concentration / X Ray Crystallography / Structure Determination / Protein Denaturation / Ligands / Sodium Chloride / Biochemistry and cell biology / Solvents / Genomics / Protein Folding / Proteomics / Biological Physics / Fluorescent Dyes and Reagents / Apoptosis / Structural Genomics / Ion Channels / Macromolecular X-Ray Crystallography / Protein Stability / HIV / Neurospora crassa / Cell line / Humans / Sequence alignment / Computer Simulation / Circular Dichroism / Mice / Animals / Bacillus / Ligand Binding / Temperature / Urea / Enzyme / Molecular cloning / Amino Acids / Protein Sequence Analysis / Cell nucleus / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Success Rate / Spectrum analysis / Trifluoroethanol / Transfection / Protein Conformation / Molecular weight / Large Scale / Amino Acid Sequence / Calcium Chloride / Protein Quaternary Structure / Recombinant Protein / Structure activity Relationship / Recombinant Proteins / Protein Binding / Hydrogen-Ion Concentration / X Ray Crystallography / Structure Determination / Protein Denaturation / Ligands / Sodium Chloride / Biochemistry and cell biology / Solvents
Extended sequence preferences for oligodeoxyribonucleotide activity
Immunology / Apoptosis / Toll like receptor signaling / Mice / Female / Animals / CpG islands / NF-kappa B / B Lymphocytes / Base Sequence / Structure activity Relationship / DNA binding proteins / Interleukin / Animals / CpG islands / NF-kappa B / B Lymphocytes / Base Sequence / Structure activity Relationship / DNA binding proteins / Interleukin
GPC3 reduces cell proliferation in renal carcinoma cell lines
Cell Cycle / Apoptosis / Cancer Genetics / Humans / Female / Renal cell Carcinoma / Male / Glypicans / Middle Aged / Cell Proliferation / Renal cell Carcinoma / Male / Glypicans / Middle Aged / Cell Proliferation
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